CAZyme Information: MGYG000002949_02977

Basic Information

• Species: UMGS1251 sp900549995
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; UMGS1251; UMGS1251 sp900549995
• CAZyme ID: MGYG000002949_02977
• CAZy Family: GH36
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
531	MGYG000002949_46|CGC1	62142.01	4.8511

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002949	4765419	MAG	United States	North America

• Gene Location: Start: 19276; End: 20871 Strand: -

Full Sequence      

MEHIIRYPDYITVETENWKKGMKMQGEVFSLDHVQIGFEQTEEELEIFCTAENERVRMIQ
LRWEMNVPEHTEFLGDEWERTYGQTQWMHMNGCRFMPWYFLADDGREVWGYGVKVRPSAM
CMWSADKKGVTLYLDVRCGGTGVLLKGRKLKAAQIVSRVYNSVSAFEAARQFCAVLCEDP
ILPDNPVYGSNNWYYAYGDSSEEEILSDARYLADLTEGIKNRPYLVIDDCWQEHHRLDEY
NGGPWRKGNEKFPDMKNLADQIKEMGLHTGIWVRFLLNEEENIEEGWRLSHNGCLDPSHP
QVKRYIKKDIETICEWGFQLIKHDFSTYDILGKWGFQMQPLATEDGWHFYEEGRTTAEII
VDFYQLILDASRSYRTLILGCNTIGHLGAGLMHMNRTGDDTSGFVWERTRKMGVNTLAFR
MPHHRTFYDIDADCVGINGEIEWKYNRQWAELLAKSGTSLFLSVKPGILNEDEERDVKEF
YRLASLTHTPAEPLDWQNTNCPSKWKMEDGIREYEWYEKSGVSYRTEPETN

Enzyme Prediction     

No EC number prediction in MGYG000002949_02977.

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd14791	GH36	1.59e-37	186	482	2	298	glycosyl hydrolase family 36 (GH36). GH36 enzymes occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-galactosidase, alpha-N-acetylgalactosaminidase, stachyose synthase, and raffinose synthase. All GH36 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH36 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.
cd14792	GH27	7.25e-13	186	325	1	124	glycosyl hydrolase family 27 (GH27). GH27 enzymes occur in eukaryotes, prokaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-N-acetylgalactosaminidase, and 3-alpha-isomalto-dextranase. All GH27 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH27 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.
pfam02065	Melibiase	1.15e-06	191	273	46	124	Melibiase. Glycoside hydrolase families GH27, GH31 and GH36 form the glycoside hydrolase clan GH-D. Glycoside hydrolase family 36 can be split into 11 families, GH36A to GH36K. This family includes enzymes from GH36A-B and GH36D-K and from GH27.
COG3345	GalA	3.59e-06	180	273	286	375	Alpha-galactosidase [Carbohydrate transport and metabolism].
cd14790	GH_D	1.72e-05	193	482	8	253	Glycoside hydrolases, clan D. This group of glycosyl hydrolase families is comprised of glycosyl hydrolase family 31 (GH31), family 36 (GH36), and family 27 (GH27). These structurally and mechanistically related protein families are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively. They have a wide range of functions including alpha-glucosidase, alpha-xylosidase, 6-alpha-glucosyltransferase, 3-alpha-isomaltosyltransferase, alpha-N-acetylgalactosaminidase, stachyose synthase, raffinose synthase, and alpha-1,4-glucan lyase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
SNU96820.1	4.08e-240	5	527	8	533
QIB59833.1	3.81e-234	5	524	8	533
BDA09953.1	2.19e-233	5	524	8	533
CBL19648.1	2.45e-233	8	521	31	544
QCU01578.1	8.08e-232	8	521	31	544

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000047	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002949_02977.