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CAZyme Information: MGYG000002477_04095

You are here: Home > Sequence: MGYG000002477_04095

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Citrobacter_A amalonaticus
Lineage Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Citrobacter_A; Citrobacter_A amalonaticus
CAZyme ID MGYG000002477_04095
CAZy Family AA3
CAZyme Description Oxygen-dependent choline dehydrogenase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
558 MGYG000002477_2|CGC44 61627.66 6.9056
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002477 5083867 Isolate United States North America
Gene Location Start: 4103682;  End: 4105358  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000002477_04095.

CAZyme Signature Domains help

Family Start End Evalue family coverage
AA3 2 532 1.2e-162 0.9929577464788732

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG2303 BetA 0.0 1 538 6 540
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only].
PRK02106 PRK02106 0.0 1 558 4 558
choline dehydrogenase; Validated
TIGR01810 betA 0.0 4 537 1 532
choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli, Staphylococcus xylosus, and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified. [Cellular processes, Adaptations to atypical conditions]
pfam00732 GMC_oxred_N 4.42e-71 73 301 15 218
GMC oxidoreductase. This family of proteins bind FAD as a cofactor.
pfam05199 GMC_oxred_C 5.08e-46 393 527 3 143
GMC oxidoreductase. This domain found associated with pfam00732.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
CAB3230510.1 2.87e-186 5 546 27 570
AWP09430.1 1.35e-180 3 545 20 564
ANI26486.1 3.65e-180 3 545 71 615
CAG5086058.1 6.63e-152 3 547 15 579
CAG5089487.1 3.20e-151 3 537 17 564

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3LJP_A 1.55e-83 3 532 14 527
ChainA, Choline oxidase [Arthrobacter globiformis],3LJP_B Chain B, Choline oxidase [Arthrobacter globiformis]
2JBV_A 6.00e-83 3 532 14 527
Crystalstructure of choline oxidase reveals insights into the catalytic mechanism [Arthrobacter globiformis],2JBV_B Crystal structure of choline oxidase reveals insights into the catalytic mechanism [Arthrobacter globiformis],4MJW_A Crystal Structure of Choline Oxidase in Complex with the Reaction Product Glycine Betaine [Arthrobacter globiformis],4MJW_B Crystal Structure of Choline Oxidase in Complex with the Reaction Product Glycine Betaine [Arthrobacter globiformis]
3NNE_A 6.00e-83 3 532 14 527
Crystalstructure of choline oxidase S101A mutant [Arthrobacter globiformis],3NNE_B Crystal structure of choline oxidase S101A mutant [Arthrobacter globiformis],3NNE_C Crystal structure of choline oxidase S101A mutant [Arthrobacter globiformis],3NNE_D Crystal structure of choline oxidase S101A mutant [Arthrobacter globiformis],3NNE_E Crystal structure of choline oxidase S101A mutant [Arthrobacter globiformis],3NNE_F Crystal structure of choline oxidase S101A mutant [Arthrobacter globiformis],3NNE_G Crystal structure of choline oxidase S101A mutant [Arthrobacter globiformis],3NNE_H Crystal structure of choline oxidase S101A mutant [Arthrobacter globiformis]
6ZH7_A 2.59e-76 3 542 8 571
ChainA, Fatty acid photodecarboxylase, chloroplastic [Chlorella variabilis],6ZH7_B Chain B, Fatty acid photodecarboxylase, chloroplastic [Chlorella variabilis]
6YRU_AAA 2.59e-76 3 542 8 571
ChainAAA, Fatty acid Photodecarboxylase [Chlorella variabilis],6YRV_AAA Chain AAA, Fatty acid Photodecarboxylase [Chlorella variabilis],6YRX_AAA Chain AAA, Fatty acid Photodecarboxylase [Chlorella variabilis],6YRZ_AAA Chain AAA, Fatty acid photodecarboxylase, chloroplastic [Chlorella variabilis]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
B7N8L3 0.0 1 553 1 553
Oxygen-dependent choline dehydrogenase OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) OX=585056 GN=betA PE=3 SV=1
C6DKY4 0.0 1 554 1 552
Oxygen-dependent choline dehydrogenase OS=Pectobacterium carotovorum subsp. carotovorum (strain PC1) OX=561230 GN=betA PE=3 SV=1
B7V5R3 0.0 3 553 5 555
Oxygen-dependent choline dehydrogenase OS=Pseudomonas aeruginosa (strain LESB58) OX=557722 GN=betA PE=3 SV=1
B7UJG4 0.0 1 553 1 553
Oxygen-dependent choline dehydrogenase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) OX=574521 GN=betA PE=3 SV=1
P17444 0.0 1 553 1 553
Oxygen-dependent choline dehydrogenase OS=Escherichia coli (strain K12) OX=83333 GN=betA PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000048 0.000013 0.000002 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002477_04095.