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CAZyme Information: MGYG000002481_03276

You are here: Home > Sequence: MGYG000002481_03276

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Stenotrophomonas maltophilia_F
Lineage Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales; Xanthomonadaceae; Stenotrophomonas; Stenotrophomonas maltophilia_F
CAZyme ID MGYG000002481_03276
CAZy Family GT2
CAZyme Description Acetyl-coenzyme A synthetase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
647 MGYG000002481_132|CGC1 71661.06 5.5358
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002481 4867831 Isolate United States North America
Gene Location Start: 3669;  End: 5612  Strand: +

Full Sequence      Download help

MADIYPVDPQ  FAAKARIDKT  SYEQQYQASV  TDPDGFWGKA  AERLQWMRKP  TKIKNVSYDL60
SDFHIKWFED  GELNASVNCL  DRQLETRGDK  TALLFEPDGP  DAPAQHVTYR  ELYERTCRLG120
NALRNLGVKK  GDRVTIYLPM  IVDAAVAMLA  CARIGAIHSV  VFGGFAPNSI  ADRVSDCQSK180
LIITADEGLR  GGRRIPLKAN  VDAALKLPGT  NTVETVLVVR  HTGGAVDMQA  PRDRWFHDVV240
DSQPSTCEPE  RMNAEDPLFI  LYTSGSTGKP  KGVLHTTGGY  LLYAAYTHEA  VFDLREDDIY300
WCTADVGWVT  GHSYIVYGPL  ANGATSLMFE  GVPNYPDTSR  FWNVIDKHKV  TIFYTAPTAI360
RALMREGEEP  VKKTSRASLR  LLGSVGEPIN  PEAWRWYYEV  VGDSRCPIVD  TWWQTETGGI420
LISPLAGAMD  LKPGSATLPF  FGVQPALVNA  DGEIQDGPTE  GNLIIRDSWP  GQMRTVYGDH480
QRFIDTYFRT  YPGSYFTGDG  CRRDEDGYYW  ITGRVDDVIN  VSGHRIGTAE  VESALVSHPK540
VAEAAVVGFP  HDVKGQGIYA  YVTLVAEEAP  SDELQKELVA  WVRKEIGPIA  TPDHLQWAPG600
LPKTRSGKIM  RRILRKIAEN  APDQLGDTST  LADPSVVASL  VDERKVR647

Enzyme Prediction      help

No EC number prediction in MGYG000002481_03276.

CDD Domains      download full data without filtering help

Created with Snap32649712916119422625829132335538842045248551754958261422637PrpE4641PLN0265420635prpE15634AACS_like4645PRK00174
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd05967 PrpE 0.0 22 637 1 614
Propionyl-CoA synthetase (PrpE). EC 6.2.1.17: propanoate:CoA ligase (AMP-forming) or propionate#CoA ligase (PrpE) catalyzes the first step of the 2-methylcitric acid cycle for propionate catabolism. It activates propionate to propionyl-CoA in a two-step reaction, which proceeds through a propionyl-AMP intermediate and requires ATP and Mg2+. In Salmonella enterica, the PrpE protein is required for growth of Salmonella enterica on propionate and can substitute for the acetyl-CoA synthetase (Acs) enzyme during growth on acetate. PrpE can also activate acetate, 3HP, and butyrate to their corresponding CoA-thioesters, although with less efficiency.
PLN02654 PLN02654 0.0 4 641 14 661
acetate-CoA ligase
PRK10524 prpE 0.0 20 635 2 618
propionyl-CoA synthetase; Provisional
cd05968 AACS_like 0.0 15 634 2 610
Uncharacterized acyl-CoA synthetase subfamily similar to Acetoacetyl-CoA synthetase. This uncharacterized acyl-CoA synthetase family (EC 6.2.1.16, or acetoacetate#CoA ligase or acetoacetate:CoA ligase (AMP-forming)) is highly homologous to acetoacetyl-CoA synthetase. However, the proteins in this family exist in only bacteria and archaea. AACS is a cytosolic ligase that specifically activates acetoacetate to its coenzyme A ester by a two-step reaction. Acetoacetate first reacts with ATP to form an acyl-adenylate intermediate, which then reacts with CoA to produce an acyl-CoA ester. This is the first step of the mevalonate pathway of isoprenoid biosynthesis via isopentenyl diphosphate. Isoprenoids are a large class of compounds found in all living organisms.
PRK00174 PRK00174 0.0 4 645 1 634
acetyl-CoA synthetase; Provisional

