CAZyme Information: MGYG000002621_00910

Basic Information

• Species: Bacteroides ndongoniae
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides ndongoniae
• CAZyme ID: MGYG000002621_00910
• CAZy Family: PL30
• CAZyme Description: Chondroitinase-AC

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
800	MGYG000002621_6|CGC3	90367.07	7.5042

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002621	3633256	MAG	China	Asia

• Gene Location: Start: 102024; End: 104426 Strand: -

Full Sequence      

MKNNVLNIGIGLFFALNCFCLGEVAAQNREAQMAERCYLRYYQEARQVQDAAKGQAIENF
RQFYAKHTYLNLNNYSKDYRPYLETLQADGTFADLHDKDAGKVVGGNSANSGGSITEGYY
RLWAISEAFRRGELDWQKDGELWRRCQKAIVHYGELEISRGNEWYRFHASCFALPEAAVN
IYFCHLPQMDAVEKGKTDDFLLKKACDMLKMIALQAWTQPYRKDETDLNVVSEERFRKHV
WWVGGNGVGYRALLQAAFMYRSIPMIDVLAEVCRKGITPTSQTTYDDSFWNEGFTADGAG
WGHGRQCLVWGYPIDGTRGALGILTLLKGTPWAQQLDRRNVEALMNYFRGANFYYYKGYK
LACVDRSSMLYMDAPAAIPYSSLLDNVLANWIESFTPDEQEELKRLRSEIPSMNINMNGD
GRYNGTRWFFNNDDLVKKNDRYHVIANMASVRCDGLESAYTFADAFNYYTNDGALMFQRR
GNEYRNVYGAYDVTAFPGVTAREGMEQLKPVENWRGYCSKYNFAGAATSGGENAAAGFVF
EKMNASDKKGVNDKGRGGADRVIYGVKAHKAAFILGDYVVALGAGITNLTPEVNGNIRTT
LDQTERTGNVFVHHGKGIDWIVQRGGFAYSAFPEYQKRMHYVCETKRTDWVKMNPANRGR
KNLPAEVDMLRLWIDHGTTPTDDTYGYAVYCGDGLPADRYPFRVLRNDTTLQAVRSTDGR
VTGAVFYRADEGLKAKHLQLSVSAPCVVLIEETSEGTLLSVTDACMDKNLKEIRVNWNGK
TYICPMSQGELCGKPTVVKL

Enzyme Prediction     

No EC number prediction in MGYG000002621_00910.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
PL30	83	763	4.4e-287	0.9901685393258427

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd01083	GAG_Lyase	8.71e-50	82	763	28	692	Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase.
pfam02278	Lyase_8	2.66e-44	426	690	1	248	Polysaccharide lyase family 8, super-sandwich domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.
pfam02884	Lyase_8_C	4.38e-11	705	763	1	58	Polysaccharide lyase family 8, C-terminal beta-sandwich domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QUT37261.1	7.15e-310	1	800	1	820
QQA29924.1	5.80e-309	1	800	1	820
QUT61434.1	5.80e-309	1	800	1	820
BBK86575.1	5.80e-309	1	800	1	820
QUT65873.1	2.69e-307	1	800	1	820

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.001417	0.543100	0.454287	0.000465	0.000387	0.000319

TMHMM  Annotations     

start	end
5	27