CAZyme Information: MGYG000002394_00951

Basic Information

• Species: Prevotella rara
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotella; Prevotella rara
• CAZyme ID: MGYG000002394_00951
• CAZy Family: GH115
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
837	MGYG000002394_5|CGC1	96151.17	6.3265

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002394	3788330	Isolate	Russia	Europe

• Gene Location: Start: 124758; End: 127271 Strand: +

Full Sequence      

MKNKVVTAFVFFIFFASLKAFSANSFISFSAGDMLLNQNNEVTIFVDQNDCKGVMTAVRN
MSTDINKVCGADVKISTSSNNAKIIVGTIGHSAAIDKIMKQRKNDMKQLKGKREMYVITI
DNGQLVIAGSDRRGTIYGIYELSKQIGVSPWYYWADTPIEQHKHIYIKKGVYTDGEPAVR
YRGIFLNDEAPCLTTWVKNTFGTEYGNHEFYAKVFELILRLKGNLLWPAMWGWAFYADDE
LNSKTADEMGVIIGTSHHEPMARNHQEWARNRDKYGKWNYNTNQEVLDKFFKEGIERRQG
TEDIVTIGMRGDGDEAMSEESDVALLEKIIRNQRQIISDVTKQRADKTPQMWALYKEVMD
YYDKGMKVPDDVTILLCDDNWGNVRRVPNAKEAKRAGGWGLYYHVDYVGAPRNSKWINVT
PTQNMWEQLSLASEYGIDRIWILNVGDLKPMEYPISLFLDMAWNPKRYNETNITDHTLDF
CKQQFGDEQAEEAARLLNLCCKYNGRITAEMLDRNTYNLETGEWEKVVNDYMKLEAEALR
QFITLKDEYKDTYREIILFPIQAMGNLYQMYFAQAMNHKLYKNNDPDANKWADKVEEAFR
RDSVLCAQYNHEIAGGKWNGMMIQKHIGYTSWNDDFEKDILPEVFRIAENDAEGGFIHKA
SNGYAAIEAEHFYSKTDAKDAKWTVIPFMGRTLSGISLRPYNKEVEGAGLTYRFVTDGKY
TGDVKVYVVVKSTLDFLNKGGVTYNISIDGSKAKTINFNKDLNESPENIYTVYYPTVARR
VVESVITLPLGKTSDNMHEIKITPNDPGIVFEKIVIDMGGYKNSYLHMKESEKFRTM

Enzyme Prediction     

EC	3.2.1.131

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH115	35	814	1.2e-274	0.9913916786226685

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam15979	Glyco_hydro_115	0.0	175	511	1	334	Glycosyl hydrolase family 115. Glyco_hydro_115 is a family of glycoside hydrolases likely to have the activity of xylan a-1,2-glucuronidase, EC:3.2.1.131, or a-(4-O-methyl)-glucuronidase EC:3.2.1.-.
pfam17829	GH115_C	3.53e-41	655	830	1	172	Gylcosyl hydrolase family 115 C-terminal domain. This domain is found at the C-terminus of glycosyl hydrolase family 115 proteins. This domain has a beta-sandwich fold.
pfam03648	Glyco_hydro_67N	0.004	76	142	56	120	Glycosyl hydrolase family 67 N-terminus. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the N-terminal region of alpha-glucuronidase. The N-terminal domain forms a two-layer sandwich, each layer being formed by a beta sheet of five strands. A further two helices form part of the interface with the central, catalytic, module (pfam07488).

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CCG34758.1	0.0	34	837	1	804
CCG34736.1	0.0	34	622	1	589
BCS85271.1	0.0	12	831	11	828
QNT66545.1	0.0	22	822	24	846
QUT26893.1	0.0	11	835	8	842

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4C90_A	0.0	11	835	19	853	Evidencethat GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C90_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_A Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus]
7PUG_A	0.0	35	835	19	838	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
7PXQ_A	0.0	35	835	18	837	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
4ZMH_A	1.86e-177	26	655	5	643	Crystalstructure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40],4ZMH_B Crystal structure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40]
6NPS_A	4.67e-111	33	639	10	652	Crystalstructure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112],6NPS_B Crystal structure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000252	0.999089	0.000147	0.000177	0.000156	0.000149

TMHMM  Annotations     

start	end
5	27