CAZyme Information: MGYG000002379_00166

Basic Information

• Species: Lactobacillus acidophilus
• Lineage: Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae; Lactobacillus; Lactobacillus acidophilus
• CAZyme ID: MGYG000002379_00166
• CAZy Family: GH25
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
234	MGYG000002379_1|CGC3	26969.91	10.1891

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002379	2009479	Isolate	not provided	not provided

• Gene Location: Start: 162732; End: 163436 Strand: +

Full Sequence      

MKRYHHKYTLPAILTLLILAIAFLLIGFFNLKKQTTLPPSSNSSAIGIQLNQDVDYVDLH
KLQSNGISFVYLKATQGRSYFDENYLSYRDQILGTKLAFGSMITYSNESTPLQHYRYFFS
QVGNNTGSLPILIEPINSRSKKYLRSMGQFTRMLEKHGKSVIINIDYKYHNYFDAQTKFM
SSDAKSPNKLKYSFWRYTTNGRVKNLAGLEKGVTMYSYNGTVGQYKQKYGQLTQ

Enzyme Prediction     

No EC number prediction in MGYG000002379_00166.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH25	55	204	2.8e-23	0.943502824858757

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd06419	GH25_muramidase_2	6.86e-71	38	214	1	190	Uncharacterized bacterial muramidase containing a glycosyl hydrolase family 25 (GH25) catalytic domain. Endo-N-acetylmuramidases are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues.
cd00599	GH25_muramidase	4.00e-16	47	221	2	171	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. This family of muramidases contains a glycosyl hydrolase family 25 (GH25) catalytic domain and is found in bacteria, fungi, slime molds, round worms, protozoans and bacteriophages. The bacteriophage members are referred to as endolysins which are involved in lysing the host cell at the end of the replication cycle to allow release of mature phage particles. Endolysins are typically modular enzymes consisting of a catalytically active domain that hydrolyzes the peptidoglycan cell wall and a cell wall-binding domain that anchors the protein to the cell wall. Endolysins generally have narrow substrate specificities with either intra-species or intra-genus bacteriolytic activity.
cd06413	GH25_muramidase_1	2.50e-15	57	220	15	191	Uncharacterized bacterial muramidase containing a glycosyl hydrolase family 25 (GH25) catalytic domain. Endo-N-acetylmuramidases are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues.
pfam01183	Glyco_hydro_25	2.04e-09	51	203	7	177	Glycosyl hydrolases family 25.
cd06524	GH25_YegX-like	1.36e-07	61	220	20	194	YegX is an uncharacterized bacterial protein with a glycosyl hydrolase family 25 (GH25) catalytic domain that is similar in sequence to the CH-type (Chalaropsis-type) lysozymes of the GH25 family of endolysins.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AAV42495.1	1.19e-168	1	234	1	234
AVW86443.1	1.19e-168	1	234	1	234
QKQ20429.1	1.19e-168	1	234	1	234
AGK93819.1	1.19e-168	1	234	1	234
ASX14592.1	1.19e-168	1	234	1	234

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.999997	0.000032	0.000001	0.000000	0.000000	0.000003

TMHMM  Annotations     

start	end
7	29