CAZyme Information: MGYG000002455_00676

Basic Information

• Species: Bacteroides cellulosilyticus
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides cellulosilyticus
• CAZyme ID: MGYG000002455_00676
• CAZy Family: GH3
• CAZyme Description: Beta-hexosaminidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1046	MGYG000002455_2|CGC7	115973.74	9.4902

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002455	6974062	Isolate	United States	North America

• Gene Location: Start: 385756; End: 388896 Strand: +

Full Sequence      

MKKLFLFLLILFSCCARFDAQTHRLPAPQSTVTPVEPILMRPFTNDARCRQWVDSVLNKM
SLKERIGQLFIYTIAPQQDKANRDLLRKVVDDYKVGGLLFSGGLMENQVALTNEAQKMAD
IPLMITFDGEWGLSMRLRGTPVFPRNMVLGCIQNDSLLYGYGCEMARQCRELGVQVNFAP
VADVNFNPKNPVINTRSFGESPVNVADKVIAYARGLEDGGVLSVSKHFPGHGDTDVDSHH
SLPKLSFSRARLDSVELYPFRKVIQAGLSGMMVGHLEVPVLEPKRGVPSSLSRKVVHDLL
TQEMQFKGLVFTDALAMKGVSANNTSICLQALQAGHDLLLVPRRIKEEVEAILDAVKSGE
LTEAEIETKCRKVLTYKYALGLSKKPFVRLSGLGNRINTAHTRDLIRRLNEEAITVLRNK
NNVLPLDADTREVAVLNVGDAKEVQPFLKELSGYINSAGTKGSPTVFQLKKDLQPAARKL
LRDSLSQYKRILVCVTEHRLAPYQPFFAEFTHDVPAVYLLFIPGKQMLQIRRAVSAADAV
VLAHSSIDDVQCRTAKILYGDATADGRLSASISNLFATGTGQVITPKTPLHFVPDEYGVN
SRLLTRIDEIAKEGIKEGAYPGCQIVILKDGKEMYNKAFGTHTWPSTSANRLSASVTPGA
TLPVSPTDVYDLASLTKTTATLLAVMKLYDKGRLNLTDRVSDYLPWLQDTDKKDITVRQL
LLHESGLPSTLLFYLEAIDKESYEGTLFKAKPDAAHSAQIGVRTWANPKFKFQKGLTSKV
RTAEHTLQVSDSLWLNRSFKEAYRQKIIETPLRDRRYRYSCVGFILLQQLVEARTGMSMD
AFLEQEFYAPMGLKRTGYLPLRGAATAGTAYAGIVSGSHAPLSKAEIIPSSFDPFLRKTV
LQGFVHDESAAFQGGVSGNAGLFSNATEVARIYQMLLNGGELDGKRYLSPETCRVFTTTV
SRISRRGLGFDKPDRQNPAKSPCAAATPSTVYGHTGFTGTCAWVDPTNGLVYVFLCNRIY
PNVWNTKLMKMDIRTRIQEVMYQAVK

Enzyme Prediction     

EC	3.2.1.-

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH3	115	341	1.4e-53	0.9861111111111112

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG1472	BglX	4.69e-77	60	436	1	360	Periplasmic beta-glucosidase and related glycosidases [Carbohydrate transport and metabolism].
pfam00933	Glyco_hydro_3	1.87e-75	61	375	1	315	Glycosyl hydrolase family 3 N terminal domain.
PRK03642	PRK03642	1.44e-52	583	1046	24	432	putative periplasmic esterase; Provisional
pfam00144	Beta-lactamase	8.54e-43	607	1023	1	313	Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.
COG1680	AmpC	1.71e-40	554	1022	1	367	CubicO group peptidase, beta-lactamase class C family [Defense mechanisms].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QUT89658.1	0.0	1	1046	1	1046
ALJ59284.1	0.0	1	1046	1	1046
QDO71487.1	0.0	1	1046	1	1049
QRQ48901.1	0.0	1	1045	1	1010
QUT44551.1	0.0	1	1045	1	1010

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6K5J_A	3.29e-64	60	573	11	532	Structureof a glycoside hydrolase family 3 beta-N-acetylglucosaminidase from Paenibacillus sp. str. FPU-7 [Paenibacillaceae]
3BMX_A	1.88e-58	54	425	36	446	Beta-N-hexosaminidase(YbbD) from Bacillus subtilis [Bacillus subtilis],3BMX_B Beta-N-hexosaminidase (YbbD) from Bacillus subtilis [Bacillus subtilis],3NVD_A Structure of YBBD in complex with pugnac [Bacillus subtilis],3NVD_B Structure of YBBD in complex with pugnac [Bacillus subtilis]
3LK6_A	5.41e-58	54	425	10	420	ChainA, Lipoprotein ybbD [Bacillus subtilis],3LK6_B Chain B, Lipoprotein ybbD [Bacillus subtilis],3LK6_C Chain C, Lipoprotein ybbD [Bacillus subtilis],3LK6_D Chain D, Lipoprotein ybbD [Bacillus subtilis]
4GYJ_A	9.51e-58	54	425	40	450	Crystalstructure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1) [Bacillus subtilis subsp. subtilis str. 168],4GYJ_B Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1) [Bacillus subtilis subsp. subtilis str. 168],4GYK_A Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1211) [Bacillus subtilis subsp. subtilis str. 168],4GYK_B Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1211) [Bacillus subtilis subsp. subtilis str. 168]
3SQL_A	1.03e-52	67	402	31	371	CrystalStructure of Glycoside Hydrolase from Synechococcus [Synechococcus sp. PCC 7002],3SQL_B Crystal Structure of Glycoside Hydrolase from Synechococcus [Synechococcus sp. PCC 7002],3SQM_A Crystal Structure of Glycoside Hydrolase from Synechococcus Complexed with N-acetyl-D-glucosamine [Synechococcus sp. PCC 7002],3SQM_B Crystal Structure of Glycoside Hydrolase from Synechococcus Complexed with N-acetyl-D-glucosamine [Synechococcus sp. PCC 7002],3SQM_C Crystal Structure of Glycoside Hydrolase from Synechococcus Complexed with N-acetyl-D-glucosamine [Synechococcus sp. PCC 7002],3SQM_D Crystal Structure of Glycoside Hydrolase from Synechococcus Complexed with N-acetyl-D-glucosamine [Synechococcus sp. PCC 7002]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P40406	1.03e-57	54	425	36	446	Beta-hexosaminidase OS=Bacillus subtilis (strain 168) OX=224308 GN=nagZ PE=1 SV=1
P48823	9.10e-46	86	460	55	458	Beta-hexosaminidase A OS=Pseudoalteromonas piscicida OX=43662 GN=cht60 PE=1 SV=1
P77619	6.03e-39	594	1023	30	400	Putative D-alanyl-D-alanine carboxypeptidase OS=Escherichia coli (strain K12) OX=83333 GN=yfeW PE=1 SV=2
Q8XBJ0	1.22e-37	594	1023	30	400	Putative D-alanyl-D-alanine carboxypeptidase OS=Escherichia coli O157:H7 OX=83334 GN=yfeW PE=3 SV=1
B5RCU8	2.59e-35	594	1028	30	405	Putative D-alanyl-D-alanine carboxypeptidase OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) OX=550538 GN=yfeW PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as LIPO

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000423	0.422795	0.576202	0.000204	0.000196	0.000166

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002455_00676.