CAZyme Information: MGYG000002592_00551

Basic Information

• Species: Alistipes sp902388705
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae; Alistipes; Alistipes sp902388705
• CAZyme ID: MGYG000002592_00551
• CAZy Family: GH127
• CAZyme Description: Non-reducing end beta-L-arabinofuranosidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
688	MGYG000002592_4|CGC3	75972.49	5.7579

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002592	2965227	MAG	China	Asia

• Gene Location: Start: 143380; End: 145446 Strand: -

Full Sequence      

MKPAKTLLLALPLLAAGCSPDNGTAKIRPLEAGTVTVEDTFWSPRFEKWEHVTVGDMLDK
FEGNDPAHFACGVDAFENFDLVASGARDIGRHAGPPWYDGLVYETIRGIADLLAQRPDSA
LKARVDGYIARIEAAQQSDSDGFLGTHTQLTEDGHRWGANGGLLRMQHDVYNAGMLVEAG
VHYYKATGDARLLRIATRFADYMVRIMGPSPKKNIVPAHSGPEEALIKLYRLYRDEPQLR
EQTGAQSAAGDYLALAEFWIGNRGVHCGQPLWGTWGNDSAERWIHKNLYTAQFGPDARPT
WGDYAQDSIRVFEQPAIVGHAVRATLLATGIAAAACENGDERYIATAKRWWDDMAGRKLF
LTGGVGAVHFDEKFGHDYFLPTDAYLETCAAVGVGFFSQSMNSLTGDAKYMDEFERALYN
NVLAGVSASGDRYTYQNPLNTDRSERWEWHPCPCCPPMFLKIVSATPGFIYAEDGKSLYV
NLFIGSRTDIALGGTRINVRQQTGYPADGQVDLTLTPDKASRFAVRIRIPGWARGEENPF
GLYVSESNGKPQLSVNGTPVEIRLERGYAVIERRWQPDDRISLQLPVAPRVIRAHEQARE
LDGKVALAAGPFVYCIEQADNADYDRLELDTAGGMRLEYRSDLMGGTPVITGTAVTEEGV
QTRFTAIPYHAFGNRGNGGYRVWLPALR

Enzyme Prediction     

No EC number prediction in MGYG000002592_00551.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH127	35	615	5.3e-166	0.9980916030534351

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam07944	Glyco_hydro_127	6.53e-155	35	615	2	503	Beta-L-arabinofuranosidase, GH127. One member of this family, from Bidobacterium longicum, UniProtKB:E8MGH8, has been characterized as an unusual beta-L-arabinofuranosidase enzyme, EC:3.2.1.185. It rleases l-arabinose from the l-arabinofuranose (Araf)-beta1,2-Araf disaccharide and also transglycosylates 1-alkanols with retention of the anomeric configuration. Terminal beta-l-arabinofuranosyl residues have been found in arabinogalactan proteins from a mumber of different plantt species. beta-l-Arabinofuranosyl linkages with 1-4 arabinofuranosides are also found in the sugar chains of extensin and solanaceous lectins, hydroxyproline (Hyp)2-rich glycoproteins that are widely observed in plant cell wall fractions. The critical residue for catalytic activity is Glu-338, in a ET/SCAS sequence context.
COG3533	COG3533	1.03e-123	34	686	11	587	Uncharacterized conserved protein, DUF1680 family [Function unknown].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
BBL00048.1	0.0	1	685	1	685
BBL08129.1	0.0	1	685	1	685
BBL10920.1	0.0	1	685	1	685
QCQ43239.1	8.95e-299	1	686	1	687
BAD47118.1	8.95e-299	1	686	1	687

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4QJY_A	1.09e-108	32	684	13	645	Crystalstructure of native Ara127N, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QJY_B Crystal structure of native Ara127N, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus]
6EX6_A	1.17e-107	22	685	2	624	TheGH127, Beta-arabinofuranosidase, BT3674 [Bacteroides thetaiotaomicron VPI-5482],6EX6_B The GH127, Beta-arabinofuranosidase, BT3674 [Bacteroides thetaiotaomicron VPI-5482]
4QK0_A	8.95e-107	32	684	13	645	Crystalstructure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_B Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_C Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_D Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus]
3WRE_A	1.56e-77	35	683	3	655	Thecrystal structure of native HypBA1 from Bifidobacterium longum JCM 1217 [Bifidobacterium longum subsp. longum JCM 1217],3WRG_A The complex structure of HypBA1 with L-arabinose [Bifidobacterium longum subsp. longum JCM 1217]
3WKW_A	1.97e-77	35	683	3	655	Crystalstructure of GH127 beta-L-arabinofuranosidase HypBA1 from Bifidobacterium longum ligand free form [Bifidobacterium longum subsp. longum JCM 1217],3WKX_A Crystal structure of GH127 beta-L-arabinofuranosidase HypBA1 from Bifidobacterium longum arabinose complex form [Bifidobacterium longum subsp. longum JCM 1217],7BZL_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7DIF_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7EXV_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7EXW_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
E8MGH8	8.56e-77	35	683	3	655	Non-reducing end beta-L-arabinofuranosidase OS=Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b) OX=565042 GN=hypBA1 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as LIPO

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000000	0.000003	1.000057	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002592_00551.