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CAZyme Information: MGYG000002474_03178
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Rahnella variigena | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Rahnella; Rahnella variigena | |||||||||||
| CAZyme ID | MGYG000002474_03178 | |||||||||||
| CAZy Family | GT56 | |||||||||||
| CAZyme Description | TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 31866; End: 32948 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT56 | 1 | 353 | 1.7e-160 | 0.9943977591036415 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| PRK02797 | PRK02797 | 0.0 | 40 | 360 | 1 | 322 | TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase. |
| pfam07429 | Glyco_transf_56 | 0.0 | 1 | 357 | 1 | 358 | 4-alpha-L-fucosyltransferase glycosyl transferase group 56. This family contains the bacterial enzyme 4-alpha-L-fucosyltransferase (Fuc4NAc transferase) (EC 2.4.1.-) (approximately 360 residues long). This catalyzes the synthesis of Fuc4NAc-ManNAcA-GlcNAc-PP-Und (lipid III) as part of the biosynthetic pathway of enterobacterial common antigen (ECA), a polysaccharide comprised of the trisaccharide repeat unit Fuc4NAc-ManNAcA-GlcNAc. |
| cd07534 | HAD_CAP | 0.002 | 251 | 349 | 78 | 196 | molecular class C acid phosphatases, similar to Haemophilus influenzae e (P4) acid phosphatase; belongs to the haloacid dehalogenase-like hydrolase superfamily. Molecular class C acid phosphatases (CAPs) are nonspecific acid phosphatases with generally broad substrate specificity and optimum activity at neutral to acidic pH. Members include Haemophilus influenzae lipoprotein e (P4), Elizabethkingia meningosepticum OlpA, Helicobacter pylori HppA, Enterobacter sp. 4 acid phosphatase PhoI, and Streptococcus pyogenes M1 GAS LppC. Lipoprotein e (P4) exhibits phosphomonoesterase activity with aryl phosphate substrates including nicotinamide mononucleotide (NMN), tyrosine phosphate, phenyl phosphate, p-nitrophenyl phosphate, and 4-methylumbelliferyl phosphate. The role of P4 in NAD+ uptake appears to be the dephosphorylation of NMN to nicotinamide riboside, which is then taken up by the organism. Elizabethkingia meningosepticum OlpA is a broad-spectrum nucleotidase with preference for 5'-nucleotides, it efficiently hydrolyzes nucleotide monophosphates, with a strong preference for 5'-nucleotides and for 3'-AMP; OlpA can also hydrolyze sugar phosphates and beta-glycerol phosphate, although with a lower efficiency. Helicobacter pylori HppA is also a 5' nucleotidase. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QLK59451.1 | 1.09e-250 | 1 | 360 | 1 | 360 |
| AVF36660.1 | 6.02e-248 | 1 | 360 | 1 | 360 |
| QQN33856.1 | 1.22e-247 | 1 | 360 | 1 | 360 |
| AZP48616.1 | 1.22e-247 | 1 | 360 | 1 | 360 |
| AZP44280.1 | 1.22e-247 | 1 | 360 | 1 | 360 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| A8G840 | 9.39e-198 | 1 | 360 | 1 | 361 | TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase OS=Serratia proteamaculans (strain 568) OX=399741 GN=wecF PE=3 SV=1 |
| B2K058 | 5.71e-192 | 1 | 358 | 1 | 359 | TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) OX=502801 GN=wecF PE=3 SV=1 |
| Q66G07 | 5.71e-192 | 1 | 358 | 1 | 359 | TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase OS=Yersinia pseudotuberculosis serotype I (strain IP32953) OX=273123 GN=wecF PE=3 SV=1 |
| Q1CBP2 | 8.10e-192 | 1 | 358 | 1 | 359 | TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase OS=Yersinia pestis bv. Antiqua (strain Antiqua) OX=360102 GN=wecF PE=3 SV=1 |
| A9R8I9 | 8.10e-192 | 1 | 358 | 1 | 359 | TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase OS=Yersinia pestis bv. Antiqua (strain Angola) OX=349746 GN=wecF PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000047 | 0.000006 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |