CAZyme Information: MGYG000002691_00499

Basic Information

• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Oscillospiraceae; Dysosmobacter
• CAZyme ID: MGYG000002691_00499
• CAZy Family: GT5
• CAZyme Description: Glycogen synthase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
653	MGYG000002691_4|CGC1	72092.67	4.8578

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002691	2941528	MAG	Canada	North America

• Gene Location: Start: 88278; End: 90239 Strand: -

Full Sequence      

MKILYATSEAVPFCKTGGLADVAGSLPPALAQQGAEVAVVLPLYRRGRERFGGELKFECY
DFVNLAWRHSYCGLFSLERDGVTWYFLDNEQYFDRPDLYGYMDDGERFGFFSRAVVRMLP
HFKFWPDVIHCNDWQTALVPIYLKDDGVREDRFRSIRTALTIHNIEYQGRYAKDTLGDLF
GLDYGWAADGTIMMDGDVNLLKGAILCADAVNAVSPTYANELKMAYFAHHMESIMNRCDY
KLSGVLNGIDMNLYNPETDERIPVRYSVQDMSGKDADKAELQKIMGLHQEPHTPIVAIVS
RLVSHKGLDLICEVLHDMMELPMQLVVLGKGDRKYEDFFNWAAQQYPGRMAVRLDYNEAL
SMSIYSGADLFLMPSKSEPCGLSQMIAMRYGTIPIVRETGGLKDTVQPYEAWRDAGNGFS
FRNYASGDMLYVIREAVYLYKDYPEAFGRLRQRAMSCDFSWARSAHDYLRIYSNITGQPM
PVIASEEAPAPTAEAAPVEEAPVEATPVEAAPAEETPVEAAPVEETPVEAAPVEETPVEA
VPVEEAPVEATPVETAPAEEAPAQPAPVEAASAEEAPAPAVPEKKTRRTAAKKPAAKRTT
TRKSTAKSTSEKSAAAKSKTSAATAEAAKSTAKKEKSTKKGSAAKSAKEDAAE

Enzyme Prediction     

EC	2.4.1.21

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT5	2	473	3.8e-169	0.9957627118644068

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd03791	GT5_Glycogen_synthase_DULL1-like	0.0	2	472	1	472	Glycogen synthase GlgA and similar proteins. This family is most closely related to the GT5 family of glycosyltransferases. Glycogen synthase (EC:2.4.1.21) catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family includes starch synthases of plants, such as DULL1 in Zea mays and glycogen synthases of various organisms.
PRK00654	glgA	0.0	1	478	1	466	glycogen synthase GlgA.
TIGR02095	glgA	0.0	1	475	1	473	glycogen/starch synthase, ADP-glucose type. This family consists of glycogen (or starch) synthases that use ADP-glucose (EC 2.4.1.21), rather than UDP-glucose (EC 2.4.1.11) as in animals, as the glucose donor. This enzyme is found in bacteria and plants. Whether the name given is glycogen synthase or starch synthase depends on context, and therefore on substrate. [Energy metabolism, Biosynthesis and degradation of polysaccharides]
COG0297	GlgA	0.0	1	481	1	484	Glycogen synthase [Carbohydrate transport and metabolism].
PRK14099	PRK14099	1.46e-105	1	481	4	485	glycogen synthase GlgA.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QUO39419.1	1.95e-311	1	502	1	494
BCK84472.1	5.67e-310	1	501	1	501
QCI58885.1	1.57e-305	1	496	1	493
BAL00800.1	2.34e-277	1	487	1	487
QNL45767.1	2.10e-247	2	477	22	497

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3D1J_A	1.72e-90	1	472	1	473	ChainA, Glycogen synthase [Escherichia coli]
2QZS_A	4.25e-90	1	472	1	473	CrystalStructure of Wild-type E.coli GS in complex with ADP and Glucose(wtGSb) [Escherichia coli],2R4T_A Crystal Structure of Wild-type E.coli GS in Complex with ADP and Glucose(wtGSc) [Escherichia coli],2R4U_A Crystal Structure of Wild-type E.coli GS in complex with ADP and Glucose(wtGSd) [Escherichia coli],3GUH_A Crystal Structure of Wild-type E.coli GS in complex with ADP and DGM [Escherichia coli K-12]
3COP_A	3.25e-89	1	472	1	473	ChainA, Glycogen synthase [Escherichia coli],3CX4_A Chain A, Glycogen synthase [Escherichia coli]
6GNE_A	8.93e-83	1	473	10	495	Catalyticdomain of Starch Synthase IV from Arabidopsis thaliana bound to ADP and acarbose [Arabidopsis thaliana],6GNE_B Catalytic domain of Starch Synthase IV from Arabidopsis thaliana bound to ADP and acarbose [Arabidopsis thaliana]
4HLN_A	7.65e-80	2	472	126	622	Structureof barley starch synthase I in complex with maltooligosaccharide [Hordeum vulgare]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
A4IS20	1.06e-150	1	475	1	474	Glycogen synthase OS=Geobacillus thermodenitrificans (strain NG80-2) OX=420246 GN=glgA PE=3 SV=1
O08328	4.26e-150	1	475	1	474	Glycogen synthase OS=Geobacillus stearothermophilus OX=1422 GN=glgA PE=3 SV=1
Q9CHM9	2.70e-149	1	475	1	478	Glycogen synthase OS=Lactococcus lactis subsp. lactis (strain IL1403) OX=272623 GN=glgA PE=3 SV=2
Q5FL65	1.43e-148	1	477	1	476	Glycogen synthase OS=Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM) OX=272621 GN=glgA PE=3 SV=1
B9J2G5	1.29e-146	1	475	1	474	Glycogen synthase OS=Bacillus cereus (strain Q1) OX=361100 GN=glgA PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000006	0.000037	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002691_00499.