logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000002543_00916

You are here: Home > Sequence: MGYG000002543_00916

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Campylobacter_B ureolyticus
Lineage Bacteria; Campylobacterota; Campylobacteria; Campylobacterales; Campylobacteraceae; Campylobacter_B; Campylobacter_B ureolyticus
CAZyme ID MGYG000002543_00916
CAZy Family GT66
CAZyme Description Undecaprenyl-diphosphooligosaccharide--protein glycotransferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
694 MGYG000002543_9|CGC2 79221.2 8.5005
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002543 1665696 Isolate Ireland Europe
Gene Location Start: 180031;  End: 182115  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.99.19

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT66 15 578 3.4e-93 0.9018759018759018

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam02516 STT3 2.15e-44 26 467 21 477
Oligosaccharyl transferase STT3 subunit. This family consists of the oligosaccharyl transferase STT3 subunit and related proteins. The STT3 subunit is part of the oligosaccharyl transferase (OTase) complex of proteins and is required for its activity. In eukaryotes, OTase transfers a lipid-linked core-oligosaccharide to selected asparagine residues in the ER. In the archaea STT3 occurs alone, rather than in an OTase complex, and is required for N-glycosylation of asparagines.
COG1287 Stt3 1.52e-36 12 627 22 682
Asparagine N-glycosylation enzyme, membrane subunit Stt3 [Posttranslational modification, protein turnover, chaperones].
pfam18527 STT3_PglB_C 2.07e-22 577 654 1 79
STT3/PglB C-terminal beta-barrel domain. Asparagine-linked glycosylation is a post-translational modification of proteins containing the conserved sequence motif Asn-X-Ser/Thr. The attachment of oligosaccharides is implicated in diverse processes such as protein folding and quality control, organism development or host-pathogen interactions. The reaction is catalysed by oligosaccharyltransferase (OST), a membrane protein complex located in the endoplasmic reticulum. The central, catalytic enzyme of OST is the STT3 subunit, which has homologues in bacteria and archaea. Structural analysis of a bacterial OST, undecaprenyl-diphosphooligosaccharide protein glycotransferase EC:2.4.99.19 (PglB) protein, revealed two domains: a transmembrane domain and a periplasmic domain. This entry represents the C-terminal periplasmic beta-barrel domain.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QIX86759.1 0.0 1 694 1 694
QQY34902.1 0.0 1 694 1 694
QKF84933.1 0.0 1 694 1 694
AKT91207.1 0.0 1 694 1 694
QKF71851.1 8.62e-274 1 693 1 698

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3RCE_A 1.85e-189 7 693 11 711
Bacterialoligosaccharyltransferase PglB [Campylobacter lari]
5OGL_A 9.59e-184 7 693 11 711
Structureof bacterial oligosaccharyltransferase PglB in complex with an acceptor peptide and an lipid-linked oligosaccharide analog [Campylobacter lari RM2100]
6GXC_A 1.36e-183 7 693 11 711
Bacterialoligosaccharyltransferase PglB in complex with an inhibitory peptide and a reactive lipid-linked oligosaccharide analog [Campylobacter lari RM2100]
3AAG_A 1.19e-59 419 694 7 291
Crystalstructure of C. jejuni pglb C-terminal domain [Campylobacter jejuni RM1221],3AAG_B Crystal structure of C. jejuni pglb C-terminal domain [Campylobacter jejuni RM1221]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q5HTX9 1.22e-203 14 694 16 713
Undecaprenyl-diphosphooligosaccharide--protein glycotransferase OS=Campylobacter jejuni (strain RM1221) OX=195099 GN=pglB PE=1 SV=1
Q0P9C8 1.73e-203 14 694 16 713
Undecaprenyl-diphosphooligosaccharide--protein glycotransferase OS=Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) OX=192222 GN=pglB PE=1 SV=1
B9KDD4 8.62e-190 7 693 11 711
Undecaprenyl-diphosphooligosaccharide--protein glycotransferase OS=Campylobacter lari (strain RM2100 / D67 / ATCC BAA-1060) OX=306263 GN=pglB PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.998819 0.000677 0.000142 0.000004 0.000003 0.000376

TMHMM  Annotations      download full data without filtering help

start end
12 34
98 117
145 167
187 209
222 244
259 281
325 347
362 384
396 414