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CAZyme Information: MGYG000002459_01202

You are here: Home > Sequence: MGYG000002459_01202

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Bifidobacterium animalis
Lineage Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Bifidobacteriaceae; Bifidobacterium; Bifidobacterium animalis
CAZyme ID MGYG000002459_01202
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
394 MGYG000002459_1|CGC18 41874.63 7.4776
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002459 1958651 Isolate China Asia
Gene Location Start: 1385695;  End: 1386879  Strand: -

Full Sequence      Download help

MSSNTQHRIM  LAGGGTAGHV  NPLLAVADAI  RCLDPDADII  ALGTAVGLEA  DLVPQAGYQL60
ETIEKVPFPR  RPNRAALEFP  RKWKAEKAKV  MQYLEHQGTQ  VVVGFGGYAS  APAYSAAHRL120
GIPVVIHEQN  ARAGMANKLG  ARWAQFIGTA  YDATGLKPAK  DGGIERVGLP  LRPAIANLAE180
ELERDREGAR  TRNAAELGLD  PNRPIIVVTG  GSLGAQSINR  AVAGSARQLT  EVAQIVHLTG240
KGKIDEVRDL  VVQNAGADVL  TGLGEESRPG  RNYHVAQYLE  RIDKAFACAD  LVICRSGAGT300
VSELTALGLP  AVYVPLPIGN  GEQRFNALPV  SDAGGGIIVD  DRSFTSQWVS  AQVPGLLANP360
ARLRSYGEHA  WQYGIRDAAD  RMAREILSIA  DARV394

Enzyme Prediction      help

No EC number prediction in MGYG000002459_01202.

CAZyme Signature Domains help

Created with Snap1939597898118137157177197216236256275295315334354374206378GT28
Family Start End Evalue family coverage
GT28 206 378 3.3e-46 0.9872611464968153

CDD Domains      download full data without filtering help

Created with Snap19395978981181371571771972162362562752953153343543748390murG8385GT28_MurG8390MurG8386murG205382Glyco_tran_28_C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 4.45e-121 8 390 3 355
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 1.21e-101 8 385 1 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 1.87e-86 8 390 2 355
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 2.50e-81 8 386 2 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
pfam04101 Glyco_tran_28_C 2.93e-35 205 382 1 166
Glycosyltransferase family 28 C-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.

CAZyme Hits      help

Created with Snap19395978981181371571771972162362562752953153343543741394ACS48121.1|GT281394QEG48676.1|GT281394QBA08939.1|GT281394QYU55480.1|GT281394ADG33750.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
ACS48121.1 1.65e-285 1 394 1 394
QEG48676.1 1.65e-285 1 394 1 394
QBA08939.1 1.65e-285 1 394 1 394
QYU55480.1 1.65e-285 1 394 1 394
ADG33750.1 1.65e-285 1 394 1 394

PDB Hits      download full data without filtering help

Created with Snap193959789811813715717719721623625627529531533435437413921F0K_A93903S2U_A33477D1I_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
1F0K_A 3.87e-46 1 392 1 356
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
3S2U_A 9.58e-36 9 390 5 355
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
7D1I_A 9.50e-35 3 347 7 324
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]

Swiss-Prot Hits      download full data without filtering help

Created with Snap19395978981181371571771972162362562752953153343543741391sp|B3DQN1|MURG_BIFLD1391sp|Q8CY50|MURG_BIFLO3391sp|A1A2E9|MURG_BIFAA1391sp|B7GQ78|MURG_BIFLS10382sp|Q6AE64|MURG_LEIXX
Hit ID E-Value Query Start Query End Hit Start Hit End Description
B3DQN1 4.29e-187 1 391 1 390
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bifidobacterium longum (strain DJO10A) OX=205913 GN=murG PE=3 SV=1
Q8CY50 4.29e-187 1 391 1 390
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bifidobacterium longum (strain NCC 2705) OX=206672 GN=murG PE=3 SV=1
A1A2E9 6.08e-187 3 391 2 389
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 / E194a) OX=367928 GN=murG PE=3 SV=1
B7GQ78 2.47e-186 1 391 1 390
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bifidobacterium longum subsp. infantis (strain ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12) OX=391904 GN=murG PE=3 SV=1
Q6AE64 2.87e-110 10 382 5 347
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Leifsonia xyli subsp. xyli (strain CTCB07) OX=281090 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000059 0.000001 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002459_01202.