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CAZyme Information: MGYG000002663_01340

You are here: Home > Sequence: MGYG000002663_01340

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Prevotella sp900772835
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotella; Prevotella sp900772835
CAZyme ID MGYG000002663_01340
CAZy Family GH137
CAZyme Description Beta-galactosidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1358 MGYG000002663_56|CGC1 154467.27 8.3698
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002663 2098573 MAG United Republic of Tanzania Africa
Gene Location Start: 8638;  End: 12714  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.31 3.2.1.185

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH137 34 380 3.3e-145 0.9882352941176471
GH2 388 830 3.6e-72 0.5079787234042553
CBM57 1049 1207 1.3e-34 0.9863945578231292

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3250 LacZ 2.99e-37 381 797 4 426
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
pfam11721 Malectin 1.07e-24 1047 1207 1 164
Di-glucose binding within endoplasmic reticulum. Malectin is a membrane-anchored protein of the endoplasmic reticulum that recognizes and binds Glc2-N-glycan. It carries a signal peptide from residues 1-26, a C-terminal transmembrane helix from residues 255-274, and a highly conserved central part of approximately 190 residues followed by an acidic, glutamate-rich region. Carbohydrate-binding is mediated by the four aromatic residues, Y67, Y89, Y116, and F117 and the aspartate at D186. NMR-based ligand-screening studies has shown binding of the protein to maltose and related oligosaccharides, on the basis of which the protein has been designated "malectin", and its endogenous ligand is found to be Glc2-high-mannose N-glycan.
PRK10340 ebgA 5.59e-24 434 804 112 472
cryptic beta-D-galactosidase subunit alpha; Reviewed
pfam02836 Glyco_hydro_2_C 5.31e-17 662 939 5 297
Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
PRK10150 PRK10150 1.21e-15 431 872 65 536
beta-D-glucuronidase; Provisional

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QUT23622.1 0.0 35 1358 23 1396
QRN01915.1 0.0 35 1358 23 1399
QUR43084.1 0.0 35 1358 23 1399
QNL37683.1 0.0 35 1358 23 1399
QGT69996.1 0.0 35 1358 23 1399

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5MUI_A 3.48e-176 35 384 29 378
Glycosidehydrolase BT_0996 [Bacteroides thetaiotaomicron VPI-5482]
5MT2_A 1.50e-169 35 384 29 378
Glycosidehydrolase BT_0996 [Bacteroides thetaiotaomicron VPI-5482],5MUJ_A BT0996 RGII Chain B Complex [Bacteroides thetaiotaomicron VPI-5482]
6D50_A 2.50e-38 380 1194 24 868
Bacteroidesuniforms beta-glucuronidase 2 bound to D-glucaro-1,5-lactone [Bacteroides uniformis str. 3978 T3 ii],6D50_B Bacteroides uniforms beta-glucuronidase 2 bound to D-glucaro-1,5-lactone [Bacteroides uniformis str. 3978 T3 ii]
5UJ6_A 5.60e-38 388 1194 24 860
CrystalStructure of Bacteroides Uniformis beta-glucuronidase [Bacteroides uniformis str. 3978 T3 ii],5UJ6_B Crystal Structure of Bacteroides Uniformis beta-glucuronidase [Bacteroides uniformis str. 3978 T3 ii],6NZG_A Bacteroides uniformis beta-glucuronidase 2 covalently bound to cyclophellitol-6-carboxylate aziridine [Bacteroides uniformis],6NZG_B Bacteroides uniformis beta-glucuronidase 2 covalently bound to cyclophellitol-6-carboxylate aziridine [Bacteroides uniformis]
6D8G_A 1.33e-37 380 1194 24 868
D341AD367A calcium binding mutant of Bacteroides uniformis beta-glucuronidase 2 [Bacteroides uniformis str. 3978 T3 ii],6D8G_B D341A D367A calcium binding mutant of Bacteroides uniformis beta-glucuronidase 2 [Bacteroides uniformis str. 3978 T3 ii]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
T2KPJ7 5.28e-36 384 1028 46 718
Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_21970 PE=2 SV=1
T2KM09 1.83e-26 358 806 19 456
Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22050 PE=2 SV=2
A7LXS9 5.58e-26 431 776 102 437
Beta-galactosidase BoGH2A OS=Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC 11153) OX=411476 GN=BACOVA_02645 PE=1 SV=1
P26257 9.24e-23 445 981 69 586
Beta-galactosidase OS=Thermoanaerobacterium thermosulfurigenes OX=33950 GN=lacZ PE=1 SV=1
Q56307 5.31e-21 392 785 74 450
Beta-galactosidase OS=Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) OX=243274 GN=lacZ PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000266 0.999147 0.000149 0.000153 0.000142 0.000130

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002663_01340.