CAZyme Information: MGYG000002473_00442

Basic Information

• Species: Victivallis vadensis
• Lineage: Bacteria; Verrucomicrobiota; Lentisphaeria; Victivallales; Victivallaceae; Victivallis; Victivallis vadensis
• CAZyme ID: MGYG000002473_00442
• CAZy Family: GH39
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
997		110506.08	8.7491

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002473	4576885	Isolate	not provided	not provided

• Gene Location: Start: 12452; End: 15445 Strand: +

Full Sequence      

MRLLLLFMLAVLAPVLRGGEIFDFARLSDRIELVHYQKGSAAKVGKIDGRDALELFFDPA
LNSWNTIAIKNYQRPRLPLFRKCRIALEVWLPRNHAVRSVNLELCDSTGEMLQYPGVVSA
QDHGWRKVAWEIDTALRAPHSWGGKKNAVPDGKTMIRNFSCSFRPGGAAGSLAFGKVFLE
VEEAPLEFGVATGNGFPVITRGREAEFGISLKNGNPVVRRGKAKWEISTANGDRLSAGED
DWEVAPRSEKVIPLPAPAAYGLYDLRVNIDGEQERKFRFGYMAPAGPVDGPIRGFVLGVC
EHPESLSDEEAEVWTRSAALCGARVIRGAGSWTGIEWRKGHPDYHVEDTMVERLERYHMK
MSLLLLGTPGWAVAKEWKPLMPEKKYWPMPDLDAWQKYVRTLASRWGDRLYSLEVWNEPD
LRTNGNFTSREYFKMLKAANDAAKSVNPGLQIQSGGLAGIDLPASISADPRYAWKLLKDE
AANYDVFALHNHQVYLGYEDMVGRFLKYRREARTGKPWYANETAITSSTVGDEKQAHTLF
QKIIYTMSLMNRGAIGYNWYNLVEKTKYPAGHPERHFGLLTPELEPKAAYLAYNTVAGHF
REAVPEREFSGPGDSFRLYCFKAANGDYLVPGWSVSDKGNKAILLSGITGRAVRVDLNGN
LEPLAATNGGVLFTLSETPAFVRISGQGKAPLCMGAPLELPDTLILRGREVTTLKAVLRN
SGPKAVSLNVVADAPRGVQVRPRSIREPLAAGASRQVEFSVRAQDSFERGNLRFLVNPGM
GVVSVRLERAVRLGDAPGLKHDLFLGERSQLVSMYPSAVETTHLQWQGPDDLSGKFFLSA
RNQVLAIRCDVTDDRHRQRFSGSEIWQNDSLQIALTLPGQNTFWELGAALADSGKAVGYC
WRAPAGFHAEQAIGKIGVEVTRDEARKLTRYILKIPFDAIGLTGEKLGAGIRFNALINDC
DETATRESYLRLAPGLGDGAASPELSVLIYRQEAEQK

Enzyme Prediction     

No EC number prediction in MGYG000002473_00442.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH39	347	613	2e-21	0.6612529002320185

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd09621	CBM9_like_5	5.03e-64	801	990	1	188	DOMON-like type 9 carbohydrate binding module. Family 9 carbohydrate-binding modules (CBM9) play a role in the microbial degradation of cellulose and hemicellulose (materials found in plants). The domain has previously been called cellulose-binding domain. The polysaccharide binding sites of CBMs with available 3D structure have been found to be either flat surfaces with interactions formed by predominantly aromatic residues (tryptophan and tyrosine), or extended shallow grooves. CBM9 domains found in this uncharacterized heterogeneous subfamily are often located at the C-terminus of longer proteins and may co-occur with various other functional domains such as glycosyl hydrolases. The CBM9 module in these architectures may be involved in binding to carbohydrates.
cd09619	CBM9_like_4	3.22e-11	826	985	30	185	DOMON-like type 9 carbohydrate binding module. Family 9 carbohydrate-binding modules (CBM9) play a role in the microbial degradation of cellulose and hemicellulose (materials found in plants). The domain has previously been called cellulose-binding domain. The polysaccharide binding sites of CBMs with available 3D structure have been found to be either flat surfaces with interactions formed by predominantly aromatic residues (tryptophan and tyrosine), or extended shallow grooves. CBM9 domains found in this uncharacterized heterogeneous subfamily are often located at the C-terminus of longer proteins and may co-occur with various other domains.
cd00241	DOMON_like	1.50e-08	826	959	12	146	Domon-like ligand-binding domains. DOMON-like domains can be found in all three kindgoms of life and are a diverse group of ligand binding domains that have been shown to interact with sugars and hemes. DOMON domains were initially thought to confer protein-protein interactions. They were subsequently found as a heme-binding motif in cellobiose dehydrogenase, an extracellular fungal oxidoreductase that degrades both lignin and cellulose, and in ethylbenzene dehydrogenase, an enzyme that aids in the anaerobic degradation of hydrocarbons. The domain interacts with sugars in the type 9 carbohydrate binding modules (CBM9), which are present in a variety of glycosyl hydrolases, and it can also be found at the N-terminus of sensor histidine kinases.
pfam01229	Glyco_hydro_39	1.28e-06	388	459	120	198	Glycosyl hydrolases family 39.
pfam06452	CBM9_1	7.09e-04	816	970	12	160	Carbohydrate family 9 binding domain-like. CBM9_1 is a C-terminal domain on bacterial xylanase proteins, and it is tandemly repeated in a number of family-members. The CBM9 module binds to amorphous and crystalline cellulose and a range of soluble di- and monosaccharides as well as to cello- and xylo- oligomers of different degrees of polymerization. Comparison of the glucose and cellobiose complexes during crystallisation reveals surprising differences in binding of these two substrates by CBM9-2. Cellobiose was found to bind in a distinct orientation from glucose, while still maintaining optimal stacking and electrostatic interactions with the reducing end sugar.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AHF94342.1	1.86e-174	19	992	46	1034
AHF90198.1	2.50e-135	48	984	52	998
AVM46276.1	9.22e-99	186	978	328	1124
AVM44759.1	9.71e-99	284	978	258	952
AVM47149.1	1.18e-98	166	990	469	1306

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000213	0.999183	0.000161	0.000142	0.000140	0.000135

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002473_00442.