CAZyme Information: MGYG000002414_00483

Basic Information

• Species: Paenibacillus odorifer
• Lineage: Bacteria; Firmicutes; Bacilli; Paenibacillales; Paenibacillaceae; Paenibacillus; Paenibacillus odorifer
• CAZyme ID: MGYG000002414_00483
• CAZy Family: SLH
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
2100		221422.87	4.5013

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002414	6802552	Isolate	South Korea	Asia

• Gene Location: Start: 536618; End: 542920 Strand: -

Full Sequence      

MIISSRVRKWFATGLAMLMIAGSVLPAVQTAEAAPDNSNIVISQVYGGGGNGGAEFKSDF
IELYNPTNHPVDLTGWKVRYTSAAGTFSSGTDLNGTIPANGYFLIEEAAGSGGTTDLPTP
DVSKGILAMSGTNGKVDLVDKSGTTVDLVGYGTATNVEGNATAALSNTTAAIRKAAAGAP
ADSRGLDTDNNSKDFVVQAPSPRNSAYGTLPELPETASSAVALPAPNAWPAGTEISLNSP
TVGASVYAAVYGSGGSTNFQPYTGPITLTEDTTIKAYASEPNMPDSPVSTFDYTILAKTD
VATARLASKGQNILTEGIVTHINAAKMYIQDESGGIVLYGFPEFANVGDRVEVSGTMDIY
SNLQEIKFQSGLQYNVAAQNVGVPAPKLITATDLSAANGESHEAQLVTMNNVTIDNVNGS
TVTASQGGQPFTIFSTLPKLVKGKTFDNITGVIEQYSTTYQFIPLNENALVEETFSVMAS
PGAGRIIKGSSVTLSSPTLGAQIYYTTNGTEPTTASKLYSDPITVNQDLTIYAIVVADGK
TSKVYTFAYKASELPRIHDIQGESHTSEYAGQNVSDVEGIVTQYGYTFATGAYRGFFMQD
PQPDDNVNTSEGIFVYSTNSSLKPQIGDLVQVSGAVSEYNEGNASNLTSTQITMTSIKAD
SSSSYTVPEPVVLGKGGRAIPSSIIDNDGMADFEPNEDAIDFYESLEGMLVKLPTPTIIS
PYWTSGSGNSMLYNIPTRVENDTPDVITPAGGLVLKEYNQYNPQRLIIAYGNPGQEVITG
DKFAGDVTGVIGYNNGNFKVIPENGKLPAITPSTFKQETTTLEVNDSKLLIASYNIENFY
PGVGATKIQKLADSITNNMKKPDIIGVVEMQDSNGETNNGITEASAAELIKAIETAGGPV
YKYTDIAPENNMDGGAPGGNIRVGFLYNPARVQLADSVSGQKGTATQSVGYNAAADQLTY
NPGRIDPTNSAFTSSRKPLAAQFVFGGETVIVIANHFNSKGGDTAPFGNVQPPVLSSETQ
RHKIAAVVNGFVKEVLTANPKANIVALGDLNDFQFTKTATLLKGTELDNLIDTLPLNEQY
TYTYDGNSQVLDHILVSKNLTASSKVDVVHLNADFSPSNGRVSDHDAVLAQIDFNTAEDF
PLTILHTNDTHAGLDTVSSPNNILRRVTAIKEAKATTENPILVDAGDVFSGTLYFNKYLG
QADLAFMNLVKYDAMTFGNHEFDKDSDILSKFIGNAKFPFVSSNVNFSADDILSKMFANE
IGRSGNAGTIYPALIKEVDGQQVGIMGLTTEDTANIASPGKVTFENAFAKAEATVAMLEK
EKVNKIIVLSHLGYEEDLKLAKAVNGIDIIVGGHSHTQLNQAVVDNTDPNAPKLIVQTGE
KGLFLGQLEVKFNQDGVLTDWKDQLISIDAKNGTNYVIAEDPEAKQILDTEYKPGIQELT
NEVVGNSEVVLNGVRDNVRTKETNLGNLIADGMLYAAQKAGTNAVIALQNGGGIRESINE
GPITQGEVLGVLPFNNDLVTITLTGQEIKDAMENGVSKTPAADGRFPHVAGLKFYYDSTK
PVNERVLRIEVKNGDKYVPLDLNASYEVATNAFTAKGGDFYTSLEKAYKEGRVNLLYLPD
FDVFTKYLQKVGTVTANTSAVEGRIVDLKGAPLPETNPTPTPDPTPVPTPDPTSVPTSVP
TSVPTSAPTVPTATATPSPTVAPTAAPIASAQVTTINAADLTKLLAELPAGSQELVIPVK
ATTGGAQVVLPGSVLVKQAAAQPNTVLTFTTDGASYSLPLRVVNSAALAAQLGISDFTIT
VSILVANSGTLSSTNQAITSQLGNATLAAPVIEFSVSAQAGTKSVPLNNFGSTYVKRTIN
VPAVLNSNNATAVVFDPASGKISFVPAIFVPKADGTTDVTIKRNSNSYYTVVKSSKTFAD
TNGHWAKSSIDLLATKLIVSGTSNDTFSPSQSITRAEFAALITRSLGLATGNGETTFKDV
NSSAWYADAIRTAAEAGLISGYTDGSFKPGSPITRQEMASVLAKAIKYTGKTLNADPAAL
AKFSDAASIPAWSQAAVAEIAAEGIIQGATDGSFAPQKLATRAEAVTMLEKTLKSLQFIN

