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CAZyme Information: MGYG000002406_00546

You are here: Home > Sequence: MGYG000002406_00546

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Corynebacterium pacaense
Lineage Bacteria; Actinobacteriota; Actinomycetia; Mycobacteriales; Mycobacteriaceae; Corynebacterium; Corynebacterium pacaense
CAZyme ID MGYG000002406_00546
CAZy Family GT53
CAZyme Description putative arabinosyltransferase C
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1134 121814.79 4.7005
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002406 3028764 Isolate not provided not provided
Gene Location Start: 575876;  End: 579280  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.2.-

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT53 28 1132 0 0.9971401334604385

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam04602 Arabinose_trans 0.0 218 689 1 458
Mycobacterial cell wall arabinan synthesis protein. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol.
pfam14896 Arabino_trans_C 0.0 742 1132 1 384
EmbC C-terminal domain. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol. This domain represents the C-terminal extracellular domain that is likely to bind to carbohydrate.
pfam17689 Arabino_trans_N 9.37e-56 54 214 1 155
Arabinosyltransferase concanavalin like domain. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ALC04696.1 0.0 1 1134 28 1156
BAU94565.1 0.0 1 1134 28 1156
BAF53230.1 0.0 1 1134 28 1156
AGN17846.1 0.0 1 1134 17 1145
AGN20869.1 0.0 1 1134 17 1145

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
7BVE_A 5.72e-293 28 1133 13 1073
Cryo-EMstructure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155],7BVE_B Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155]
7BVH_A 1.03e-292 1 1133 1 1086
Crystalstructure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose [Mycolicibacterium smegmatis MC2 155],7BVH_B Crystal structure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose [Mycolicibacterium smegmatis MC2 155]
7BWR_A 4.26e-256 28 1133 27 1080
Mycobacteriumsmegmatis arabinosyltransferase complex EmbB2-AcpM2 in substrate DPA bound asymmetric 'active state' [Mycolicibacterium smegmatis MC2 155],7BWR_B Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in substrate DPA bound asymmetric 'active state' [Mycolicibacterium smegmatis MC2 155],7BX8_A Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in symmetric 'resting state' [Mycolicibacterium smegmatis MC2 155],7BX8_B Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in symmetric 'resting state' [Mycolicibacterium smegmatis MC2 155]
6X0O_A 6.99e-256 28 1133 27 1080
Single-ParticleCryo-EM Structure of Arabinosyltransferase EmbB from Mycobacterium smegmatis [Mycolicibacterium smegmatis MC2 155]
7BVC_B 7.43e-256 28 1133 27 1080
Cryo-EMstructure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155],7BVG_B Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with di-arabinose. [Mycolicibacterium smegmatis MC2 155]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q50393 4.07e-290 28 1133 13 1073
Probable arabinosyltransferase C OS=Mycolicibacterium smegmatis OX=1772 GN=embC PE=3 SV=2
Q7TVN4 7.99e-272 24 1132 23 1092
Probable arabinosyltransferase C OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) OX=233413 GN=embC PE=3 SV=1
P9WNL5 2.25e-271 24 1132 23 1092
Probable arabinosyltransferase C OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=embC PE=1 SV=1
P9WNL4 3.18e-271 24 1132 23 1092
Probable arabinosyltransferase C OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=embC PE=3 SV=1
Q9CDA7 2.64e-269 29 1132 9 1069
Probable arabinosyltransferase C OS=Mycobacterium leprae (strain TN) OX=272631 GN=embC PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.999981 0.000032 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      download full data without filtering help

start end
224 241
336 353
373 390
411 433
437 454
474 496
542 564
571 588
598 620
627 649
664 686
723 745