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CAZyme Information: MGYG000002453_02449
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Akkermansia muciniphila_B | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Verrucomicrobiota; Verrucomicrobiae; Verrucomicrobiales; Akkermansiaceae; Akkermansia; Akkermansia muciniphila_B | |||||||||||
| CAZyme ID | MGYG000002453_02449 | |||||||||||
| CAZy Family | GH18 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 972057; End: 973499 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH18 | 181 | 464 | 2.7e-40 | 0.956081081081081 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam00704 | Glyco_hydro_18 | 8.53e-40 | 181 | 457 | 1 | 307 | Glycosyl hydrolases family 18. |
| cd06548 | GH18_chitinase | 4.15e-36 | 221 | 457 | 61 | 322 | The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an eight-stranded alpha/beta barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel. |
| smart00636 | Glyco_18 | 1.25e-32 | 207 | 457 | 26 | 334 | Glyco_18 domain. |
| cd00598 | GH18_chitinase-like | 2.33e-32 | 182 | 457 | 1 | 210 | The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods. Chitinases have been identified in viruses, bacteria, fungi, protozoan parasites, insects, and plants. The structure of the GH18 domain is an eight-stranded beta/alpha barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel. The GH18 family includes chitotriosidase, chitobiase, hevamine, zymocin-alpha, narbonin, SI-CLP (stabilin-1 interacting chitinase-like protein), IDGF (imaginal disc growth factor), CFLE (cortical fragment-lytic enzyme) spore hydrolase, the type III and type V plant chitinases, the endo-beta-N-acetylglucosaminidases, and the chitolectins. The GH85 (glycosyl hydrolase, family 85) ENGases (endo-beta-N-acetylglucosaminidases) are closely related to the GH18 chitinases and are included in this alignment model. |
| cd06545 | GH18_3CO4_chitinase | 3.35e-27 | 218 | 470 | 34 | 253 | The Bacteroides thetaiotaomicron protein represented by pdb structure 3CO4 is an uncharacterized bacterial member of the family 18 glycosyl hydrolases with homologs found in Flavobacterium, Stigmatella, and Pseudomonas. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QUY60202.1 | 0.0 | 1 | 480 | 1 | 480 |
| QHV63883.1 | 0.0 | 1 | 480 | 1 | 480 |
| QHV76251.1 | 0.0 | 1 | 480 | 1 | 480 |
| QWP48297.1 | 0.0 | 1 | 480 | 1 | 480 |
| QWP72903.1 | 0.0 | 1 | 480 | 1 | 480 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 3CO4_A | 3.28e-17 | 237 | 452 | 53 | 279 | Crystalstructure of a chitinase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],3FND_A Crystal structure of a chitinase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron] |
| 6XYZ_A | 1.83e-15 | 199 | 452 | 31 | 285 | Crystalstructure of the GH18 chitinase ChiB from the chitin utilization locus of Flavobacterium johnsoniae [Flavobacterium johnsoniae UW101] |
| 6IGY_A | 1.98e-15 | 270 | 457 | 125 | 361 | Crystalstructure of Aspergillus niger chitinase B [Aspergillus niger] |
| 6INX_A | 7.19e-15 | 258 | 457 | 75 | 329 | Structuralinsights into a novel glycoside hydrolase family 18 N-acetylglucosaminidase from Paenibacillus barengoltzii [Paenibacillus barengoltzii] |
| 5WUS_A | 1.86e-14 | 248 | 457 | 71 | 342 | Crystalstructure of a insect group III chitinase (CAD2) from Ostrinia furnacalis [Ostrinia furnacalis],5WVH_A Crystal structure of an insect group III chitinase complex with (GlcNAc)6 (CAD2-(GlcNAc)6) from Ostrinia furnacalis [Ostrinia furnacalis] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q9W5U2 | 4.84e-16 | 266 | 457 | 2002 | 2253 | Probable chitinase 10 OS=Drosophila melanogaster OX=7227 GN=Cht10 PE=2 SV=2 |
| P32470 | 4.89e-15 | 262 | 452 | 139 | 378 | Chitinase 1 OS=Aphanocladium album OX=12942 GN=CHI1 PE=1 SV=2 |
| G5EAZ3 | 1.35e-14 | 265 | 457 | 109 | 347 | Endochitinase B OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=chiB PE=1 SV=1 |
| Q92222 | 1.35e-14 | 265 | 457 | 109 | 347 | Endochitinase B OS=Emericella nidulans OX=162425 GN=chiB PE=1 SV=3 |
| O14456 | 8.75e-14 | 262 | 457 | 140 | 383 | Endochitinase 1 OS=Metarhizium anisopliae OX=5530 GN=chit1 PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000270 | 0.999039 | 0.000191 | 0.000174 | 0.000148 | 0.000135 |