CAZyme Information: MGYG000002470_00435

Basic Information

• Species: Bacteroides intestinalis
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides intestinalis
• CAZyme ID: MGYG000002470_00435
• CAZy Family: GH146
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
789		89890.35	6.9696

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002470	5774847	Isolate	Ireland	Europe

• Gene Location: Start: 583509; End: 585878 Strand: -

Full Sequence      

MKSILITYLFLFCFLLTGKAQTQQEVSYFPLQDVKLLESPFLQAQQTDLHYIMAMEPDRL
LAPFLREAGLTPKAPSYTNWENTGLDGHIGGHYISALSMMYAATGDTAIYNRLNYMLAEL
HRAQQAVGTGFIGGTPGSLQLWKEIKAGNIRAGGFDLNGKWVPLYNIHKTYAGLRDAYLY
AGSNLAREMLIALTDWMIDITAGLTDQQMQDMLRSEHGGLNETFADVAEITGDKKYLELA
RRFSHKLILDPLVKDEDRLTGMHANTQIPKVIGYKRIADLAQDDKDWNHASEWDHAARFF
WNTVVNHRSVCIGGNSVREHFHPADNFTSMLNDVQGPETCNTYNMLRLTKMLYQTSPDIR
FADYYERALYNHILASQQPEKGGFVYFTPMRPGHYRVYSQPETSMWCCVGSGLENHTKYG
EFIYAHTNDTLYVNLFIPSRLTWQEKKVTLVQETRFPDEEQIRFRVEKSRKKAFSLKLRY
PSWAKGASVSVNGKVQETNAQPGEYLTIHRKWKAGDEITLNMPMQVALEQIPDRENFYAF
MYGPIVLASPTGTENMDGLYADDSRGGHIAHGKQISMQEIPMLIGSAASLPQSLRRINDD
LVAFTYTGSVYPAQKEALKLIPFFRLHDSRYAVYFHQVTEAEVESIRKEVALSERKAMEL
ANQTVDLIFPGEQQPESDHGILYEQAETGINKDRHFRRAKGWFSYNLKVKEEAAQLMITI
RKENHNKVAILLNNEKLTVSPTISKPDKEGFITLCYSLPQKLSAGSYPIRFSPDGTEWTP
AIYEVRLLK

Enzyme Prediction     

EC	3.2.1.185

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH146	33	548	1.8e-220	0.9980119284294234

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam07944	Glyco_hydro_127	0.0	33	548	1	503	Beta-L-arabinofuranosidase, GH127. One member of this family, from Bidobacterium longicum, UniProtKB:E8MGH8, has been characterized as an unusual beta-L-arabinofuranosidase enzyme, EC:3.2.1.185. It rleases l-arabinose from the l-arabinofuranose (Araf)-beta1,2-Araf disaccharide and also transglycosylates 1-alkanols with retention of the anomeric configuration. Terminal beta-l-arabinofuranosyl residues have been found in arabinogalactan proteins from a mumber of different plantt species. beta-l-Arabinofuranosyl linkages with 1-4 arabinofuranosides are also found in the sugar chains of extensin and solanaceous lectins, hydroxyproline (Hyp)2-rich glycoproteins that are widely observed in plant cell wall fractions. The critical residue for catalytic activity is Glu-338, in a ET/SCAS sequence context.
COG3533	COG3533	2.33e-136	31	624	9	571	Uncharacterized conserved protein, DUF1680 family [Function unknown].
pfam16375	DUF4986	1.95e-37	552	635	1	84	Domain of unknown function. This family around 150 residues locates in the C-terminal of some uncharacterized proteins in various Bacteroides and Bacillus species. The function of this family remains unknown.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QDO70922.1	0.0	1	789	1	789
ALJ58196.1	0.0	1	789	1	782
QUT90786.1	0.0	1	789	1	782
QUT46350.1	0.0	1	789	1	781
QRQ48086.1	0.0	1	789	1	781

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5OPJ_A	0.0	18	789	17	802	Beta-L-arabinofuranosidase[Bacteroides thetaiotaomicron]
6YQH_AAA	0.0	18	789	17	802	ChainAAA, Acetyl-CoA carboxylase, biotin carboxylase [Bacteroides thetaiotaomicron VPI-5482]
4QJY_A	2.02e-22	160	546	131	558	Crystalstructure of native Ara127N, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QJY_B Crystal structure of native Ara127N, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus]
6EX6_A	4.68e-22	231	524	206	517	TheGH127, Beta-arabinofuranosidase, BT3674 [Bacteroides thetaiotaomicron VPI-5482],6EX6_B The GH127, Beta-arabinofuranosidase, BT3674 [Bacteroides thetaiotaomicron VPI-5482]
4QK0_A	5.79e-21	229	546	203	558	Crystalstructure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_B Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_C Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_D Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000306	0.998853	0.000366	0.000171	0.000156	0.000140

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002470_00435.