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CAZyme Information: MGYG000002949_01313

You are here: Home > Sequence: MGYG000002949_01313

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species UMGS1251 sp900549995
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; UMGS1251; UMGS1251 sp900549995
CAZyme ID MGYG000002949_01313
CAZy Family GH18
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
611 68905.13 6.3438
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002949 4765419 MAG United States North America
Gene Location Start: 65998;  End: 67833  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000002949_01313.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH18 310 597 5.6e-36 0.7804054054054054

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd02874 GH18_CFLE_spore_hydrolase 1.71e-69 313 606 12 313
Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis.
COG3858 YaaH 4.01e-47 307 606 107 418
Spore germination protein YaaH [Cell cycle control, cell division, chromosome partitioning].
pfam00704 Glyco_hydro_18 7.44e-25 363 597 73 306
Glycosyl hydrolases family 18.
cd06549 GH18_trifunctional 9.76e-25 326 603 24 298
GH18 domain of an uncharacterized family of bacterial proteins, which share a common three-domain architecture: an N-terminal glycosyl hydrolase family 18 (GH18) domain, a glycosyl transferase family 2 domain, and a C-terminal polysaccharide deacetylase domain.
smart00636 Glyco_18 1.09e-24 309 596 10 332
Glyco_18 domain.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QUO31452.1 1.23e-244 73 611 88 650
QRT51337.1 2.57e-241 78 611 70 619
QEK19554.1 3.79e-237 72 611 106 664
QDW72590.1 2.59e-236 73 611 102 659
QRO36968.1 2.64e-228 72 611 120 678

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3CZ8_A 8.57e-25 377 595 88 308
ChainA, Putative sporulation-specific glycosylase ydhD [Bacillus subtilis subsp. subtilis str. 168],3CZ8_B Chain B, Putative sporulation-specific glycosylase ydhD [Bacillus subtilis subsp. subtilis str. 168]
4S3K_A 2.80e-20 342 606 158 423
ChainA, Spore germination protein YaaH [Priestia megaterium QM B1551]
4S3J_A 2.81e-18 368 608 180 423
Crystalstructure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876],4S3J_B Crystal structure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876],4S3J_C Crystal structure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876]
5JH8_A 9.84e-17 382 608 86 312
Crystalstructure of chitinase from Chromobacterium violaceum ATCC 12472 [Chromobacterium violaceum ATCC 12472]
6INX_A 2.58e-06 377 596 79 327
Structuralinsights into a novel glycoside hydrolase family 18 N-acetylglucosaminidase from Paenibacillus barengoltzii [Paenibacillus barengoltzii]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
O32258 2.56e-25 338 608 63 341
Uncharacterized glycosylase YvbX OS=Bacillus subtilis (strain 168) OX=224308 GN=yvbX PE=3 SV=1
O05495 1.02e-24 377 603 180 409
Putative sporulation-specific glycosylase YdhD OS=Bacillus subtilis (strain 168) OX=224308 GN=ydhD PE=1 SV=2
P37531 6.14e-20 378 611 186 424
Cortical fragment-lytic enzyme OS=Bacillus subtilis (strain 168) OX=224308 GN=sleL PE=1 SV=2
P0DPJ9 3.55e-18 353 608 159 422
Cortical fragment-lytic enzyme OS=Bacillus anthracis OX=1392 GN=sleL PE=2 SV=1
Q9K3E4 3.59e-16 368 608 179 422
Cortical fragment-lytic enzyme OS=Bacillus cereus OX=1396 GN=sleL PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.999736 0.000259 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      download full data without filtering help

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