CAZyme Information: MGYG000002554_00691

Basic Information

• Species: Streptococcus oralis_W
• Lineage: Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus oralis_W
• CAZyme ID: MGYG000002554_00691
• CAZy Family: GH2
• CAZyme Description: Beta-galactosidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1516		168582.3	6.1565

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002554	1500206	MAG	China	Asia

• Gene Location: Start: 75; End: 4625 Strand: +

Full Sequence      

MKEEEPVAPKEEKTSLKPEETAPKVESQASSQEKPVKEELKAATNEEVNQMIEDRKVNFN
QNWHFKLNANPKEAVKSDADVSTWQKLDLPHDWSIFNDFDHQSPAQNEGGQLNGGEAWYR
KTFKLDEKDLKKNVRVTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENV
IAVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEQQQHGKVETHVAS
KIVNTDDKDHELVAEYQIVERGGQAVTGLVRTASRTLKAHESTSLDAILEVEQPKLWTVL
NDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLHHDHGA
LGAEENYKAEYRRLKQMKEMGVNAIRTTHNPASPQTLQIAAELGLLVQEEAFDTWYGGKK
PYDYGRFFEKDATHPEARKGEKWSDYDLRTMVERDKNNPAVFMWSIGNEIGEANGNAHSL
ATVKRLVKVIKDVDTTRYVTMGADKFRFGDGSGDHEKIANELDAVGFNYSEDNYKKLRAK
HPNWLIYGSETSSATRTRGSYYRPEQELVHSNQAYRNYEQSDYGNDRVGWGKTATASWTF
DRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAGIPKNDFYLYQSQWVS
AKKKPMVHLLPHWNWENKELADKVADSEGKIPVRAYSNAASVELFLNGQSLGVKKFNKKQ
TSDGRTYQEGANAKELYLEWKVAYQPGTLEAVARDEAGKEIARDKITTAGQPAGVRLVKE
EHAIAADGKDLTYIYYEIVDSEGNVVPTANNLVRFQLHGQGQLIGVDNGEQASRERYKAQ
PDGSWIRRAFNGKGVAIVKSTEQAGKFTLTAHSDLLKSSQVTVFTGKKEDQEKTVLGTEV
PKVRTVIEKEPKMPKTVGFIYSDGSREKRPVTWSSVDVSQAGVVTVKGMADGREVEARVE
ILAIANELPTVKRVAPGTDLSAVDKYVSIAVTDGSVQEYEVDNWEIAPEDQAKLSVAGSR
IQMTGQLGGETIHATLVVEEGEAAAPVVPTVTVGDETVTGLTTQKPMQYRTLAYGAKLPK
VTASAENAAVTVVQASAANGMRASIFVQPNDGGPLQMYAIQFLEEAPKIDHLSLQVEKAD
ALKEDQTVKLSVLAHYQDGTQAVLPADKVNFSTSGEGEVAVRKGMLELHKPGTVALKAEY
EGATGQINLTIRANTEKKVAQAIRPVNVVTDLHQEPSLPATVTVEYDKGFPKAHKVTWQT
IPKEKLDHYQIFEVLGKVEGLDLDARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYD
SNGHVSSAKVTWDTIRPDQYAKEGVFTVNGRLEGTQLITKLHVRVSAQTEKGANISDQWT
GSELPLAFASDSNPTDPVSNVNDKLISFNDRPANRWTNWNRTNPEASVGVLFGDSGILSK
RSVDNLSVGFHEDHGVGVPKSYVIEYYVGKTVPTAPKNPSFVGEENHAFNDPANWKEVSN
LKAPAQLSWRNESFQF

Enzyme Prediction     

No EC number prediction in MGYG000002554_00691.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	32	795	2.2e-114	0.7992021276595744
CBM71	1373	1511	4.5e-61	0.7024390243902439

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG3250	LacZ	0.0	37	871	9	803	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10150	PRK10150	1.02e-34	63	500	19	446	beta-D-glucuronidase; Provisional
pfam18565	Glyco_hydro2_C5	7.59e-34	776	882	2	103	Glycoside hydrolase family 2 C-terminal domain 5. Domain 5 is found in dimeric beta-D-galactosidase from Paracoccus sp. 32d, which contributes to stabilization of the functional dimer. It is suggested that the location of this domain 5, may be one of the factors responsible for the creation of a functional dimer and cold-adaptation of this enzyme.
PRK10340	ebgA	7.32e-32	58	499	43	472	cryptic beta-D-galactosidase subunit alpha; Reviewed
PRK09525	lacZ	3.29e-27	54	499	50	485	beta-galactosidase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CBZ00361.1	0.0	28	1507	123	1602
QLL97214.1	0.0	1	1507	96	1602
APU52328.1	0.0	1	1507	96	1602
QLL99025.1	0.0	15	1507	110	1602
QXW62013.1	0.0	1	1507	96	1602

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4CU6_A	0.0	42	889	1	848	Unravellingthe multiple functions of the architecturally intricate Streptococcus pneumoniae beta-galactosidase, BgaA [Streptococcus pneumoniae TIGR4],4CU7_A Unravelling the multiple functions of the architecturally intricate Streptococcus pneumoniae beta-galactosidase, BgaA [Streptococcus pneumoniae TIGR4],4CU8_A Unravelling the multiple functions of the architecturally intricate Streptococcus pneumoniae beta-galactosidase, BgaA [Streptococcus pneumoniae TIGR4]
4CUC_A	0.0	42	889	1	848	Unravellingthe multiple functions of the architecturally intricate Streptococcus pneumoniae beta-galactosidase, BgaA. [Streptococcus pneumoniae TIGR4]
4YPJ_A	6.63e-267	54	885	7	807	ChainA, Beta galactosidase [Niallia circulans],4YPJ_B Chain B, Beta galactosidase [Niallia circulans]
7CWD_A	1.26e-258	55	891	2	807	ChainA, beta-glalactosidase [Niallia circulans],7CWI_A Chain A, beta-galactosidase [Niallia circulans]
7NIT_A	3.11e-195	53	962	29	959	ChainA, Beta-galactosidase [Bifidobacterium bifidum],7NIT_B Chain B, Beta-galactosidase [Bifidobacterium bifidum],7NIT_C Chain C, Beta-galactosidase [Bifidobacterium bifidum],7NIT_D Chain D, Beta-galactosidase [Bifidobacterium bifidum],7NIT_E Chain E, Beta-galactosidase [Bifidobacterium bifidum],7NIT_F Chain F, Beta-galactosidase [Bifidobacterium bifidum]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
A7LXS9	1.35e-174	59	883	47	846	Beta-galactosidase BoGH2A OS=Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC 11153) OX=411476 GN=BACOVA_02645 PE=1 SV=1
T2KM09	1.10e-104	58	829	50	768	Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22050 PE=2 SV=2
T2KPJ7	4.29e-54	56	859	53	799	Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_21970 PE=2 SV=1
T2KN75	2.47e-49	58	911	30	820	Beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22060 PE=1 SV=1
P77989	8.05e-48	57	885	6	738	Beta-galactosidase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=lacZ PE=3 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000033	0.000009	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002554_00691.