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CAZyme Information: MGYG000002463_03417
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Pseudomonas aeruginosa | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas; Pseudomonas aeruginosa | |||||||||||
| CAZyme ID | MGYG000002463_03417 | |||||||||||
| CAZy Family | GT2 | |||||||||||
| CAZyme Description | Linear gramicidin synthase subunit D | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 75966; End: 80519 Strand: - | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| PRK12316 | PRK12316 | 0.0 | 184 | 1241 | 4067 | 5136 | peptide synthase; Provisional |
| PRK12316 | PRK12316 | 0.0 | 226 | 1331 | 52 | 1164 | peptide synthase; Provisional |
| PRK12316 | PRK12316 | 0.0 | 169 | 1296 | 1494 | 2643 | peptide synthase; Provisional |
| PRK05691 | PRK05691 | 0.0 | 202 | 1249 | 3236 | 4313 | peptide synthase; Validated |
| cd05930 | A_NRPS | 0.0 | 676 | 1158 | 1 | 444 | The adenylation domain of nonribosomal peptide synthetases (NRPS). The adenylation (A) domain of NRPS recognizes a specific amino acid or hydroxy acid and activates it as an (amino) acyl adenylate by hydrolysis of ATP. The activated acyl moiety then forms a thioester bond to the enzyme-bound cofactor phosphopantetheine of a peptidyl carrier protein domain. NRPSs are large multifunctional enzymes which synthesize many therapeutically useful peptides in bacteria and fungi via a template-directed, nucleic acid independent nonribosomal mechanism. These natural products include antibiotics, immunosuppressants, plant and animal toxins, and enzyme inhibitors. NRPS has a distinct modular structure in which each module is responsible for the recognition, activation, and in some cases, modification of a single amino acid residue of the final peptide product. The modules can be subdivided into domains that catalyze specific biochemical reactions. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QND46664.1 | 8.60e-212 | 2 | 1363 | 1403 | 2784 |
| BAZ00088.1 | 3.03e-162 | 115 | 1367 | 2142 | 3417 |
| BAZ75991.1 | 3.03e-162 | 115 | 1367 | 2142 | 3417 |
| BAY30132.1 | 1.96e-160 | 115 | 1367 | 2144 | 3419 |
| AFZ04852.1 | 3.39e-122 | 385 | 1368 | 305 | 1313 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6MFZ_A | 9.63e-171 | 2 | 1243 | 580 | 1796 | Crystalstructure of dimodular LgrA in a condensation state [Brevibacillus parabrevis],6MFZ_B Crystal structure of dimodular LgrA in a condensation state [Brevibacillus parabrevis] |
| 2VSQ_A | 5.29e-169 | 218 | 1365 | 7 | 1149 | Structureof surfactin A synthetase C (SrfA-C), a nonribosomal peptide synthetase termination module [Bacillus subtilis] |
| 6MFY_A | 1.02e-147 | 2 | 1168 | 580 | 1722 | Crystalstructure of a 5-domain construct of LgrA in the substrate donation state [Brevibacillus parabrevis],6MG0_A Crystal structure of a 5-domain construct of LgrA in the thiolation state [Brevibacillus parabrevis],6MG0_B Crystal structure of a 5-domain construct of LgrA in the thiolation state [Brevibacillus parabrevis] |
| 6P1J_A | 6.09e-128 | 224 | 1158 | 6 | 964 | Thestructure of condensation and adenylation domains of teixobactin-producing nonribosomal peptide synthetase Txo2 serine module [Eleftheria terrae],6P1J_B The structure of condensation and adenylation domains of teixobactin-producing nonribosomal peptide synthetase Txo2 serine module [Eleftheria terrae] |
| 5JA1_A | 4.67e-116 | 257 | 1379 | 41 | 1178 | EntF,a Terminal Nonribosomal Peptide Synthetase Module Bound to the MbtH-Like Protein YbdZ [Escherichia coli K-12],5JA2_A EntF, a Terminal Nonribosomal Peptide Synthetase Module Bound to the non-Native MbtH-Like Protein PA2412 [Escherichia coli K-12],5T3D_A Crystal structure of holo-EntF a nonribosomal peptide synthetase in the thioester-forming conformation [Escherichia coli K-12] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q70LM4 | 1.29e-211 | 220 | 1243 | 4 | 1032 | Linear gramicidin synthase subunit D OS=Brevibacillus parabrevis OX=54914 GN=lgrD PE=1 SV=1 |
| Q70LM5 | 1.45e-211 | 220 | 1241 | 5183 | 6209 | Linear gramicidin synthase subunit C OS=Brevibacillus parabrevis OX=54914 GN=lgrC PE=3 SV=1 |
| P45745 | 7.89e-209 | 2 | 1387 | 848 | 2253 | Dimodular nonribosomal peptide synthase OS=Bacillus subtilis (strain 168) OX=224308 GN=dhbF PE=1 SV=4 |
| P0DUV3 | 1.42e-205 | 4 | 1364 | 4017 | 5404 | Malpicyclin synthetase OS=Mortierella alpina OX=64518 GN=mpcA PE=1 SV=1 |
| P0DUV4 | 2.60e-205 | 4 | 1364 | 4027 | 5414 | Malpibaldin synthetase OS=Mortierella alpina OX=64518 GN=mpbA PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000073 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |