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CAZyme Information: MGYG000002994_00127

You are here: Home > Sequence: MGYG000002994_00127

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Megasphaera sp002319965
Lineage Bacteria; Firmicutes_C; Negativicutes; Veillonellales; Megasphaeraceae; Megasphaera; Megasphaera sp002319965
CAZyme ID MGYG000002994_00127
CAZy Family GT83
CAZyme Description Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
519 MGYG000002994_1|CGC2 59048.91 9.4721
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002994 2223689 MAG United States North America
Gene Location Start: 135029;  End: 136588  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000002994_00127.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT83 5 420 3.4e-108 0.8055555555555556

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG1807 ArnT 4.52e-59 2 449 1 464
4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis].
PRK13279 arnT 1.53e-41 12 326 10 332
lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase.
pfam13231 PMT_2 7.36e-19 64 215 1 157
Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.
pfam02366 PMT 9.04e-14 39 223 35 240
Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AVO73979.1 2.90e-308 1 519 1 519
CCC72524.1 2.90e-308 1 519 1 519
AVO26796.1 4.12e-308 1 519 1 519
ALG41392.1 5.85e-308 1 519 1 519
AXL21031.1 1.97e-245 1 519 1 519

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5EZM_A 4.53e-37 4 414 27 457
CrystalStructure of ArnT from Cupriavidus metallidurans in the apo state [Cupriavidus metallidurans CH34],5F15_A Crystal Structure of ArnT from Cupriavidus metallidurans bound to Undecaprenyl phosphate [Cupriavidus metallidurans CH34]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
C5BDQ8 3.09e-35 17 326 10 331
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Edwardsiella ictaluri (strain 93-146) OX=634503 GN=arnT PE=3 SV=1
A0KGY4 2.55e-34 22 324 17 327
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049) OX=380703 GN=arnT PE=3 SV=1
B2VBI7 1.26e-33 8 324 4 329
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99) OX=465817 GN=arnT PE=3 SV=1
A8GDR9 3.24e-33 8 326 6 333
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Serratia proteamaculans (strain 568) OX=399741 GN=arnT PE=3 SV=1
B4ETL9 4.32e-33 31 326 31 335
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2 OS=Proteus mirabilis (strain HI4320) OX=529507 GN=arnT2 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000039 0.000002 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      download full data without filtering help

start end
12 31
85 107
114 136
158 189
201 220
251 273
286 303
308 327
340 359
369 388
395 417