Enzyme Prediction     

No EC number prediction in MGYG000002414_00483.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
SLH	1977	2017	7e-17	0.9523809523809523

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
PRK09419	PRK09419	1.35e-120	1142	1645	661	1143	multifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase/5'-nucleotidase.
COG0737	UshA	3.74e-97	1136	1646	21	513	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family [Nucleotide transport and metabolism, Defense mechanisms].
PRK09558	ushA	5.36e-92	1142	1646	35	549	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed
cd07409	MPP_CD73_N	3.19e-86	1142	1402	1	273	CD73 ecto-5'-nucleotidase and related proteins, N-terminal metallophosphatase domain. CD73 is a mammalian ecto-5'-nucleotidase expressed in endothelial cells and lymphocytes that catalyzes the conversion of 5'-AMP to adenosine in the final step of a pathway that generates adenosine from ATP. This pathway also includes a CD39 nucleoside triphosphate dephosphorylase that mediates the dephosphorylation of ATP to ADP and then to 5'-AMP. These enzymes all have an N-terminal metallophosphatase domain and a C-terminal 5'nucleotidase domain. The N-terminal metallophosphatase domain belongs to a large superfamily of distantly related metallophosphatases (MPPs) that includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.
COG2374	COG2374	5.27e-76	410	1133	37	787	Predicted extracellular nuclease [General function prediction only].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CCH00931.1	3.44e-119	556	1134	338	926
API54465.1	6.56e-97	1139	1660	25	546
QSW23924.1	3.35e-95	1139	1651	25	536
QSZ00291.1	3.49e-95	1139	1657	25	543
QIJ42120.1	3.49e-95	1139	1657	25	543

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2Z1A_A	7.15e-107	1140	1645	28	528	Crystalstructure of 5'-nucleotidase precursor from Thermus thermophilus HB8 [Thermus thermophilus HB8]
5H7W_A	4.44e-69	1140	1651	3	528	Crystalstructure of 5'-nucleotidase from venom of Naja atra [Naja atra],5H7W_B Crystal structure of 5'-nucleotidase from venom of Naja atra [Naja atra]
7D0V_A	6.16e-69	1140	1646	3	523	ChainA, Snake venom 5'-nucleotidase [Naja atra],7D0V_B Chain B, Snake venom 5'-nucleotidase [Naja atra]
4H1Y_P	1.66e-63	1142	1645	26	543	Humanecto-5'-nucleotidase (CD73): crystal form II (open) in complex with PSB11552 [Homo sapiens],6TVE_P Unliganded human CD73 (5'-nucleotidase) in the open state [Homo sapiens],6TVG_A Human CD73 (ecto 5'-nucleotidase) in complex with AMPCP in the open state [Homo sapiens],7BBJ_A Chain A, 5'-nucleotidase [Homo sapiens],7BBJ_B Chain B, 5'-nucleotidase [Homo sapiens],7P9N_A Chain A, 5'-nucleotidase [Homo sapiens],7P9R_A Chain A, 5'-nucleotidase [Homo sapiens],7P9T_A Chain A, 5'-nucleotidase [Homo sapiens],7PA4_A Chain A, 5'-nucleotidase [Homo sapiens],7PB5_A Chain A, 5'-nucleotidase [Homo sapiens],7PBA_A Chain A, 5'-nucleotidase [Homo sapiens],7PBB_A Chain A, 5'-nucleotidase [Homo sapiens],7PBY_A Chain A, 5'-nucleotidase [Homo sapiens],7PCP_A Chain A, 5'-nucleotidase [Homo sapiens],7PD9_A Chain A, 5'-nucleotidase [Homo sapiens]
4H2B_A	1.70e-63	1142	1645	27	544	Humanecto-5'-nucleotidase (CD73): crystal form II (open) in complex with Baicalin [Homo sapiens]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
O34313	4.20e-111	890	1648	462	1177	Trifunctional nucleotide phosphoesterase protein YfkN OS=Bacillus subtilis (strain 168) OX=224308 GN=yfkN PE=1 SV=1
P29240	1.51e-69	1127	1657	17	559	5'-nucleotidase OS=Diplobatis ommata OX=1870830 PE=2 SV=1
A9BJC1	3.73e-69	1142	1648	24	499	Mannosylglucosyl-3-phosphoglycerate phosphatase OS=Petrotoga mobilis (strain DSM 10674 / SJ95) OX=403833 GN=mggB PE=1 SV=1
A0A2I4HXH5	2.43e-68	1140	1651	3	528	Snake venom 5'-nucleotidase (Fragment) OS=Naja atra OX=8656 PE=1 SV=1
F8S0Z7	4.63e-64	1137	1646	39	562	Snake venom 5'-nucleotidase OS=Crotalus adamanteus OX=8729 PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000377	0.998821	0.000185	0.000234	0.000173	0.000160

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002414_00483.