CAZyme Information: MGYG000002614_01809

Basic Information

• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Phocaeicola
• CAZyme ID: MGYG000002614_01809
• CAZy Family: GH3
• CAZyme Description: Beta-hexosaminidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
995		110651.99	9.7612

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002614	2560607	MAG	China	Asia

• Gene Location: Start: 182; End: 3169 Strand: -

Full Sequence      

MIKHRLLSVLLTVVVSVTAWGQVCPSLIKSAEKDSINCHKWVEEQLQKMTLKEKIGQLFI
HTVSPQITQYGNADIKKAVTEYHIGGLLFSGGQVLNQIEMTNYAQSFAKIPLMLTFDGEW
GLAMRLKQTVSFPRNRVLGCISEDSLLYAYGREVARQCKEIGVHVNFAPVADVDNNPKNP
VINTRSFGSNPQQVARQVAAYAKGLENGGVIAVCKHFPGHGDTETDSHKSLPKLNFDRTR
LDSLELIPFKTAITSGISGMMTGHLLIPALDTQKPASLSHAVVTQLLKNELQFDGLAFTD
ALAMHGVAGYGHPAAQALIAGNDLILVQRNLKKEMDGVLSALKRGSLTEEQITEKCRKVL
TYKYILGLTQTPYIQSGQIMNRINTPEAKELVNTLKKKAVTVISNRDNQLPVSANSSGNL
LVSISKSPSRMHPLYEQLRKSISIQWINLHPDSSKSLLSRIQKANRVIIAIESDHYLRYA
KLLNQVTAQKPTVMTFFTPLAALRGQESMLKKAQAVIAAHTGEAIVQQHVADIIIGKSMA
NGRLSIDLGDTFKAGTGITLNAPSKSISQSAKITGINTSVLNQIDEIALEGIQAKAYPGC
HILVMKKGSIVYDKCFGTVTYESKEKVRPEHLYDLASLSKATGTLLAVMKLYDEGKINLT
DKISKFLPQFKGTNKENITIQELLFHESGLPAYLPFYKDAIDLKSCKGGLFKNRRDACHT
IQVGRNLYACTDFNYRTEWVSPLPSKSYPIQIAENLYIRKEFKDIMLQRIIEASPRSKNY
RYSCLNFMLLKEAVENITRQTMDVFIDSVYFRPMKLERIAYQPLRKFKKEEIIPTVSKDF
LRGSKPLQGFVHDEAAAFLGGVSGNAGMFSSAPEVAAIFQMLLNQGVYNHQRFLSKETCK
LFTTMKSSKSRRGLGFDKPDPNNTHYSPCASEAPACVFGHTGFSGTCAWADPQNDIVMVF
LCNRIYPNPYSQKNLSRLNIRPRIQETIYKALQAP

Enzyme Prediction     

EC	3.2.1.-

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH3	105	327	1.9e-56	0.9814814814814815

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG1472	BglX	1.50e-75	49	423	1	361	Periplasmic beta-glucosidase and related glycosidases [Carbohydrate transport and metabolism].
pfam00933	Glyco_hydro_3	2.45e-75	50	361	1	315	Glycosyl hydrolase family 3 N terminal domain.
PRK03642	PRK03642	4.29e-50	570	993	29	432	putative periplasmic esterase; Provisional
PRK05337	PRK05337	1.56e-37	136	342	82	290	beta-hexosaminidase; Provisional
pfam00144	Beta-lactamase	1.43e-35	584	970	1	314	Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QUT56867.1	0.0	3	992	3	990
QEW35592.1	0.0	3	992	3	990
QQY43102.1	0.0	3	992	3	990
QQY39794.1	0.0	3	992	3	990
ABR37873.1	0.0	3	992	3	990

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6K5J_A	5.85e-64	49	403	11	376	Structureof a glycoside hydrolase family 3 beta-N-acetylglucosaminidase from Paenibacillus sp. str. FPU-7 [Paenibacillaceae]
3SQL_A	3.90e-58	81	428	55	410	CrystalStructure of Glycoside Hydrolase from Synechococcus [Synechococcus sp. PCC 7002],3SQL_B Crystal Structure of Glycoside Hydrolase from Synechococcus [Synechococcus sp. PCC 7002],3SQM_A Crystal Structure of Glycoside Hydrolase from Synechococcus Complexed with N-acetyl-D-glucosamine [Synechococcus sp. PCC 7002],3SQM_B Crystal Structure of Glycoside Hydrolase from Synechococcus Complexed with N-acetyl-D-glucosamine [Synechococcus sp. PCC 7002],3SQM_C Crystal Structure of Glycoside Hydrolase from Synechococcus Complexed with N-acetyl-D-glucosamine [Synechococcus sp. PCC 7002],3SQM_D Crystal Structure of Glycoside Hydrolase from Synechococcus Complexed with N-acetyl-D-glucosamine [Synechococcus sp. PCC 7002]
3BMX_A	5.51e-57	30	422	27	457	Beta-N-hexosaminidase(YbbD) from Bacillus subtilis [Bacillus subtilis],3BMX_B Beta-N-hexosaminidase (YbbD) from Bacillus subtilis [Bacillus subtilis],3NVD_A Structure of YBBD in complex with pugnac [Bacillus subtilis],3NVD_B Structure of YBBD in complex with pugnac [Bacillus subtilis]
3LK6_A	1.62e-56	30	422	1	431	ChainA, Lipoprotein ybbD [Bacillus subtilis],3LK6_B Chain B, Lipoprotein ybbD [Bacillus subtilis],3LK6_C Chain C, Lipoprotein ybbD [Bacillus subtilis],3LK6_D Chain D, Lipoprotein ybbD [Bacillus subtilis]
4GYJ_A	2.80e-56	30	422	31	461	Crystalstructure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1) [Bacillus subtilis subsp. subtilis str. 168],4GYJ_B Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1) [Bacillus subtilis subsp. subtilis str. 168],4GYK_A Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1211) [Bacillus subtilis subsp. subtilis str. 168],4GYK_B Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1211) [Bacillus subtilis subsp. subtilis str. 168]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P40406	3.02e-56	30	422	27	457	Beta-hexosaminidase OS=Bacillus subtilis (strain 168) OX=224308 GN=nagZ PE=1 SV=1
P48823	1.50e-48	74	416	54	429	Beta-hexosaminidase A OS=Pseudoalteromonas piscicida OX=43662 GN=cht60 PE=1 SV=1
P77619	8.20e-41	570	974	29	406	Putative D-alanyl-D-alanine carboxypeptidase OS=Escherichia coli (strain K12) OX=83333 GN=yfeW PE=1 SV=2
Q8XBJ0	3.05e-39	570	974	29	406	Putative D-alanyl-D-alanine carboxypeptidase OS=Escherichia coli O157:H7 OX=83334 GN=yfeW PE=3 SV=1
Q7WUL3	2.53e-38	41	422	18	408	Beta-N-acetylglucosaminidase/beta-glucosidase OS=Cellulomonas fimi OX=1708 GN=nag3 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000852	0.997244	0.001312	0.000201	0.000186	0.000188

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002614_01809.