CAZyme Information: MGYG000003002_00944

Basic Information

• Species: Streptococcus sanguinis_H
• Lineage: Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus sanguinis_H
• CAZyme ID: MGYG000003002_00944
• CAZy Family: GH3
• CAZyme Description: Beta-hexosaminidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
929	MGYG000003002_34|CGC1	99605.02	4.7957

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003002	1839775	MAG	United States	North America

• Gene Location: Start: 11147; End: 13936 Strand: -

Full Sequence      

MKRYKLLLALALSLLVFWPMGAIKADTVNQPPESANQSEQASAAVVTNSSDSSAGARGTP
SQDSQIAEKALSVSDVPSVAATETTASTKEGNTGNLVEDSAKPATAQPAEVLSAANQTQD
QAASDAPSASKRVRELVEDMTLRQKITQMLMPDFRKWQQEGQAAQSDMTELNKEVAEAVD
KYDFGGVILFAENVKGTAQTLALTQALQQAAISNQANNGKLPLLLAIDQEGGIVYRLGSG
TALPGNMAVGATRDPELANQAGQIIGRELSALGLNVNFAPVFDTNNNPQNPVIGLRSFSS
DPKVVARLGTAMMEGIQKYNVAVAAKHFPGHGDTAVDSHTGLPLVDKSYAELEALELLPF
KAAIDKNADMLMTAHIQYPQIEKDTVISKQTGETIYIPATLSDDIITGIVRKKFGYKGVV
VSDAMGMDAIAKNFGESEAAIMAIKSGVDVVLMPTVLRSKSDLAKIDKIINDIEQAVQRG
DIPVSRLDESVTRILNLKEKRGILDFDPSERAQAKAEATVGSELNRDTERKIAASAVTVV
KNDDTVLPFKVKSGDRILLLAAYDDEVPGLELGVKRLIADGVIPAGVTYEALNYSKTTKL
EDLKGKIDQATHLVLISEIGRQSQLASDFWLTRVPTEVVDYANETGKQAAIMSISKPYDV
ANYPNAKAIVAVYGNKGMDPTESLKPDNAFGPNIPAGVEVIFNGQNHVGRLPVNVPLIKD
GIMSETEVAYPIGHGLFYTDPVKDIKVNIPSSAQLDQPFTATVTLSGLNGLEKNDYRLAL
KMDTQHFSILPSQDYTISGDTVLISKKANDTNPVEISLKGLVEGQFSPVLSLTLIDSQDR
EFSMGEGYYKELVQIAAAGQNTIPGQQTPPQLSLSSVAPVSSRRQLSQQVAQFNQLPKTG
DSSGLFLVSLGALFLFGAVYLYDLSSRRL

Enzyme Prediction     

EC	3.2.1.52

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH3	217	453	2.7e-67	0.9768518518518519

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG1472	BglX	2.25e-103	140	569	1	369	Periplasmic beta-glucosidase and related glycosidases [Carbohydrate transport and metabolism].
pfam00933	Glyco_hydro_3	2.32e-98	141	497	1	316	Glycosyl hydrolase family 3 N terminal domain.
PRK05337	PRK05337	1.50e-53	185	453	27	279	beta-hexosaminidase; Provisional
PRK15098	PRK15098	1.33e-24	118	554	20	411	beta-glucosidase BglX.
pfam01915	Glyco_hydro_3_C	0.007	537	738	1	216	Glycosyl hydrolase family 3 C-terminal domain. This domain is involved in catalysis and may be involved in binding beta-glucan. This domain is found associated with pfam00933.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
SQF71406.1	0.0	1	929	1	929
SQF34679.1	0.0	1	929	1	929
SQG30206.1	0.0	1	929	1	929
QKQ43942.1	0.0	1	929	4	932
ABN44479.1	0.0	1	929	2	930

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3BMX_A	1.59e-168	128	736	27	634	Beta-N-hexosaminidase(YbbD) from Bacillus subtilis [Bacillus subtilis],3BMX_B Beta-N-hexosaminidase (YbbD) from Bacillus subtilis [Bacillus subtilis],3NVD_A Structure of YBBD in complex with pugnac [Bacillus subtilis],3NVD_B Structure of YBBD in complex with pugnac [Bacillus subtilis]
3LK6_A	3.84e-168	128	736	1	608	ChainA, Lipoprotein ybbD [Bacillus subtilis],3LK6_B Chain B, Lipoprotein ybbD [Bacillus subtilis],3LK6_C Chain C, Lipoprotein ybbD [Bacillus subtilis],3LK6_D Chain D, Lipoprotein ybbD [Bacillus subtilis]
4GYJ_A	1.08e-167	128	736	31	638	Crystalstructure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1) [Bacillus subtilis subsp. subtilis str. 168],4GYJ_B Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1) [Bacillus subtilis subsp. subtilis str. 168],4GYK_A Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1211) [Bacillus subtilis subsp. subtilis str. 168],4GYK_B Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1211) [Bacillus subtilis subsp. subtilis str. 168]
6K5J_A	1.39e-82	140	675	11	505	Structureof a glycoside hydrolase family 3 beta-N-acetylglucosaminidase from Paenibacillus sp. str. FPU-7 [Paenibacillaceae]
4ZM6_A	5.72e-81	139	726	6	538	Aunique GCN5-related glucosamine N-acetyltransferase region exist in the fungal multi-domain GH3 beta-N-acetylglucosaminidase [Rhizomucor miehei CAU432],4ZM6_B A unique GCN5-related glucosamine N-acetyltransferase region exist in the fungal multi-domain GH3 beta-N-acetylglucosaminidase [Rhizomucor miehei CAU432]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P40406	8.73e-168	128	736	27	634	Beta-hexosaminidase OS=Bacillus subtilis (strain 168) OX=224308 GN=nagZ PE=1 SV=1
P48823	3.71e-94	140	715	16	596	Beta-hexosaminidase A OS=Pseudoalteromonas piscicida OX=43662 GN=cht60 PE=1 SV=1
Q7WUL3	2.77e-43	196	675	58	529	Beta-N-acetylglucosaminidase/beta-glucosidase OS=Cellulomonas fimi OX=1708 GN=nag3 PE=1 SV=1
Q82SJ8	1.97e-39	185	453	29	282	Beta-hexosaminidase OS=Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298) OX=228410 GN=nagZ PE=3 SV=1
Q0AF74	3.63e-39	185	453	29	282	Beta-hexosaminidase OS=Nitrosomonas eutropha (strain DSM 101675 / C91 / Nm57) OX=335283 GN=nagZ PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000430	0.998779	0.000273	0.000178	0.000166	0.000148

TMHMM  Annotations     

start	end
903	922