CAZyme Information: MGYG000002560_03898

Basic Information

• Species: Phocaeicola sp902388365
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Phocaeicola; Phocaeicola sp902388365
• CAZyme ID: MGYG000002560_03898
• CAZy Family: GH115
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
831		95585.51	6.8195

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002560	5390440	MAG	China	Asia

• Gene Location: Start: 39048; End: 41543 Strand: -

Full Sequence      

MRTKTIWMLCTLMSWLLLQPLSAVERFVSNDGTHFAWIQNGKAYPILVDQQEDKGVLRSI
ANLQTDAEKVTGVKPEIRNTISGNKMLIIGSIDHSDWIKQLLSSGKLTASDLQGKREKYI
IQTIKNPLDGVEEAVVIAGSDKRGTIYGIYELSSQMGVSPWYYWADVPVEKQNKISIKTG
KYTDGEPAVRFRGIFLNDEAPALSGWTRETFGGFNSKFYEKVFELILRLKGNFMWPAMWG
NAFYDDDPANGPLANEMGIVMGTSHHEPMGLAQQDWKRRGTGAWNYTTNGAVLRDFWQTG
MERCKDWEAVITVGMRGDGDEPMSEDANISLLQNIVKDQRKIISKVTGKKPSETPQVWAL
YKEVQDYYDKGMRVPDDVTLLLCDDNWGNVRKLPDLKAKPRKGGYGMYYHFDYVGGPRNS
KWINITQIQRTWEQMNLTYEHGVRQLWVVNVGDLKPMEYPITFFLDFAWDPSRFNENNLF
SHTERFCEQQFGAKYAKEAARLIDTYTKYNRRVTPELLSDKTYSLENYNEWQRVKDDYVA
LSLDALRLYYLMPDNYRDAFDQLVLFPIQACSNLYEMYYALAMNRSLAAKHDTKANQWGT
KVRDCFERDSVLTYHYNKVMSKGKWNHMMDQTHIGYQSWFDPKYNVMPEVSMIPESRIAP
APYLFKEKDGYVSMEAEHYTRSSNGATAQWITIPNLGRTLSAVTTSPCTSIPDKDMYLEY
DFETDRNGEATVDVRFSATLNFNENKGLRYAISLDGEPEQIININGHYKGELGKWQAEHI
ITTQTKHRVNQKEKHTLRIRPLDPALVIQKIMINFGGLKPSFLGAPESLEN

Enzyme Prediction     

EC	3.2.1.131

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH115	34	811	3e-286	0.9956958393113343

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam15979	Glyco_hydro_115	0.0	185	517	1	334	Glycosyl hydrolase family 115. Glyco_hydro_115 is a family of glycoside hydrolases likely to have the activity of xylan a-1,2-glucuronidase, EC:3.2.1.131, or a-(4-O-methyl)-glucuronidase EC:3.2.1.-.
pfam17829	GH115_C	1.05e-58	665	827	2	172	Gylcosyl hydrolase family 115 C-terminal domain. This domain is found at the C-terminus of glycosyl hydrolase family 115 proteins. This domain has a beta-sandwich fold.
pfam03648	Glyco_hydro_67N	8.19e-05	15	152	2	120	Glycosyl hydrolase family 67 N-terminus. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the N-terminal region of alpha-glucuronidase. The N-terminal domain forms a two-layer sandwich, each layer being formed by a beta sheet of five strands. A further two helices form part of the interface with the central, catalytic, module (pfam07488).

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ALJ61511.1	0.0	1	828	1	828
QUT92919.1	0.0	1	828	1	828
EDV05080.1	0.0	1	829	17	845
QDO71564.1	0.0	16	829	1	814
QIU93956.1	0.0	33	830	31	822

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4C90_A	3.70e-299	23	828	30	849	Evidencethat GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C90_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_A Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus]
7PUG_A	5.58e-277	35	828	17	834	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
7PXQ_A	4.01e-274	35	828	16	833	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
4ZMH_A	3.72e-220	46	828	25	933	Crystalstructure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40],4ZMH_B Crystal structure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40]
6NPS_A	7.52e-137	42	653	17	658	Crystalstructure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112],6NPS_B Crystal structure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000398	0.998909	0.000207	0.000150	0.000142	0.000148

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002560_03898.