dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: MGYG000002463_02504

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Basic Information help

Species

Pseudomonas aeruginosa

Lineage

Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas; Pseudomonas aeruginosa

CAZyme ID

MGYG000002463_02504

CAZy Family

GT4

CAZyme Description

Alginate biosynthesis protein AlgA

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
481	MGYG000002463_13\|CGC3	53169.27	5.5476

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002463	6750396	Isolate	Brazil	South America

Gene Location

Start: 221444; End: 222889 Strand: -

Full Sequence Download help

Enzyme Prediction help

No EC number prediction in MGYG000002463_02504.

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG0836	CpsB	0.0	1	332	2	333	Mannose-1-phosphate guanylyltransferase [Cell wall/membrane/envelope biogenesis].
TIGR01479	GMP_PMI	0.0	1	468	1	468	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. This enzyme is known to be bifunctional, as both mannose-6-phosphate isomerase (EC 5.3.1.8) (PMI) and mannose-1-phosphate guanylyltransferase (EC 2.7.7.22) in Pseudomonas aeruginosa, Xanthomonas campestris, and Gluconacetobacter xylinus. The literature on the enzyme from E. coli attributes mannose-6-phosphate isomerase activity to an adjacent gene, but the present sequence has not been shown to lack the activity. The PMI domain is C-terminal. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]
PRK15460	cpsB	0.0	1	468	6	477	mannose-1-phosphate guanyltransferase; Provisional
cd02509	GDP-M1P_Guanylyltransferase	1.16e-140	1	277	1	274	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose. GDP-mannose-1-phosphate guanylyltransferase, also called GDP-mannose pyrophosphorylase (GDP-MP), catalyzes the formation of GDP-Mannose from mannose-1-phosphate and GTP. Mannose is a key monosaccharide for glycosylation of proteins and lipids. GDP-Mannose is the activated donor for mannosylation of various biomolecules. This enzyme is known to be bifunctional, as both mannose-6-phosphate isomerase and mannose-1-phosphate guanylyltransferase. This CD covers the N-terminal GDP-mannose-1-phosphate guanylyltransferase domain, whereas the isomerase function is located at the C-terminal half. GDP-MP is a member of the nucleotidyltransferase family of enzymes.
pfam01050	MannoseP_isomer	1.95e-102	314	464	1	151	Mannose-6-phosphate isomerase. All of the members of this Pfam entry belong to family 2 of the mannose-6-phosphate isomerases. The type II phosphomannose isomerases are bifunctional enzymes. This Pfam entry covers the isomerase domain. The guanosine diphospho-D-mannose pyrophosphorylase domain is in another Pfam entry, see pfam00483.

CAZyme Hits help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AGN91810.2	2.32e-167	1	467	2	472
ACC75758.1	2.04e-54	1	273	32	312
BCF92878.1	1.72e-53	1	291	29	327
AFM26073.1	1.13e-24	355	471	336	452
QCQ21102.1	2.89e-24	359	468	340	449

PDB Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2X5S_A	7.83e-58	1	346	2	332	Crystalstructure of T. maritima GDP-mannose pyrophosphorylase in apo state. [Thermotoga maritima MSB8],2X5S_B Crystal structure of T. maritima GDP-mannose pyrophosphorylase in apo state. [Thermotoga maritima MSB8],2X5Z_A Crystal structure of T. maritima GDP-mannose pyrophosphorylase in complex with GDP-mannose. [Thermotoga maritima MSB8],2X5Z_B Crystal structure of T. maritima GDP-mannose pyrophosphorylase in complex with GDP-mannose. [Thermotoga maritima MSB8],2X60_A Crystal structure of T. maritima GDP-mannose pyrophosphorylase in complex with GTP. [Thermotoga maritima MSB8],2X60_B Crystal structure of T. maritima GDP-mannose pyrophosphorylase in complex with GTP. [Thermotoga maritima MSB8],2X65_A Crystal structure of T. maritima GDP-mannose pyrophosphorylase in complex with mannose-1-phosphate. [Thermotoga maritima MSB8],2X65_B Crystal structure of T. maritima GDP-mannose pyrophosphorylase in complex with mannose-1-phosphate. [Thermotoga maritima MSB8]
2QH5_A	9.92e-58	4	290	8	288	Crystalstructure of mannose-6-phosphate isomerase from Helicobacter pylori [Helicobacter pylori 26695],2QH5_B Crystal structure of mannose-6-phosphate isomerase from Helicobacter pylori [Helicobacter pylori 26695]
2CU2_A	8.56e-57	4	349	6	336	Crystalstructure of mannose-1-phosphate geranyltransferase from Thermus thermophilus HB8 [Thermus thermophilus HB8]

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P07874	0.0	1	481	1	481	Alginate biosynthesis protein AlgA OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964 GN=algA PE=1 SV=3
Q88ND5	1.75e-294	1	472	2	473	Alginate biosynthesis protein AlgA OS=Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) OX=160488 GN=algA PE=3 SV=1
Q887Q9	5.73e-288	1	469	1	469	Alginate biosynthesis protein AlgA OS=Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000) OX=223283 GN=algA PE=3 SV=1
P59785	2.87e-281	1	469	1	469	Alginate biosynthesis protein AlgA OS=Pseudomonas fluorescens OX=294 GN=algA PE=3 SV=1
B0RVK6	6.88e-198	1	469	4	467	Xanthan biosynthesis protein XanB OS=Xanthomonas campestris pv. campestris (strain B100) OX=509169 GN=xanB PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000095	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM Annotations help

There is no transmembrane helices in MGYG000002463_02504.