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CAZyme Information: MGYG000002674_00248

You are here: Home > Sequence: MGYG000002674_00248

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae; Alistipes;
CAZyme ID MGYG000002674_00248
CAZy Family PL13
CAZyme Description Heparin lyase I
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
381 MGYG000002674_10|CGC1 42505.02 8.4317
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002674 2150198 MAG Canada North America
Gene Location Start: 11840;  End: 12985  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 4.2.2.7

CAZyme Signature Domains help

Family Start End Evalue family coverage
PL13 24 377 4e-174 0.9834710743801653

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam14099 Polysacc_lyase 4.83e-12 69 365 28 200
Polysaccharide lyase. This family includes heparin lyase I, EC:4.2.2.7. Heparin lyase I depolymerizes heparin by cleaving the glycosidic linkage next to an iduronic acid moiety. The structure of heparin lyase I consists of a beta-jelly roll domain with a long, deep substrate-binding groove and an unusual thumb domain containing many basic residues extending from the main body of the enzyme. This family also includes glucuronan lyase, EC:4.2.2.14. The structure glucuronan lyase is a beta-jelly roll.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
CBK62841.1 1.03e-198 8 379 2 377
ADL62736.1 7.63e-169 21 373 22 389
QUT82562.1 2.38e-165 23 378 25 392
QDM12118.1 2.38e-165 23 378 25 392
QRQ56254.1 6.80e-165 23 378 25 392

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3ILR_A 1.32e-165 23 378 3 370
Structureof Heparinase I from Bacteroides thetaiotaomicron in complex with tetrasaccharide product [Bacteroides thetaiotaomicron]
3IKW_A 1.52e-165 23 378 7 374
Structureof Heparinase I from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron]
3IMN_A 9.52e-163 23 378 9 376
Crystalstructure of heparin lyase I from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron],3IN9_A Crystal structure of heparin lyase I complexed with disaccharide heparin [Bacteroides thetaiotaomicron]
3INA_A 3.14e-161 23 378 9 376
Crystalstructure of heparin lyase I H151A mutant complexed with a dodecasaccharide heparin [Bacteroides thetaiotaomicron]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q05819 3.64e-149 19 377 19 381
Heparin lyase I OS=Pedobacter heparinus OX=984 PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000357 0.998947 0.000204 0.000181 0.000159 0.000144

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002674_00248.