CAZyme Information: MGYG000002596_01410

Basic Information

• Species: Mediterraneibacter sp900555215
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter; Mediterraneibacter sp900555215
• CAZyme ID: MGYG000002596_01410
• CAZy Family: GT2
• CAZyme Description: Cellulose synthase catalytic subunit [UDP-forming]

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
647	MGYG000002596_39|CGC1	74349.82	6.9371

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002596	2662706	MAG	China	Asia

• Gene Location: Start: 4984; End: 6927 Strand: -

Full Sequence      

MEPENKRNCIFMLAICFSSIYLIWRVFGTIPWTDGAFQAAAGILLVLAEIITTLGMFELM
ISRMKAKKVIRDLPDVPEEQYPDVDVLIATHNEPAELLYKTVNACTFLEYPDKGKVHIYL
CDDGGRREAEELAQRLGVGYLGFSDNRHAKSGNYNNALSRTSSPLIATFDADMIPRREFL
VKTVPYFLDPEVKMGLVQTPQSFYNQDLFQFNLFSEKDIPNEQDFFSREINVMRNASNSA
AYTGSNTVILRRALEEIGGFPYGTVTEDFETSLRLQKAGYVTYASTEVLAAGLSTTTVES
MIRQRVRWARGVIQSIQNTNAIFTKDLPAAGRLAYLNAYLYWWSFLCRMIFILSPILFAL
FDFRLVECGFWELLAFWLPSHLLYSISVRYLSTNVRNMRWSQIIDTILAPYLILPVFFES
IGIHQQKFKVTDKKKRRGRTASFRFLIPHGILLVLTLVSLIKFSYGKYGMALVYSSVILF
WLCYNLIGLVYAVFFMLGREVKRKNERIRAEEPVRIRTRQTDMEGMTLDVSEDGIAFRIS
GGEAVAEEEEEHCPVLKGGEQFCISVLTERYTADLDAELAYSKQDEKGRIYAASVMPLSE
ADKRNWLQIIHDREHSLPREIDPWRTLYDDVCQNIFLRRKGEGVWKR

Enzyme Prediction     

No EC number prediction in MGYG000002596_01410.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	83	311	1.9e-28	0.991304347826087

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd06421	CESA_CelA_like	4.03e-90	82	314	1	232	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose. Family of proteins related to Agrobacterium tumefaciens CelA and Gluconacetobacter xylinus BscA. These proteins are involved in the elongation of the glucan chain of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues. They are putative catalytic subunit of cellulose synthase, which is a glycosyltransferase using UDP-glucose as the substrate. The catalytic subunit is an integral membrane protein with 6 transmembrane segments and it is postulated that the protein is anchored in the membrane at the N-terminal end.
PRK11498	bcsA	6.20e-83	13	542	192	723	cellulose synthase catalytic subunit; Provisional
COG1215	BcsA	1.98e-51	43	461	17	406	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility].
cd06435	CESA_NdvC_like	3.20e-34	91	314	7	230	NdvC_like proteins in this family are putative bacterial beta-(1,6)-glucosyltransferase. NdvC_like proteins in this family are putative bacterial beta-(1,6)-glucosyltransferase. Bradyrhizobium japonicum synthesizes periplasmic cyclic beta-(1,3),beta-(1,6)-D-glucans during growth under hypoosmotic conditions. Two genes (ndvB, ndvC) are involved in the beta-(1, 3), beta-(1,6)-glucan synthesis. The ndvC mutant strain resulted in synthesis of altered cyclic beta-glucans composed almost entirely of beta-(1, 3)-glycosyl linkages. The periplasmic cyclic beta-(1,3),beta-(1,6)-D-glucans function for osmoregulation. The ndvC mutation also affects the ability of the bacteria to establish a successful symbiotic interaction with host plant. Thus, the beta-glucans may function as suppressors of a host defense response.
pfam13641	Glyco_tranf_2_3	6.02e-24	82	311	2	230	Glycosyltransferase like family 2. Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
SMF90406.1	1.42e-268	1	635	1	647
QNK55597.1	4.05e-262	1	635	1	654
QLG37677.1	1.33e-261	1	635	1	647
QOS81892.1	1.88e-261	1	635	1	647
QZN77042.1	6.17e-260	1	635	1	647

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7LBY_A	4.98e-70	1	561	193	754	ChainA, Cellulose synthase catalytic subunit [UDP-forming] [Escherichia coli K-12]
5EJ1_A	8.52e-61	21	539	68	607	ChainA, Putative cellulose synthase [Cereibacter sphaeroides 2.4.1]
4HG6_A	2.23e-60	21	539	80	619	ChainA, Cellulose Synthase Subunit A [Cereibacter sphaeroides]
4P00_A	2.26e-60	21	539	81	620	ChainA, Cellulose Synthase A subunit [Cereibacter sphaeroides 2.4.1],4P02_A Chain A, Cellulose Synthase subunit A [Cereibacter sphaeroides 2.4.1],5EIY_A Chain A, Putative cellulose synthase [Cereibacter sphaeroides 2.4.1],5EJZ_A Chain A, Putative cellulose synthase [Cereibacter sphaeroides 2.4.1]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q93IN2	9.49e-71	1	574	193	768	Cellulose synthase catalytic subunit [UDP-forming] OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=bcsA PE=3 SV=1
Q8Z291	1.31e-70	1	574	193	768	Cellulose synthase catalytic subunit [UDP-forming] OS=Salmonella typhi OX=90370 GN=bcsA PE=3 SV=1
Q8X5L7	8.75e-70	1	561	193	754	Cellulose synthase catalytic subunit [UDP-forming] OS=Escherichia coli O157:H7 OX=83334 GN=bcsA PE=3 SV=2
P37653	2.29e-69	1	561	193	754	Cellulose synthase catalytic subunit [UDP-forming] OS=Escherichia coli (strain K12) OX=83333 GN=bcsA PE=1 SV=3
P58931	1.96e-65	12	593	90	662	Cellulose synthase catalytic subunit [UDP-forming] OS=Pseudomonas fluorescens (strain SBW25) OX=216595 GN=bcsA PE=3 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000016	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

start	end
7	29
39	61
339	361
400	422
442	461
476	498