Species | Clostridium_H massiliodielmoense | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Lineage | Bacteria; Firmicutes_A; Clostridia; Clostridiales; Clostridiaceae; Clostridium_H; Clostridium_H massiliodielmoense | |||||||||||
CAZyme ID | MGYG000002402_01108 | |||||||||||
CAZy Family | GH23 | |||||||||||
CAZyme Description | Membrane-bound lytic murein transglycosylase F | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location | Start: 431297; End: 431953 Strand: - |
Family | Start | End | Evalue | family coverage |
---|---|---|---|---|
GH23 | 106 | 217 | 5.2e-29 | 0.7851851851851852 |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
cd00254 | LT-like | 2.03e-45 | 107 | 217 | 2 | 111 | lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
cd16896 | LT_Slt70-like | 5.48e-41 | 95 | 218 | 8 | 146 | uncharacterized lytic transglycosylase subfamily with similarity to Slt70. Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
cd13401 | Slt70-like | 6.09e-41 | 93 | 216 | 8 | 146 | 70kDa soluble lytic transglycosylase (Slt70) and similar proteins. Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda. |
COG0741 | MltE | 1.89e-30 | 20 | 216 | 63 | 280 | Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell wall/membrane/envelope biogenesis]. |
cd13403 | MLTF-like | 1.24e-29 | 98 | 216 | 4 | 156 | membrane-bound lytic murein transglycosylase F (MLTF) and similar proteins. This subfamily includes membrane-bound lytic murein transglycosylase F (MltF, murein lyase F) that degrades murein glycan strands. It is responsible for catalyzing the release of 1,6-anhydromuropeptides from peptidoglycan. Lytic transglycosylase catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc) as do goose-type lysozymes. However, in addition, it also makes a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
ABK62407.1 | 2.99e-138 | 1 | 218 | 1 | 217 |
AEB76776.1 | 3.01e-127 | 1 | 218 | 1 | 219 |
QPW61066.1 | 7.07e-126 | 1 | 218 | 1 | 219 |
QPW58196.1 | 7.07e-126 | 1 | 218 | 1 | 219 |
QPW55125.1 | 6.17e-120 | 1 | 218 | 1 | 219 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
1SLY_A | 4.86e-11 | 104 | 215 | 466 | 594 | ComplexOf The 70-Kda Soluble Lytic Transglycosylase With Bulgecin A [Escherichia coli] |
5MPQ_A | 6.44e-11 | 99 | 213 | 424 | 549 | BulgecinA: The key to a broad-spectrum inhibitor that targets lytic transglycosylases [Neisseria meningitidis] |
5O1J_A | 6.45e-11 | 99 | 213 | 428 | 553 | Lytictransglycosylase in action [Neisseria meningitidis MC58] |
6FPN_B | 6.47e-11 | 99 | 213 | 434 | 559 | Lytictransglycosylase in action [Neisseria meningitidis MC58] |
5O24_A | 6.48e-11 | 99 | 213 | 438 | 563 | Lytictransglycosylase in action [Neisseria meningitidis] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
O31608 | 3.93e-37 | 82 | 216 | 51 | 179 | Putative murein lytic transglycosylase YjbJ OS=Bacillus subtilis (strain 168) OX=224308 GN=yjbJ PE=3 SV=1 |
O31976 | 5.69e-26 | 95 | 218 | 1426 | 1543 | SPbeta prophage-derived uncharacterized transglycosylase YomI OS=Bacillus subtilis (strain 168) OX=224308 GN=yomI PE=3 SV=2 |
O64046 | 5.69e-26 | 95 | 218 | 1426 | 1543 | Probable tape measure protein OS=Bacillus phage SPbeta OX=66797 GN=yomI PE=3 SV=1 |
P27380 | 4.77e-16 | 86 | 183 | 2 | 98 | Transglycosylase OS=Enterobacteria phage PRD1 OX=10658 GN=VII PE=1 SV=3 |
A8ZWR8 | 1.88e-12 | 95 | 188 | 290 | 389 | Membrane-bound lytic murein transglycosylase F OS=Desulfococcus oleovorans (strain DSM 6200 / JCM 39069 / Hxd3) OX=96561 GN=mltF PE=3 SV=2 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
---|---|---|---|---|---|
1.000056 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |
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