CAZyme Information: MGYG000002681_01524

Basic Information

• Species: UMGS1975 sp900546685
• Lineage: Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; QAND01; UMGS1975; UMGS1975 sp900546685
• CAZyme ID: MGYG000002681_01524
• CAZy Family: GT2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
573		64361.36	6.3429

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002681	1889419	MAG	Canada	North America

• Gene Location: Start: 623; End: 2344 Strand: -

Full Sequence      

MANFKQALRMGLKGVKLAVTKGPKTAWRLTREKTQRMQACRQMAALHMISDEERARQKSA
QFANPVKISILTPLYNTPEPFLRALIASLKAQTYPNWELCAADGSDDAHAYVGRICREEA
EKDPRIVYSHLEENGGISDNTNACIRLASGAYFGLLDHDDILHESALYEVMRAIEEKGAD
FIYTDEVKFDGDVEKASDFNFKPGFGKDELRSHNYICHFTCYSRALLESTGAWYRPAFDG
SQDHDIVLRLTERARCIVHIPKVLYYWRVHEQSVSMDLSTKQYAVDAAIHAVAEQLQRAG
EKGQVRSNLPYQTIYRIRYEVDKELVSVLLYDAVSPEQAQRCVDRLIQSTAWRPLELVCY
EQAVPRRCPEGVALKPVPKQERLADSLDEMARAAGGKYLCLFASALQPEDEHWLEEMAML
CQRPDVCAVGAKCYDESDNVLCAGLALDGDKPDLIAALCRGIHRDQQGFEAMLRYVRNVT
ALDGACFLVKKQTWQALGGFHAAADGYETVEFCLGGVKQGLWNVWTPFAECKLAEAPAAG
PCRDAGAFLQRWSKQAGEPDPYYHPNLKKLGLL

Enzyme Prediction     

No EC number prediction in MGYG000002681_01524.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	69	229	2.7e-24	0.9823529411764705

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd04184	GT2_RfbC_Mx_like	5.44e-89	67	269	2	202	Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis. The rfbC gene encodes a predicted protein of 1,276 amino acids, which is required for O-antigen biosynthesis in Myxococcus xanthus. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.
cd06433	GT_2_WfgS_like	2.44e-25	69	273	1	199	WfgS and WfeV are involved in O-antigen biosynthesis. Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.
pfam00535	Glycos_transf_2	7.43e-24	69	227	1	164	Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.
cd00761	Glyco_tranf_GTA_type	1.35e-21	70	259	1	156	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.
COG0463	WcaA	1.40e-18	67	276	4	200	Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QRO35980.1	8.61e-171	46	570	43	553
QBF76213.1	8.61e-171	46	570	43	553
CAB1243278.1	1.42e-127	13	567	447	1023
ACD24731.1	1.46e-122	13	567	521	1096
CDH92150.1	1.46e-122	13	567	521	1096

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P55465	9.53e-59	68	567	368	888	Uncharacterized protein y4gI OS=Sinorhizobium fredii (strain NBRC 101917 / NGR234) OX=394 GN=NGR_a03550 PE=4 SV=1
Q50864	1.52e-47	55	567	308	831	O-antigen biosynthesis protein RfbC OS=Myxococcus xanthus OX=34 GN=rfbC PE=4 SV=1
P71059	2.46e-09	68	275	5	219	Uncharacterized glycosyltransferase EpsJ OS=Bacillus subtilis (strain 168) OX=224308 GN=epsJ PE=2 SV=1
Q92IF9	7.80e-08	55	184	282	406	Uncharacterized glycosyltransferase RC0461 OS=Rickettsia conorii (strain ATCC VR-613 / Malish 7) OX=272944 GN=RC0461 PE=3 SV=1
Q4UM29	4.11e-07	55	188	282	410	Uncharacterized glycosyltransferase RF_0543 OS=Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) OX=315456 GN=RF_0543 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000051	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002681_01524.