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CAZyme Information: MGYG000002819_00876
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Veillonella tobetsuensis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_C; Negativicutes; Veillonellales; Veillonellaceae; Veillonella; Veillonella tobetsuensis | |||||||||||
| CAZyme ID | MGYG000002819_00876 | |||||||||||
| CAZy Family | GH23 | |||||||||||
| CAZyme Description | Soluble lytic murein transglycosylase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 29910; End: 30464 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH23 | 45 | 175 | 1.1e-29 | 0.837037037037037 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd16896 | LT_Slt70-like | 2.24e-69 | 33 | 175 | 1 | 146 | uncharacterized lytic transglycosylase subfamily with similarity to Slt70. Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
| cd13401 | Slt70-like | 2.70e-59 | 31 | 179 | 1 | 152 | 70kDa soluble lytic transglycosylase (Slt70) and similar proteins. Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda. |
| cd00254 | LT-like | 2.45e-37 | 51 | 174 | 1 | 111 | lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
| COG0741 | MltE | 3.68e-35 | 27 | 184 | 130 | 291 | Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell wall/membrane/envelope biogenesis]. |
| pfam01464 | SLT | 1.36e-30 | 43 | 150 | 4 | 108 | Transglycosylase SLT domain. This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| ARF99123.1 | 4.64e-130 | 1 | 184 | 1 | 184 |
| BBU36008.1 | 1.30e-111 | 1 | 181 | 1 | 181 |
| VEG93728.1 | 1.30e-111 | 1 | 181 | 1 | 181 |
| BBU34602.1 | 1.30e-111 | 1 | 181 | 1 | 181 |
| CAB1276067.1 | 2.81e-106 | 1 | 181 | 1 | 181 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6FBT_A | 2.93e-25 | 32 | 182 | 445 | 594 | ChainA, Lytic murein transglycosylase [Pseudomonas aeruginosa] |
| 5OHU_A | 3.02e-25 | 32 | 182 | 474 | 623 | TheX-ray Structure of Lytic Transglycosylase Slt from Pseudomonas aeruginosa [Pseudomonas aeruginosa] |
| 5MPQ_A | 7.06e-25 | 36 | 184 | 416 | 563 | BulgecinA: The key to a broad-spectrum inhibitor that targets lytic transglycosylases [Neisseria meningitidis] |
| 5O1J_A | 7.11e-25 | 36 | 184 | 420 | 567 | Lytictransglycosylase in action [Neisseria meningitidis MC58] |
| 6FPN_B | 7.18e-25 | 36 | 184 | 426 | 573 | Lytictransglycosylase in action [Neisseria meningitidis MC58] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P39434 | 3.65e-23 | 32 | 182 | 476 | 631 | Soluble lytic murein transglycosylase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=slt PE=3 SV=2 |
| P0AGC4 | 4.32e-22 | 32 | 182 | 476 | 631 | Soluble lytic murein transglycosylase OS=Escherichia coli O157:H7 OX=83334 GN=slt PE=3 SV=1 |
| P0AGC3 | 4.32e-22 | 32 | 182 | 476 | 631 | Soluble lytic murein transglycosylase OS=Escherichia coli (strain K12) OX=83333 GN=slt PE=1 SV=1 |
| O31976 | 9.56e-18 | 31 | 170 | 1417 | 1538 | SPbeta prophage-derived uncharacterized transglycosylase YomI OS=Bacillus subtilis (strain 168) OX=224308 GN=yomI PE=3 SV=2 |
| O64046 | 9.56e-18 | 31 | 170 | 1417 | 1538 | Probable tape measure protein OS=Bacillus phage SPbeta OX=66797 GN=yomI PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.777769 | 0.174349 | 0.047166 | 0.000174 | 0.000142 | 0.000409 |