CAZyme Information: MGYG000002602_01424

Basic Information

• Species: CAG-274 sp900545305
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; CAG-274; CAG-274; CAG-274 sp900545305
• CAZyme ID: MGYG000002602_01424
• CAZy Family: PL9
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1303	MGYG000002602_7|CGC2	141349.93	4.7658

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002602	2192997	MAG	China	Asia

• Gene Location: Start: 58774; End: 62685 Strand: -

Full Sequence      

MKKRLVCFGLALAFSLSSFSAISFAEGSWKKGWTGKADAAAYTVNANGSTVTMSNDNVNN
GKFTDGEDSIVYYANELKADENFELKATVNIDSYNTAKDGSNPQQGSVGIGVLDSLYNKT
DDKTYDDGVFLGSYASQKDSPMAIHSLVRANSSKKTVGDALSDTFANTGENLGTFDLSIK
KVGNAYTLTCGDKSTTVEMTAMEDEIYPCLYIARNAKATFTNVSLKTETRKATSLTLKGK
CKTAYSYGEKLDLSGLTGTVTYDDGTKEDVTGFLASGYDATKTGKQTITLSYGDAKANID
VSVANVALTDVKIGFTPVKTDYSLNGPFSSTGISVEAVYSDGTTKKLDSDQYTFSLNGKT
IKDGDAVTGVGHQIVKVNVKPQKGINTTAVGSYNIYINKNAYSSLEAKGKGFNTDYYLND
QFDTNTIEVTASYTNDSGKVVSEIVPAGSYTLTGFDSKTAGEKEVKISAGGLEVSNTVTV
KEKQVTGIELTKYPKTTYNVGESFDKEDMAVVVKYDNGDEDELTDYTVNTDKFDTSKVGK
TSVTVSSKEGSVELPCTVVEAKDAKWRKVVFGQSSNYDKQDEGISGVTADDYGTANGKIN
VRSWNGSGKITQDHDGISYYYTTVDGNEDFRVTADIKVNKYLEHDNNDTKRSGQEAFGIM
ARDVIPLTGEDGKIVTDENSAKKDSEGISQPLDNGAVFASNMVICGGYSGTGYPADKSIS
NYDNIINMNRINLIVREGVTATDGGGKRIGPYAINSEFPKEGNTYRVTLERMNGGLYAKC
YDYQTGKTQSTVYNDDSFLTVQSDKVYVGFFTSRWADIDVSNVEFRTSDRSTDQKVAEKE
EEPATAGLSFKTKGYSTSENYGFDLAASDSKGKVTIKVNDAVVAQNVDMADTQHFTAKLK
NNTANKIVAVYTPDKSLNLSSYEPIVVRKTVYCKETPANATTLYVSPQGSFNGDGTKENP
FDIDTAIGLCKAGQTVQLAGGVYNRTSRIDISIGDDGTAEKPKTIRADENDRAIIDLGAT
CAGFYTGGNYWVFENMDVRNSGNNLKAFNLGGSHCVVRNCRFYDNRDTGFQISRIDDNQT
REFWPGYNLVENCESFNNCDPAMINADGFGTKLTSGDGNVYRNCKSHHNLDDGWDCYTKV
NTGAIGAVTLENCQAYKMGLRLNEDGTETPYGAGGHNGFKMGGENIAVNHVLKNCVAYDN
LACGVTTNFNPSLTLIDVKAYNNAESNFNFFTDKADQYNYTVTGAVSYNGGAADRIPTEN
YNKEYKNNSQTPLISESNYWELALGKSVNKSGREANESMLKMK

Enzyme Prediction     

No EC number prediction in MGYG000002602_01424.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
PL9	939	1294	2.2e-103	0.9386666666666666

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam07523	Big_3	2.56e-07	242	303	4	67	Bacterial Ig-like domain (group 3). This family consists of bacterial domains with an Ig-like fold. Members of this family are found in a variety of bacterial surface proteins.
pfam07523	Big_3	4.98e-07	492	558	1	67	Bacterial Ig-like domain (group 3). This family consists of bacterial domains with an Ig-like fold. Members of this family are found in a variety of bacterial surface proteins.
cd14251	PL-6	1.60e-06	965	1093	9	133	Polysaccharide Lyase Family 6. Polysaccharide Lyase Family 6 is a family of beta-helical polysaccharide lyases. Members include alginate lyase (EC 4.2.2.3) and chondroitinase B (EC 4.2.2.19). Chondroitinase B is an enzyme that only cleaves the beta-(1,4)-linkage of dermatan sulfate (DS), leading to 4,5-unsaturated dermatan sulfate disaccharides as the product. DS is a highly sulfated, unbranched polysaccharide belonging to a family of glycosaminoglycans (GAGs) composed of alternating hexosamine (gluco- or galactosamine) and uronic acid (D-glucuronic or L-iduronic acid) moieties. DS contains alternating 1,4-beta-D-galactosamine (GalNac) and 1,3-alpha-L-iduronic acid units. The related chondroitin sulfate (CS) contains alternating GalNac and 1,3-beta-D-glucuronic acid units. Alginate lyases (known as either mannuronate (EC 4.2.2.3) or guluronate lyases (EC 4.2.2.11) catalyze the degradation of alginate, a copolymer of alpha-L-guluronate and its C5 epimer beta-D-mannuronate.
pfam07523	Big_3	5.83e-04	414	480	5	67	Bacterial Ig-like domain (group 3). This family consists of bacterial domains with an Ig-like fold. Members of this family are found in a variety of bacterial surface proteins.
pfam14592	Chondroitinas_B	0.001	959	1093	3	134	Chondroitinase B. This family includes chondroitinases. These enzymes cleave the glycosaminoglycan dermatan sulfate.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ANW97669.1	2.35e-222	44	1297	59	1222
BAC87940.1	6.51e-222	44	1297	59	1222
AGI38277.1	1.29e-221	44	1297	59	1222
AGC67199.1	1.29e-221	44	1297	59	1222
ANX00231.1	1.81e-221	44	1297	59	1222

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
1RU4_A	2.41e-27	944	1223	18	292	ChainA, Pectate lyase [Dickeya chrysanthemi]
5OLQ_A	7.65e-12	942	1229	4	324	Rhamnogalacturonanlyase [Bacteroides thetaiotaomicron],5OLQ_B Rhamnogalacturonan lyase [Bacteroides thetaiotaomicron],5OLQ_C Rhamnogalacturonan lyase [Bacteroides thetaiotaomicron],5OLR_A Rhamnogalacturonan lyase [Bacteroides thetaiotaomicron],5OLR_B Rhamnogalacturonan lyase [Bacteroides thetaiotaomicron],5OLR_C Rhamnogalacturonan lyase [Bacteroides thetaiotaomicron],5OLS_A Rhamnogalacturonan lyase [Bacteroides thetaiotaomicron]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P22751	8.75e-57	566	1249	34	663	Pectate disaccharide-lyase OS=Dickeya chrysanthemi OX=556 GN=pelX PE=1 SV=1
P0C1A6	1.25e-28	944	1282	43	371	Pectate lyase L OS=Dickeya chrysanthemi OX=556 GN=pelL PE=3 SV=1
P0C1A7	1.92e-26	944	1223	43	317	Pectate lyase L OS=Dickeya dadantii (strain 3937) OX=198628 GN=pelL PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000247	0.999050	0.000209	0.000179	0.000163	0.000146

TMHMM  Annotations     

start	end
5	27