CAZyme Hits      help

Created with Snap3264971291611942262582913233553884204524855175495826144641CAE6201330.1|GH14641CAE6201338.1|GH150614AFZ04852.1|GT283640AFY93865.1|GT299621QND46664.1|GT1
Hit ID E-Value Query Start Query End Hit Start Hit End
CAE6201330.1 9.54e-255 4 641 564 1210
CAE6201338.1 1.32e-254 4 641 575 1221
AFZ04852.1 6.30e-24 50 614 562 1074
AFY93865.1 2.30e-23 83 640 340 867
QND46664.1 2.23e-22 99 621 2086 2583

PDB Hits      download full data without filtering help

Created with Snap32649712916119422625829132335538842045248551754958261456452P2F_A56455JRH_A56452P2B_A56452P2Q_A56452P2J_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
2P2F_A 1.20e-311 5 645 7 646
ChainA, Acetyl-coenzyme A synthetase [Salmonella enterica subsp. enterica serovar Typhimurium],2P2F_B Chain B, Acetyl-coenzyme A synthetase [Salmonella enterica subsp. enterica serovar Typhimurium]
5JRH_A 1.61e-311 5 645 7 646
Crystalstructure of Salmonella enterica acetyl-CoA synthetase (Acs) in complex with cAMP and Coenzyme A [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],5JRH_B Crystal structure of Salmonella enterica acetyl-CoA synthetase (Acs) in complex with cAMP and Coenzyme A [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
2P2B_A 4.88e-311 5 645 7 646
ChainA, Acetyl-coenzyme A synthetase [Salmonella enterica subsp. enterica serovar Typhimurium],2P2B_B Chain B, Acetyl-coenzyme A synthetase [Salmonella enterica subsp. enterica serovar Typhimurium]
2P2Q_A 6.93e-311 5 645 7 646
ChainA, Acetyl-coenzyme A synthetase [Salmonella enterica subsp. enterica serovar Typhimurium],2P2Q_B Chain B, Acetyl-coenzyme A synthetase [Salmonella enterica subsp. enterica serovar Typhimurium]
2P2J_A 9.83e-311 5 645 7 646
ChainA, Acetyl-coenzyme A synthetase [Salmonella enterica subsp. enterica serovar Typhimurium],2P2J_B Chain B, Acetyl-coenzyme A synthetase [Salmonella enterica subsp. enterica serovar Typhimurium]

Swiss-Prot Hits      download full data without filtering help

Created with Snap3264971291611942262582913233553884204524855175495826144645sp|Q2YLH5|ACSA_BRUA21644sp|Q87C00|ACSA_XYLFT3647sp|Q6MNF1|ACSA_BDEBA1647sp|Q4UP35|ACSA_XANC84645sp|Q89WV5|ACSA_BRADU
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q2YLH5 0.0 4 645 5 648
Acetyl-coenzyme A synthetase OS=Brucella abortus (strain 2308) OX=359391 GN=acsA PE=3 SV=1
Q87C00 0.0 1 644 1 644
Acetyl-coenzyme A synthetase OS=Xylella fastidiosa (strain Temecula1 / ATCC 700964) OX=183190 GN=acsA PE=3 SV=1
Q6MNF1 0.0 3 647 4 645
Acetyl-coenzyme A synthetase OS=Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100) OX=264462 GN=acsA PE=3 SV=1
Q4UP35 0.0 1 647 1 647
Acetyl-coenzyme A synthetase OS=Xanthomonas campestris pv. campestris (strain 8004) OX=314565 GN=acsA PE=3 SV=1
Q89WV5 0.0 4 645 5 643
Acetyl-coenzyme A synthetase OS=Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110) OX=224911 GN=acsA PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000058 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002481_03276.