CAZyme Information: MGYG000002980_02013

Basic Information

• Species: UBA1691 sp002320555
• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Acutalibacteraceae; UBA1691; UBA1691 sp002320555
• CAZyme ID: MGYG000002980_02013
• CAZy Family: GH110
• CAZyme Description: Alpha-1,3-galactosidase A

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
834		92213.97	6.403

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002980	2260187	MAG	United States	North America

• Gene Location: Start: 3558; End: 6062 Strand: -

Full Sequence      

MDANHTILRVTDYGADPVGEQDSTQAVQAALEAARNTSGPVTLLFPKGEYHFYKDFAPKR
LYHTSNTDSCSHPEKTIAILIENQEDLTLDGDGSLFLMHGNLMALAVVRSKRIVLRDFSW
DFAVPTVSEMTVTGFGKKGLSHYTDFYIAGAFPFTVSGGRSVLWTGGESLRGTGPYWTQK
NQHNGWSVVGYDPNTGISRRYSILQGPFARARKIERLAPNRMRVTYFGKRPEIQKTGMVY
ELCASKTRETAGAFNWESEDLLIEKVNVHYMHGFGWLTQMCRDVTYRDCRFMPRSGTGKF
TTSFADLIHASGVAGTMTVENCVFGHAHDDPINLHGTFTRVEKRLDARTLMLRYVHKQQG
GFPQFHTGDEVIFYARDTLAPLCGKEETYRVVKAIHPGEGGNSLKTMTVTFDRDLPEEIM
DKIGSEPKYVAENVTFTANVVIRNNFFTTIPTRGILCTQRKKVLIENNVFQNMAMASIFL
SNDSNEWYESGPIRDLTIRGNTFYIRPAGQTEWKYKPAIYIHPEVKGGSSKLSADTPVHR
NLTIEENTFYMGHDGVVRAEGVDGLSFRRNRVLRDAPDIRLHISPETCALKSGERVSLQT
QADGRCNQANEDLLFSFEACSHVTLMENTYDGGLKAGVALVRTPRESVDCRDALSFDADV
PASAPVGTIAYRSTDEAVVSVDDWGQMTAVGPGGAYVYAQTMWNEISVQSNLVPVSVDGA
DLPPAREPESAAHDARVVIPSLVFDTVGSAEKSIVVTTAPDCELGSVEIRLSADETAGAL
TLCTGDERALLARTQERTLSVNATLSPGLNSFYARVTARDGQTVSERAVHIIRI

Enzyme Prediction     

No EC number prediction in MGYG000002980_02013.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH110	8	599	4.2e-148	0.9927007299270073

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam12708	Pectate_lyase_3	8.28e-06	10	50	4	44	Pectate lyase superfamily protein. This family of proteins possesses a beta helical structure like Pectate lyase. This family is most closely related to glycosyl hydrolase family 28.
pfam13229	Beta_helix	1.19e-04	434	504	51	111	Right handed beta helix region. This region contains a parallel beta helix region that shares some similarity with Pectate lyases.
PLN02218	PLN02218	1.30e-04	6	101	66	171	polygalacturonase ADPG
pfam13229	Beta_helix	2.25e-04	438	572	32	134	Right handed beta helix region. This region contains a parallel beta helix region that shares some similarity with Pectate lyases.
pfam13229	Beta_helix	3.22e-04	433	572	4	110	Right handed beta helix region. This region contains a parallel beta helix region that shares some similarity with Pectate lyases.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AYE35188.1	6.24e-251	4	717	42	756
QAS60591.1	8.80e-251	4	717	42	756
ATD55583.1	5.96e-218	8	652	3	611
ATD56740.1	5.96e-218	8	652	3	611
QBJ75880.1	6.39e-218	8	652	5	613

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7JW4_A	9.77e-44	1	549	21	542	Crystalstructure of PdGH110B in complex with D-galactose [Pseudoalteromonas distincta],7JW4_B Crystal structure of PdGH110B in complex with D-galactose [Pseudoalteromonas distincta]
7JWF_A	4.36e-43	1	549	21	542	Crystalstructure of PdGH110B D344N in complex with alpha-(1,3)-galactobiose [Pseudoalteromonas distincta],7JWF_B Crystal structure of PdGH110B D344N in complex with alpha-(1,3)-galactobiose [Pseudoalteromonas distincta],7JWF_C Crystal structure of PdGH110B D344N in complex with alpha-(1,3)-galactobiose [Pseudoalteromonas distincta],7JWF_D Crystal structure of PdGH110B D344N in complex with alpha-(1,3)-galactobiose [Pseudoalteromonas distincta]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
B1V8K7	5.75e-126	6	717	33	723	Alpha-1,3-galactosidase A OS=Streptacidiphilus griseoplanus OX=66896 GN=glaA PE=1 SV=1
Q826C5	4.16e-109	7	638	40	622	Alpha-1,3-galactosidase A OS=Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680) OX=227882 GN=glaA PE=3 SV=1
Q64MU6	6.38e-79	10	574	28	552	Alpha-1,3-galactosidase A OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=glaA PE=3 SV=1
Q5L7M8	3.29e-78	10	574	28	552	Alpha-1,3-galactosidase A OS=Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 / Onslow) OX=272559 GN=glaA PE=3 SV=1
Q8A2Z5	4.95e-75	27	572	31	532	Alpha-1,3-galactosidase A OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=glaA PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000033	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002980_02013.