dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: MGYG000002963_02703

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Basic Information help

Species

Anaerosporobacter mobilis

Lineage

Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Anaerosporobacter; Anaerosporobacter mobilis

CAZyme ID

MGYG000002963_02703

CAZy Family

CBM35

CAZyme Description

hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
863	MGYG000002963_18\|CGC3	96740.38	4.3631

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002963	5077023	MAG	United States	North America

Gene Location

Start: 69021; End: 71612 Strand: +

Full Sequence Download help

Enzyme Prediction help

EC	3.2.1.78

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
GH26	178	512	1.6e-92	0.9933993399339934
CBM3	720	800	3.5e-27	0.9772727272727273
CBM35	58	162	8.5e-24	0.8991596638655462
CBM46	627	698	4e-16	0.8735632183908046

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam02156	Glyco_hydro_26	9.17e-46	178	512	2	311	Glycosyl hydrolase family 26.
cd04086	CBM35_mannanase-like	3.15e-32	40	163	2	119	Carbohydrate Binding Module 35 (CBM35); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains. This family includes carbohydrate binding module 35 (CBM35) domains that are appended to several carbohydrate binding enzymes, including periplasmic component of ABC-type sugar transport system involved in carbohydrate transport and metabolism, and several glycoside hydrolase (GH) domains, including GH26. These CBM6s are non-catalytic carbohydrate binding domains that facilitate the strong binding of the GH catalytic modules with their dedicated, insoluble substrates. Examples of proteins having CMB35s belonging to this family are mannanase A from Clostridium thermocellum (GH26), Man26B from Paenibacillus sp. BME-14 (GH26), and the multifunctional Cel44C-Man26A from Paenibacillus polymyxa GS01 (which has two GH domains, GH44 and GH26). GH26 mainly includes mannan endo-1,4-beta-mannosidase which hydrolyzes 1,4-beta-D-linkages in mannans, galacto-mannans, glucomannans, and galactoglucomannans, but displays little activity towards other plant cell wall polysaccharides. A few proteins belonging to this family have additional CBM3 domains; these CBM3s are not found in the CBM6-CBM35-CBM36_like superfamily.
pfam03442	CBM_X2	8.21e-26	620	702	1	83	Carbohydrate binding domain X2. This domain binds to cellulose and to bacterial cell walls. It is found in glycosyl hydrolases and in scaffolding proteins of cellulosomes (multiprotein glycosyl hydrolase complexes). In the cellulosome it may aid cellulose degradation by anchoring the cellulosome to the bacterial cell wall and by binding it to its substrate. This domain has an Ig-like fold.
pfam00942	CBM_3	4.16e-24	718	799	1	82	Cellulose binding domain.
pfam03442	CBM_X2	4.13e-21	527	609	1	83	Carbohydrate binding domain X2. This domain binds to cellulose and to bacterial cell walls. It is found in glycosyl hydrolases and in scaffolding proteins of cellulosomes (multiprotein glycosyl hydrolase complexes). In the cellulosome it may aid cellulose degradation by anchoring the cellulosome to the bacterial cell wall and by binding it to its substrate. This domain has an Ig-like fold.

CAZyme Hits help

Hit ID	Query Start	Query End	Hit Start	Hit End
ABX42494.1	1	863	1	857
ASA20068.1	1	863	1	857
AIQ59300.1	1	863	1	858
ASR49482.1	1	862	1	858
QOS82751.1	1	863	1	857

PDB Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3ZM8_A	3.70e-59	42	513	16	447	ChainA, Gh26 Endo-beta-1,4-mannanase [Podospora anserina S mat+]
3ZQW_A	1.30e-47	715	863	5	153	ChainA, CELLULOSOMAL SCAFFOLDIN [Acetivibrio cellulolyticus],3ZU8_A Chain A, Cellulosomal Scaffoldin [Acetivibrio cellulolyticus],3ZUC_A Chain A, CELLULOSOMAL SCAFFOLDIN [Acetivibrio cellulolyticus]
6D2X_A	2.16e-46	176	513	4	334	Crystalstructure of the GH26 domain from PbGH26-GH5A endo-beta-mannanase/endo-beta-glucanase from Prevotella bryantii [Prevotella bryantii B14]
6D2W_A	2.63e-45	152	513	70	425	Crystalstructure of Prevotella bryantii endo-beta-mannanase/endo-beta-glucanase PbGH26A-GH5A [Prevotella bryantii B14],6D2W_B Crystal structure of Prevotella bryantii endo-beta-mannanase/endo-beta-glucanase PbGH26A-GH5A [Prevotella bryantii B14]
4JO5_A	4.11e-44	714	863	17	172	ChainA, Cellulosome anchoring protein cohesin region [Acetivibrio thermocellus YS]

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P23659	5.31e-91	517	863	642	986	Endoglucanase Z OS=Thermoclostridium stercorarium OX=1510 GN=celZ PE=1 SV=1
P50900	2.88e-68	588	863	646	914	Exoglucanase-2 OS=Thermoclostridium stercorarium (strain ATCC 35414 / DSM 8532 / NCIMB 11754) OX=1121335 GN=celY PE=1 SV=2
Q3MUH7	4.00e-65	613	863	774	1027	Xyloglucanase OS=Paenibacillus sp. OX=58172 GN=xeg74 PE=1 SV=1
G2Q4H7	5.70e-57	35	513	38	476	Mannan endo-1,4-beta-mannosidase OS=Myceliophthora thermophila (strain ATCC 42464 / BCRC 31852 / DSM 1799) OX=573729 GN=Man26A PE=1 SV=1
P55297	3.09e-52	58	520	36	468	Mannan endo-1,4-beta-mannosidase B OS=Piromyces sp. OX=45796 GN=MANB PE=2 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000274	0.998947	0.000216	0.000194	0.000179	0.000157

TMHMM Annotations download full data without filtering help

start	end
7	26