logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000002717_01553

You are here: Home > Sequence: MGYG000002717_01553

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides;
CAZyme ID MGYG000002717_01553
CAZy Family GH28
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1068 119468.75 6.5087
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002717 5602088 MAG Canada North America
Gene Location Start: 4840;  End: 8046  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.67 3.2.1.-

CAZyme Signature Domains help

Family Start End Evalue family coverage
PL11 476 1059 5.8e-267 0.9811320754716981
GH28 79 441 2e-67 0.9323076923076923

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd10318 RGL11 0.0 478 1052 2 564
Rhamnogalacturonan lyase of the polysaccharide lyase family 11. The rhamnogalacturonan lyase of the polysaccharide lyase family 11 (RGL11) cleaves glycoside bonds in polygalacturonan as well as RG (rhamnogalacturonan) type-I through a beta-elimination reaction. Functionally characterized members of this family, YesW and YesX from Bacillus subtilis, cleave glycoside bonds between rhamnose and galacturonic acid residues in the RG-I region of plant cell wall pectin. YesW and YesX work synergistically, with YesW cleaving the glycoside bond of the RG chain endolytically, and YesX converting the resultant oligosaccharides through an exotype reaction. This domain is sometimes found in architectures with non-catalytic carbohydrate-binding modules (CBMs). There are two types of RG lyases, which both cleave the alpha-1,4 bonds of the RG-I main chain through a beta-elimination reaction, but belong to two structurally unrelated polysaccharide lyase (PL) families, 4 and 11.
COG5434 Pgu1 9.08e-78 21 367 41 395
Polygalacturonase [Carbohydrate transport and metabolism].
pfam18370 RGI_lyase 8.83e-23 476 559 2 83
Rhamnogalacturonan I lyases beta-sheet domain. This is the beta-sheet domain found in rhamnogalacturonan (RG) lyases, which are responsible for an initial cleavage of the RG type I (RG-I) region of plant cell wall pectin. Polysaccharide lyase family 11 carrying this domain, such as YesW (EC:4.2.2.23) and YesX (EC:4.2.2.24), cleave glycoside bonds between rhamnose and galacturonic acid residues in RG-I through a beta-elimination reaction. Other family members carrying this domain are hemagglutinin A, lysine gingipain (Kgp) and Chitinase C (EC:3.2.1.14).
PLN03003 PLN03003 6.75e-11 57 335 26 257
Probable polygalacturonase At3g15720
pfam00295 Glyco_hydro_28 5.54e-10 202 379 77 249
Glycosyl hydrolases family 28. Glycosyl hydrolase family 28 includes polygalacturonase EC:3.2.1.15 as well as rhamnogalacturonase A(RGase A), EC:3.2.1.-. These enzymes are important in cell wall metabolism.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QDO69321.1 0.0 1 1068 1 1067
ALJ61442.1 0.0 456 1068 32 666
QUT92983.1 0.0 456 1068 32 666
ALK86406.1 0.0 468 1068 9 618
QJR54146.1 0.0 468 1068 24 633

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5OLP_A 1.23e-246 30 460 20 450
Galacturonidase[Bacteroides thetaiotaomicron VPI-5482],5OLP_B Galacturonidase [Bacteroides thetaiotaomicron VPI-5482]
4CAG_A 1.06e-222 476 1059 10 580
Bacilluslicheniformis Rhamnogalacturonan Lyase PL11 [Bacillus licheniformis]
2Z8R_A 4.50e-220 476 1058 4 572
Crystalstructure of rhamnogalacturonan lyase YesW at 1.40 A resolution [Bacillus subtilis],2Z8R_B Crystal structure of rhamnogalacturonan lyase YesW at 1.40 A resolution [Bacillus subtilis],2Z8S_A Crystal structure of rhamnogalacturonan lyase YesW complexed with digalacturonic acid [Bacillus subtilis],2Z8S_B Crystal structure of rhamnogalacturonan lyase YesW complexed with digalacturonic acid [Bacillus subtilis],2ZUX_A Crystal structure of rhamnogalacturonan lyase YesW complexed with rhamnose [Bacillus subtilis],2ZUX_B Crystal structure of rhamnogalacturonan lyase YesW complexed with rhamnose [Bacillus subtilis]
2ZUY_A 1.24e-216 474 1059 5 594
Crystalstructure of exotype rhamnogalacturonan lyase YesX [Bacillus subtilis]
3JUR_A 2.17e-82 45 377 18 359
Thecrystal structure of a hyperthermoactive Exopolygalacturonase from Thermotoga maritima [Thermotoga maritima],3JUR_B The crystal structure of a hyperthermoactive Exopolygalacturonase from Thermotoga maritima [Thermotoga maritima],3JUR_C The crystal structure of a hyperthermoactive Exopolygalacturonase from Thermotoga maritima [Thermotoga maritima],3JUR_D The crystal structure of a hyperthermoactive Exopolygalacturonase from Thermotoga maritima [Thermotoga maritima]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
O31526 6.77e-219 476 1058 41 609
Rhamnogalacturonan endolyase YesW OS=Bacillus subtilis (strain 168) OX=224308 GN=yesW PE=1 SV=1
O31527 5.16e-216 474 1059 5 594
Rhamnogalacturonan exolyase YesX OS=Bacillus subtilis (strain 168) OX=224308 GN=yesX PE=1 SV=1
A7PZL3 1.44e-24 57 371 65 362
Probable polygalacturonase OS=Vitis vinifera OX=29760 GN=GSVIVT00026920001 PE=1 SV=1
P15922 6.15e-20 57 330 154 444
Exo-poly-alpha-D-galacturonosidase OS=Dickeya chrysanthemi OX=556 GN=pehX PE=1 SV=1
P27644 8.11e-16 213 406 25 230
Polygalacturonase OS=Rhizobium radiobacter OX=358 GN=pgl PE=2 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.041893 0.628481 0.328692 0.000341 0.000280 0.000286

TMHMM  Annotations      download full data without filtering help

start end
5 27