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CAZyme Information: MGYG000002372_00999

You are here: Home > Sequence: MGYG000002372_00999

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Clostridium_P perfringens
Lineage Bacteria; Firmicutes_A; Clostridia; Clostridiales; Clostridiaceae; Clostridium_P; Clostridium_P perfringens
CAZyme ID MGYG000002372_00999
CAZy Family GH33
CAZyme Description Sialidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
382 42728.69 5.2259
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002372 3343822 Isolate South Korea Asia
Gene Location Start: 1135491;  End: 1136639  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.18

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH33 22 370 4.3e-75 0.956140350877193

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd15482 Sialidase_non-viral 1.44e-67 23 373 3 334
Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases.
pfam13859 BNR_3 7.17e-34 43 308 4 253
BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases.
COG4409 NanH 2.42e-21 7 382 246 663
Neuraminidase (sialidase) [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis].
COG4409 NanH 7.07e-10 115 268 162 324
Neuraminidase (sialidase) [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis].
pfam13088 BNR_2 2.47e-08 108 271 61 205
BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AQW23307.1 4.73e-288 1 382 1 382
AOY53385.1 4.73e-288 1 382 1 382
ATD49144.1 4.73e-288 1 382 1 382
ABG84018.1 6.44e-286 1 382 1 382
QUD74009.1 6.44e-286 1 382 1 382

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3SIL_A 1.24e-59 33 379 30 375
ChainA, SIALIDASE [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],7AEY_AAA Chain AAA, Sialidase [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
1DIL_A 1.31e-59 33 379 32 377
SialidaseFrom Salmonella Typhimurium Complexed With Apana And Epana Inhibitors [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],1DIM_A Sialidase From Salmonella Typhimurium Complexed With Epana Inhibitor [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],2SIL_A Chain A, SIALIDASE [Salmonella enterica subsp. enterica serovar Typhimurium],2SIM_A Chain A, Sialidase [Salmonella enterica subsp. enterica serovar Typhimurium]
6TRG_XXX 9.59e-59 33 379 30 375
ChainXXX, Sialidase [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],6TVI_AAA Chain AAA, Sialidase [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
7AF2_AAA 1.35e-58 33 379 30 375
ChainAAA, Sialidase [Salmonella enterica subsp. enterica serovar Typhimurium]
1WCS_A 4.96e-34 36 369 38 368
Amutant of Trypanosoma rangeli sialidase displaying trans-sialidase activity [Trypanosoma rangeli]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P10481 1.83e-286 1 382 1 382
Sialidase OS=Clostridium perfringens OX=1502 GN=nanH PE=1 SV=1
P15698 7.09e-209 2 376 20 394
Sialidase OS=Paeniclostridium sordellii OX=1505 PE=1 SV=1
P29768 7.36e-59 33 379 33 378
Sialidase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=nanH PE=1 SV=4
P31206 7.85e-27 32 364 199 528
Sialidase OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=nanH PE=3 SV=2
P23253 1.23e-26 49 364 1 314
Sialidase OS=Trypanosoma cruzi OX=5693 GN=TCNA PE=2 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.999957 0.000085 0.000002 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002372_00999.