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CAZyme Information: MGYG000002518_03089
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Serratia surfactantfaciens | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Serratia; Serratia surfactantfaciens | |||||||||||
| CAZyme ID | MGYG000002518_03089 | |||||||||||
| CAZy Family | GT20 | |||||||||||
| CAZyme Description | Trehalose-6-phosphate synthase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 112916; End: 113605 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT20 | 22 | 227 | 1.9e-56 | 0.4357894736842105 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd03788 | GT20_TPS | 9.83e-51 | 25 | 224 | 37 | 240 | trehalose-6-phosphate synthase. Trehalose-6-Phosphate Synthase (TPS, EC 2.4.1.15) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. |
| COG0380 | OtsA | 1.78e-46 | 31 | 224 | 59 | 254 | Trehalose-6-phosphate synthase [Carbohydrate transport and metabolism]. |
| PRK10117 | PRK10117 | 1.08e-45 | 1 | 223 | 1 | 228 | trehalose-6-phosphate synthase; Provisional |
| pfam00982 | Glyco_transf_20 | 2.95e-42 | 28 | 224 | 43 | 244 | Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex,. |
| PRK14501 | PRK14501 | 5.11e-42 | 2 | 224 | 1 | 238 | putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AOF02025.1 | 1.92e-176 | 1 | 229 | 1 | 229 |
| QDI31566.1 | 1.11e-175 | 1 | 229 | 1 | 229 |
| ASM33920.1 | 1.11e-175 | 1 | 229 | 1 | 229 |
| QIR67185.1 | 1.11e-175 | 1 | 229 | 1 | 229 |
| QIO26085.1 | 1.58e-175 | 1 | 229 | 1 | 229 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5UOF_A | 8.70e-40 | 1 | 223 | 9 | 237 | Crystalstructure of alpha,alpha-trehalose 6-phosphate sythase from Burkholderia multivorans [Burkholderia multivorans ATCC 17616],5UOF_B Crystal structure of alpha,alpha-trehalose 6-phosphate sythase from Burkholderia multivorans [Burkholderia multivorans ATCC 17616] |
| 5TVG_A | 8.88e-38 | 3 | 223 | 11 | 237 | Crystalstructure of an alpha,alpha-trehalose-phosphate synthase (UDP-forming) from Burkholderia vietnamiensis [Burkholderia vietnamiensis G4],5TVG_B Crystal structure of an alpha,alpha-trehalose-phosphate synthase (UDP-forming) from Burkholderia vietnamiensis [Burkholderia vietnamiensis G4],5TVG_C Crystal structure of an alpha,alpha-trehalose-phosphate synthase (UDP-forming) from Burkholderia vietnamiensis [Burkholderia vietnamiensis G4],5TVG_D Crystal structure of an alpha,alpha-trehalose-phosphate synthase (UDP-forming) from Burkholderia vietnamiensis [Burkholderia vietnamiensis G4],5TVG_E Crystal structure of an alpha,alpha-trehalose-phosphate synthase (UDP-forming) from Burkholderia vietnamiensis [Burkholderia vietnamiensis G4],5TVG_F Crystal structure of an alpha,alpha-trehalose-phosphate synthase (UDP-forming) from Burkholderia vietnamiensis [Burkholderia vietnamiensis G4],5TVG_G Crystal structure of an alpha,alpha-trehalose-phosphate synthase (UDP-forming) from Burkholderia vietnamiensis [Burkholderia vietnamiensis G4],5TVG_H Crystal structure of an alpha,alpha-trehalose-phosphate synthase (UDP-forming) from Burkholderia vietnamiensis [Burkholderia vietnamiensis G4] |
| 5HXA_A | 9.13e-37 | 1 | 223 | 9 | 236 | Crystalstructure of an UDP-forming alpha, alpha-terhalose-phosphate synthase from Burkholderia xenovorans [Paraburkholderia xenovorans LB400] |
| 2WTX_A | 2.18e-36 | 1 | 228 | 1 | 233 | Insightinto the mechanism of enzymatic glycosyltransfer with retention through the synthesis and analysis of bisubstrate glycomimetics of trehalose-6-phosphate synthase [Escherichia coli K-12],2WTX_B Insight into the mechanism of enzymatic glycosyltransfer with retention through the synthesis and analysis of bisubstrate glycomimetics of trehalose-6-phosphate synthase [Escherichia coli K-12],2WTX_C Insight into the mechanism of enzymatic glycosyltransfer with retention through the synthesis and analysis of bisubstrate glycomimetics of trehalose-6-phosphate synthase [Escherichia coli K-12],2WTX_D Insight into the mechanism of enzymatic glycosyltransfer with retention through the synthesis and analysis of bisubstrate glycomimetics of trehalose-6-phosphate synthase [Escherichia coli K-12] |
| 1UQT_A | 2.42e-36 | 1 | 228 | 1 | 233 | Trehalose-6-phosphatefrom E. coli bound with UDP-2-fluoro glucose. [Escherichia coli],1UQT_B Trehalose-6-phosphate from E. coli bound with UDP-2-fluoro glucose. [Escherichia coli],1UQU_A Trehalose-6-phosphate from E. coli bound with UDP-glucose. [Escherichia coli],1UQU_B Trehalose-6-phosphate from E. coli bound with UDP-glucose. [Escherichia coli] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| A6TB47 | 1.59e-39 | 1 | 228 | 1 | 233 | Trehalose-6-phosphate synthase OS=Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578) OX=272620 GN=otsA PE=3 SV=1 |
| A7MEE9 | 2.22e-39 | 1 | 228 | 1 | 233 | Trehalose-6-phosphate synthase OS=Cronobacter sakazakii (strain ATCC BAA-894) OX=290339 GN=otsA PE=3 SV=1 |
| A4WBR1 | 8.49e-38 | 1 | 228 | 1 | 233 | Trehalose-6-phosphate synthase OS=Enterobacter sp. (strain 638) OX=399742 GN=otsA PE=3 SV=1 |
| Q2NTK9 | 8.06e-36 | 1 | 228 | 1 | 233 | Trehalose-6-phosphate synthase OS=Sodalis glossinidius (strain morsitans) OX=343509 GN=otsA PE=3 SV=1 |
| Q1RAP1 | 8.61e-36 | 1 | 228 | 1 | 233 | Trehalose-6-phosphate synthase OS=Escherichia coli (strain UTI89 / UPEC) OX=364106 GN=otsA PE=3 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000032 | 0.000024 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |