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CAZyme Information: MGYG000002494_03310
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Citrobacter_B koseri | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Citrobacter_B; Citrobacter_B koseri | |||||||||||
| CAZyme ID | MGYG000002494_03310 | |||||||||||
| CAZy Family | GT2 | |||||||||||
| CAZyme Description | Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 3232475; End: 3241966 Strand: + | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG3321 | PksD | 0.0 | 24 | 1046 | 1 | 993 | Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism]. |
| cd00833 | PKS | 0.0 | 27 | 447 | 1 | 421 | polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or more large multifunctional proteins and iterative type II PKSs, complexes of several monofunctional subunits. |
| cd19535 | Cyc_NRPS | 7.77e-166 | 1915 | 2341 | 1 | 423 | Cyc (heterocyclization) domain of nonribosomal peptide synthetases (NRPSs); belongs to the Condensation-domain family. Cyc (heterocyclization) domains catalyze two separate reactions in the creation of heterocyclized peptide products in nonribosomal peptide synthesis: amide bond formation followed by intramolecular cyclodehydration between a Cys, Ser, or Thr side chain and a carbonyl carbon on the peptide backbone to form a thiazoline, oxazoline, or methyloxazoline ring. Cyc-domains are homologous to standard NRPS Condensation (C) domains. C-domains typically have a conserved HHxxxD motif at the active site; Cyc-domains have an alternative, conserved DxxxxD active site motif, mutation of the aspartate residues in this motif can abolish or diminish condensation activity. NRPS can use a large variety of acyl monomers (approximately 500 different possible monomer substrates as opposed to the 20 standard amino acids in ribosomal protein synthesis) to construct bioactive secondary metabolites of 2 to 18 units long (with various activities such as antibiotic, antifungal, antitumor and immunosuppression). There are various subtypes of C-domains such as the LCL-type which catalyzes peptide bond formation between two L-amino acids, the DCL-type which links an L-amino acid to the D-amino acid at the end of a growing peptide, starter C-domains which acylate the first amino acid with a beta-hydroxy carboxylic acid, and Cyc-domains. Typically, an NRPS module consists of an adenylation domain, a peptidyl carrier protein (PCP) domain (also known as thiolation (T) domain) and a C-domain. NRPS modules may also include specialized domains such as the terminal-module thioesterase (Te) domain that releases the product via hydrolysis or macrocyclization and any of various C-domain family members such as the epimerization (E) domain, the ester-bond forming C-domain, dual E/C (epimerization and condensation) domains, and the X-domain. |
| smart00825 | PKS_KS | 2.27e-130 | 29 | 447 | 1 | 296 | Beta-ketoacyl synthase. The structure of beta-ketoacyl synthase is similar to that of the thiolase family and also chalcone synthase. The active site of beta-ketoacyl synthase is located between the N and C-terminal domains. |
| smart00827 | PKS_AT | 2.58e-92 | 553 | 843 | 1 | 298 | Acyl transferase domain in polyketide synthase (PKS) enzymes. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| BAY30132.1 | 2.48e-158 | 29 | 892 | 1216 | 2097 |
| BAY90071.1 | 1.46e-156 | 29 | 896 | 1213 | 2098 |
| BAZ00088.1 | 1.30e-155 | 29 | 892 | 1214 | 2095 |
| BAZ75991.1 | 1.30e-155 | 29 | 892 | 1214 | 2095 |
| AFY93865.1 | 4.00e-136 | 8 | 890 | 939 | 1861 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 4MZ0_A | 1.35e-146 | 27 | 890 | 39 | 935 | ChainA, CurL [Moorena producens 3L],4MZ0_B Chain B, CurL [Moorena producens 3L] |
| 7VEE_A | 1.51e-132 | 27 | 894 | 21 | 915 | ChainA, Polyketide synthase [Streptomyces graminofaciens],7VEF_A Chain A, Polyketide synthase [Streptomyces graminofaciens] |
| 4OQJ_A | 6.56e-124 | 29 | 593 | 23 | 585 | Streptomcyesalbus JA3453 oxazolomycin ketosynthase domain OzmQ KS1 [Streptomyces albus] |
| 7S6B_A | 1.21e-118 | 27 | 892 | 58 | 933 | ChainA, Polyketide synthase [Streptomyces lasalocidi],7S6B_B Chain B, Polyketide synthase [Streptomyces lasalocidi] |
| 2HG4_A | 7.16e-118 | 13 | 890 | 24 | 898 | Structureof the ketosynthase-acyltransferase didomain of module 5 from DEBS. [Saccharopolyspora erythraea],2HG4_B Structure of the ketosynthase-acyltransferase didomain of module 5 from DEBS. [Saccharopolyspora erythraea],2HG4_C Structure of the ketosynthase-acyltransferase didomain of module 5 from DEBS. [Saccharopolyspora erythraea],2HG4_D Structure of the ketosynthase-acyltransferase didomain of module 5 from DEBS. [Saccharopolyspora erythraea],2HG4_E Structure of the ketosynthase-acyltransferase didomain of module 5 from DEBS. [Saccharopolyspora erythraea],2HG4_F Structure of the ketosynthase-acyltransferase didomain of module 5 from DEBS. [Saccharopolyspora erythraea] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P9WQE1 | 3.72e-151 | 29 | 892 | 8 | 896 | Phenolphthiocerol/phthiocerol polyketide synthase subunit E OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=ppsE PE=1 SV=1 |
| Q7TXL6 | 3.72e-151 | 29 | 892 | 8 | 896 | Phenolphthiocerol/phthiocerol polyketide synthase subunit E OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) OX=233413 GN=ppsE PE=1 SV=1 |
| P9WQE0 | 3.72e-151 | 29 | 892 | 8 | 896 | Phenolphthiocerol/phthiocerol polyketide synthase subunit E OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=ppsE PE=3 SV=1 |
| B2HIL7 | 7.92e-134 | 27 | 903 | 42 | 925 | Phenolphthiocerol synthesis polyketide synthase type I Pks15/1 OS=Mycobacterium marinum (strain ATCC BAA-535 / M) OX=216594 GN=pks15/1 PE=1 SV=1 |
| I6XD69 | 2.99e-133 | 27 | 1906 | 2057 | 4090 | Mycoketide-CoA synthase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pks12 PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.995402 | 0.004495 | 0.000109 | 0.000012 | 0.000005 | 0.000014 |