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CAZyme Information: MGYG000002536_01852
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Plesiomonas shigelloides | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Plesiomonas; Plesiomonas shigelloides | |||||||||||
| CAZyme ID | MGYG000002536_01852 | |||||||||||
| CAZy Family | GT2 | |||||||||||
| CAZyme Description | Acetyl-coenzyme A synthetase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 8034; End: 9995 Strand: + | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG0365 | Acs | 0.0 | 68 | 631 | 1 | 528 | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase [Lipid transport and metabolism]. |
| PRK00174 | PRK00174 | 0.0 | 6 | 648 | 1 | 636 | acetyl-CoA synthetase; Provisional |
| cd05968 | AACS_like | 0.0 | 22 | 635 | 7 | 610 | Uncharacterized acyl-CoA synthetase subfamily similar to Acetoacetyl-CoA synthetase. This uncharacterized acyl-CoA synthetase family (EC 6.2.1.16, or acetoacetate#CoA ligase or acetoacetate:CoA ligase (AMP-forming)) is highly homologous to acetoacetyl-CoA synthetase. However, the proteins in this family exist in only bacteria and archaea. AACS is a cytosolic ligase that specifically activates acetoacetate to its coenzyme A ester by a two-step reaction. Acetoacetate first reacts with ATP to form an acyl-adenylate intermediate, which then reacts with CoA to produce an acyl-CoA ester. This is the first step of the mevalonate pathway of isoprenoid biosynthesis via isopentenyl diphosphate. Isoprenoids are a large class of compounds found in all living organisms. |
| PLN02654 | PLN02654 | 0.0 | 12 | 643 | 19 | 662 | acetate-CoA ligase |
| TIGR02188 | Ac_CoA_lig_AcsA | 0.0 | 18 | 644 | 1 | 626 | acetate--CoA ligase. This model describes acetate-CoA ligase (EC 6.2.1.1), also called acetyl-CoA synthetase and acetyl-activating enzyme. It catalyzes the reaction ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA and belongs to the family of AMP-binding enzymes described by pfam00501. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| CAE6201330.1 | 1.09e-246 | 12 | 642 | 569 | 1210 |
| CAE6201338.1 | 1.49e-246 | 12 | 642 | 580 | 1221 |
| AFZ04852.1 | 2.28e-21 | 67 | 615 | 571 | 1074 |
| CAE6256584.1 | 5.21e-19 | 253 | 618 | 1706 | 2058 |
| BAY90071.1 | 5.42e-19 | 81 | 615 | 579 | 1078 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 2P2Q_A | 0.0 | 1 | 648 | 1 | 648 | ChainA, Acetyl-coenzyme A synthetase [Salmonella enterica subsp. enterica serovar Typhimurium],2P2Q_B Chain B, Acetyl-coenzyme A synthetase [Salmonella enterica subsp. enterica serovar Typhimurium] |
| 2P2J_A | 0.0 | 1 | 648 | 1 | 648 | ChainA, Acetyl-coenzyme A synthetase [Salmonella enterica subsp. enterica serovar Typhimurium],2P2J_B Chain B, Acetyl-coenzyme A synthetase [Salmonella enterica subsp. enterica serovar Typhimurium] |
| 2P2M_A | 0.0 | 1 | 648 | 1 | 648 | ChainA, Acetyl-coenzyme A synthetase [Salmonella enterica subsp. enterica serovar Typhimurium],2P2M_B Chain B, Acetyl-coenzyme A synthetase [Salmonella enterica subsp. enterica serovar Typhimurium] |
| 1PG3_A | 0.0 | 1 | 648 | 1 | 648 | ChainA, acetyl-CoA synthetase [Salmonella enterica],1PG3_B Chain B, acetyl-CoA synthetase [Salmonella enterica],1PG4_A Chain A, acetyl-CoA synthetase [Salmonella enterica],1PG4_B Chain B, acetyl-CoA synthetase [Salmonella enterica] |
| 5JRH_A | 0.0 | 1 | 648 | 1 | 648 | Crystalstructure of Salmonella enterica acetyl-CoA synthetase (Acs) in complex with cAMP and Coenzyme A [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],5JRH_B Crystal structure of Salmonella enterica acetyl-CoA synthetase (Acs) in complex with cAMP and Coenzyme A [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q7MBA6 | 0.0 | 1 | 648 | 1 | 648 | Acetyl-coenzyme A synthetase OS=Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01) OX=243265 GN=acs PE=3 SV=1 |
| Q8D1G8 | 0.0 | 1 | 648 | 1 | 648 | Acetyl-coenzyme A synthetase OS=Yersinia pestis OX=632 GN=acs PE=3 SV=2 |
| Q87KU7 | 0.0 | 1 | 648 | 1 | 649 | Acetyl-coenzyme A synthetase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) OX=223926 GN=acsA PE=3 SV=1 |
| Q7MGU3 | 0.0 | 1 | 648 | 1 | 649 | Acetyl-coenzyme A synthetase OS=Vibrio vulnificus (strain YJ016) OX=196600 GN=acsA PE=3 SV=2 |
| Q8DCZ9 | 0.0 | 1 | 648 | 1 | 649 | Acetyl-coenzyme A synthetase OS=Vibrio vulnificus (strain CMCP6) OX=216895 GN=acsA PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000025 | 0.000019 | 0.000004 | 0.000000 | 0.000000 | 0.000000 |