CAZyme Information: MGYG000002463_05893

Basic Information

• Species: Pseudomonas aeruginosa
• Lineage: Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas; Pseudomonas aeruginosa
• CAZyme ID: MGYG000002463_05893
• CAZy Family: GT4
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
540	MGYG000002463_79|CGC2	60857.34	4.7654

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002463	6750396	Isolate	Brazil	South America

• Gene Location: Start: 50971; End: 52593 Strand: +

Full Sequence      

MNFILYSDINERSIGHNLGRPEYSYYFVLKAYRPILESLGQVHLVQSTDEVDPLYRQLHE
QGEDCLFLSFTPPHKAARDLQCPMLCVVAWEFESIPDVAWDGDPAQDWSQVLAGHGAAIT
LSEQTARAVRRVLGEDFPVLALPTPIWEEFAAIRQQGERNPVKSGETLQLKGCVIDSRLL
GLSADGLIAPIMEETEDEILEVLPETPAEPEPVPEPEPEPEPVPLDWRRRLVISKHYLLL
WYREAVSDLVPIPVRRWLFRHLRQPLPPPPTALETLPEPLPQAIEPMPPAEPEHPPALLP
DVDQHQQVVVDGVVYVSVFNPLDGRKNWHQLISAFCWAFRDTSDATLVLKMTQSDLTTYH
VELLTLLSQLSPFACRVIALHGYLDAAEYARLYGAASYYVNASRCEGLCLPLMEFMSCGT
PAIAPDHSAMADYMDAQVGFVVRSSQEPAAWPQDSRRLYSTRRYRPSWESLKEAYLESYR
VAREQPERYRQLSTAANQRMRGYCAGDVVRQRLEPFLSARKATPAPGVELAATATGNVPC

Enzyme Prediction     

No EC number prediction in MGYG000002463_05893.

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG0438	RfaB	2.25e-15	322	480	208	375	Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis].
cd03801	GT4_PimA-like	4.71e-10	322	480	201	366	phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.
cd01635	Glycosyltransferase_GTB-type	3.26e-09	322	433	119	225	glycosyltransferase family 1 and related proteins with GTB topology. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
pfam13692	Glyco_trans_1_4	5.72e-09	366	451	47	128	Glycosyl transferases group 1.
cd03809	GT4_MtfB-like	3.55e-08	322	430	201	304	glycosyltransferases MtfB, WbpX, and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AZN61262.1	0.0	1	540	1	540
AYR15918.1	0.0	1	540	1	540
AZN54772.1	0.0	1	540	1	540
AZN49506.1	0.0	1	540	1	540
QCQ89552.1	0.0	1	540	1	540

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000071	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002463_05893.