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CAZyme Information: MGYG000002401_01648
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Propionibacterium freudenreichii | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Actinobacteriota; Actinomycetia; Propionibacteriales; Propionibacteriaceae; Propionibacterium; Propionibacterium freudenreichii | |||||||||||
| CAZyme ID | MGYG000002401_01648 | |||||||||||
| CAZy Family | GT39 | |||||||||||
| CAZyme Description | putative dolichyl-phosphate-mannose--protein mannosyltransferase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 1803178; End: 1804737 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT39 | 27 | 293 | 5.2e-73 | 0.9865470852017937 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG1928 | PMT1 | 2.92e-25 | 22 | 248 | 25 | 225 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
| pfam02366 | PMT | 5.92e-14 | 29 | 248 | 5 | 198 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
| COG4346 | COG4346 | 1.28e-11 | 93 | 260 | 136 | 271 | Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase [Posttranslational modification, protein turnover, chaperones]. |
| COG1807 | ArnT | 3.09e-07 | 93 | 255 | 64 | 201 | 4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis]. |
| pfam13231 | PMT_2 | 7.72e-06 | 92 | 254 | 1 | 137 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| CEP27207.1 | 0.0 | 1 | 519 | 26 | 544 |
| ARO12442.1 | 0.0 | 1 | 519 | 1 | 519 |
| AJQ91374.1 | 0.0 | 1 | 519 | 1 | 519 |
| AWY95252.1 | 0.0 | 1 | 519 | 1 | 519 |
| CUW18330.1 | 0.0 | 1 | 519 | 1 | 519 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| L8F4Z2 | 7.42e-87 | 16 | 518 | 33 | 515 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1 |
| P9WN04 | 2.85e-84 | 16 | 518 | 39 | 521 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2 |
| P9WN05 | 2.85e-84 | 16 | 518 | 39 | 521 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2 |
| Q8NRZ6 | 5.48e-68 | 20 | 518 | 37 | 519 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000032 | 0.000002 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 20 | 39 |
| 112 | 134 |
| 141 | 160 |
| 164 | 183 |
| 196 | 218 |
| 233 | 250 |
| 271 | 293 |
| 394 | 411 |
| 416 | 433 |
| 443 | 465 |
| 478 | 500 |