CAZyme Information: MGYG000002900_01463

Basic Information

• Species: Actinomyces urogenitalis
• Lineage: Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Actinomycetaceae; Actinomyces; Actinomyces urogenitalis
• CAZyme ID: MGYG000002900_01463
• CAZy Family: GT4
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
469		50232.08	9.1685

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002900	2460697	MAG	United States	North America

• Gene Location: Start: 10638; End: 12047 Strand: -

Full Sequence      

MSTARLRDRVRQVRRQLTTAPDLARRRGVLLATRIHLPEAAAASFRLDGVEKALAGHDVP
VRVLTTTPPAAAGAGNGTAKDSQEAQPAYRDPEGVSVSRWPALRDASGYLRGYVPYMSFD
VPLLGRLLVQPRPDAVLVEPPPTTGVVVRVAAALRGLPYVWYAPDVWSVAATSTSAPGVV
LAAVRAMESFAVRGAQRVIAVNEEVADKVRQLGAHDVEVVPNGIDTSVFDTAGDLPRAQE
RQEMGITGPYAVYAGTASEWQDAGVFARALAAVRRDHPSAQVLYLGQGSDWEAIAQAAAQ
IPAGADGAPAVVMHGLMPPEQAARWQRGAACALVSIKPGLGYDFAYPTKVLAALACGTPV
LYAGPGPVTDDVAAHDLGWVARHEDGDVARALSEAFAADARLDPAGRQERAARLHGWVEA
HRSLRATGEAVAHLMREVVLERRARPDLLTRLGERLRQVRQARDVRERR

Enzyme Prediction     

No EC number prediction in MGYG000002900_01463.

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd03794	GT4_WbuB-like	5.72e-38	29	413	2	374	Escherichia coli WbuB and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.
cd03801	GT4_PimA-like	2.30e-18	124	436	74	366	phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.
COG0438	RfaB	1.97e-17	87	442	42	381	Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis].
cd03798	GT4_WlbH-like	1.42e-14	53	420	26	365	Bordetella parapertussis WlbH and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.
cd03821	GT4_Bme6-like	5.52e-09	188	437	146	377	Brucella melitensis Bme6 and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QPL06498.1	2.56e-199	31	443	1	399
AYD90266.1	1.32e-193	15	444	20	463
VEG75890.1	8.21e-193	24	444	13	416
BDA63700.1	5.75e-187	25	439	5	412
VEI16149.1	9.99e-181	26	439	6	412

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000062	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002900_01463.