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CAZyme Information: MGYG000002480_01236
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Adlercreutzia celatus_A | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Actinobacteriota; Coriobacteriia; Coriobacteriales; Eggerthellaceae; Adlercreutzia; Adlercreutzia celatus_A | |||||||||||
| CAZyme ID | MGYG000002480_01236 | |||||||||||
| CAZy Family | GH25 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 34204; End: 37347 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH25 | 205 | 396 | 6.9e-43 | 0.9943502824858758 |
| GH73 | 880 | 1025 | 4.5e-25 | 0.96875 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd06414 | GH25_LytC-like | 5.14e-71 | 204 | 406 | 3 | 191 | The LytC lysozyme of Streptococcus pneumoniae is a bacterial cell wall hydrolase that cleaves the beta1-4-glycosydic bond located between the N-acetylmuramoyl-N-glucosaminyl residues of the cell wall polysaccharide chains. LytC is composed of a C-terminal glycosyl hydrolase family 25 (GH25) domain and an N-terminal choline-binding module (CBM) consisting of eleven homologous repeats that specifically recognizes the choline residues of pneumococcal lipoteichoic and teichoic acids. This domain arrangement is the reverse of the major pneumococcal autolysin, LytA, and the CPL-1-like lytic enzymes of the pneumococcal bacteriophages, in which the CBM (consisting of six repeats) is at the C-terminus. This model represents the C-terminal catalytic domain of the LytC-like enzymes. |
| COG4193 | LytD | 4.26e-51 | 825 | 1047 | 54 | 245 | Beta- N-acetylglucosaminidase [Carbohydrate transport and metabolism]. |
| cd00599 | GH25_muramidase | 5.16e-30 | 204 | 403 | 2 | 184 | Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. This family of muramidases contains a glycosyl hydrolase family 25 (GH25) catalytic domain and is found in bacteria, fungi, slime molds, round worms, protozoans and bacteriophages. The bacteriophage members are referred to as endolysins which are involved in lysing the host cell at the end of the replication cycle to allow release of mature phage particles. Endolysins are typically modular enzymes consisting of a catalytically active domain that hydrolyzes the peptidoglycan cell wall and a cell wall-binding domain that anchors the protein to the cell wall. Endolysins generally have narrow substrate specificities with either intra-species or intra-genus bacteriolytic activity. |
| COG5263 | COG5263 | 1.89e-24 | 424 | 763 | 25 | 309 | Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism]. |
| pfam01183 | Glyco_hydro_25 | 5.11e-24 | 205 | 396 | 1 | 180 | Glycosyl hydrolases family 25. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| BCA89043.1 | 2.67e-293 | 99 | 1047 | 111 | 1048 |
| BCS56855.1 | 5.30e-268 | 124 | 1047 | 140 | 1072 |
| BAK44097.1 | 1.09e-56 | 92 | 414 | 523 | 832 |
| AWY97591.1 | 2.01e-55 | 130 | 404 | 39 | 283 |
| BAN76666.1 | 7.19e-51 | 141 | 415 | 57 | 315 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6FXO_A | 3.54e-30 | 857 | 1047 | 73 | 244 | ChainA, Bifunctional autolysin [Staphylococcus aureus subsp. aureus Mu50] |
| 4PI7_A | 5.05e-29 | 866 | 1041 | 70 | 226 | ChainA, Autolysin E [Staphylococcus aureus subsp. aureus Mu50],4PI9_A Chain A, Autolysin E [Staphylococcus aureus subsp. aureus Mu50],4PIA_A Chain A, Autolysin E [Staphylococcus aureus subsp. aureus Mu50] |
| 4PI8_A | 3.19e-28 | 866 | 1041 | 70 | 226 | ChainA, Autolysin E [Staphylococcus aureus subsp. aureus Mu50] |
| 5WQW_A | 4.77e-26 | 790 | 1027 | 15 | 257 | X-raystructure of catalytic domain of autolysin from Clostridium perfringens [Clostridium perfringens str. 13] |
| 6FXP_A | 2.02e-25 | 884 | 1027 | 104 | 230 | ChainA, Uncharacterized protein [Staphylococcus aureus subsp. aureus Mu50],6FXP_B Chain B, Uncharacterized protein [Staphylococcus aureus subsp. aureus Mu50] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P39848 | 1.12e-31 | 826 | 1047 | 686 | 880 | Beta-N-acetylglucosaminidase OS=Bacillus subtilis (strain 168) OX=224308 GN=lytD PE=1 SV=1 |
| O33635 | 2.10e-27 | 857 | 1047 | 1164 | 1335 | Bifunctional autolysin OS=Staphylococcus epidermidis OX=1282 GN=atl PE=1 SV=1 |
| Q5HQB9 | 2.10e-27 | 857 | 1047 | 1164 | 1335 | Bifunctional autolysin OS=Staphylococcus epidermidis (strain ATCC 35984 / RP62A) OX=176279 GN=atl PE=3 SV=1 |
| Q8CPQ1 | 1.08e-26 | 857 | 1047 | 1164 | 1335 | Bifunctional autolysin OS=Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) OX=176280 GN=atl PE=3 SV=1 |
| Q99V41 | 1.78e-26 | 857 | 1047 | 1077 | 1248 | Bifunctional autolysin OS=Staphylococcus aureus (strain N315) OX=158879 GN=atl PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.002153 | 0.996501 | 0.000659 | 0.000222 | 0.000221 | 0.000211 |