Species | CAG-196 sp002102975 | |||||||||||
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Lineage | Bacteria; Cyanobacteria; Vampirovibrionia; Gastranaerophilales; Gastranaerophilaceae; CAG-196; CAG-196 sp002102975 | |||||||||||
CAZyme ID | MGYG000003077_00336 | |||||||||||
CAZy Family | GH23 | |||||||||||
CAZyme Description | Membrane-bound lytic murein transglycosylase F | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location | Start: 346671; End: 347219 Strand: - |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
cd00254 | LT-like | 3.44e-54 | 72 | 176 | 2 | 111 | lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
cd13401 | Slt70-like | 2.87e-51 | 59 | 175 | 9 | 146 | 70kDa soluble lytic transglycosylase (Slt70) and similar proteins. Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda. |
cd16896 | LT_Slt70-like | 9.89e-47 | 57 | 177 | 5 | 146 | uncharacterized lytic transglycosylase subfamily with similarity to Slt70. Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
cd13403 | MLTF-like | 4.66e-43 | 60 | 179 | 1 | 160 | membrane-bound lytic murein transglycosylase F (MLTF) and similar proteins. This subfamily includes membrane-bound lytic murein transglycosylase F (MltF, murein lyase F) that degrades murein glycan strands. It is responsible for catalyzing the release of 1,6-anhydromuropeptides from peptidoglycan. Lytic transglycosylase catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc) as do goose-type lysozymes. However, in addition, it also makes a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
pfam01464 | SLT | 2.82e-37 | 60 | 167 | 1 | 114 | Transglycosylase SLT domain. This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
ART75824.1 | 3.43e-49 | 37 | 176 | 71 | 214 |
QDP40816.1 | 1.38e-48 | 55 | 174 | 92 | 211 |
ASZ63588.1 | 1.41e-48 | 40 | 175 | 44 | 179 |
AWM19240.1 | 2.00e-48 | 56 | 175 | 60 | 179 |
QAW35488.1 | 2.67e-48 | 40 | 175 | 44 | 179 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
5MPQ_A | 1.89e-16 | 54 | 174 | 414 | 551 | BulgecinA: The key to a broad-spectrum inhibitor that targets lytic transglycosylases [Neisseria meningitidis] |
5O1J_A | 1.89e-16 | 54 | 174 | 418 | 555 | Lytictransglycosylase in action [Neisseria meningitidis MC58] |
5O29_A | 1.90e-16 | 54 | 174 | 434 | 571 | Lytictransglycosylase in action [Neisseria meningitidis] |
5O24_A | 1.90e-16 | 54 | 174 | 428 | 565 | Lytictransglycosylase in action [Neisseria meningitidis] |
6FPN_B | 1.90e-16 | 54 | 174 | 424 | 561 | Lytictransglycosylase in action [Neisseria meningitidis MC58] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
O31608 | 3.24e-48 | 37 | 175 | 40 | 179 | Putative murein lytic transglycosylase YjbJ OS=Bacillus subtilis (strain 168) OX=224308 GN=yjbJ PE=3 SV=1 |
O31976 | 1.49e-38 | 37 | 177 | 1400 | 1543 | SPbeta prophage-derived uncharacterized transglycosylase YomI OS=Bacillus subtilis (strain 168) OX=224308 GN=yomI PE=3 SV=2 |
O64046 | 1.49e-38 | 37 | 177 | 1400 | 1543 | Probable tape measure protein OS=Bacillus phage SPbeta OX=66797 GN=yomI PE=3 SV=1 |
A8ZWR8 | 8.76e-18 | 59 | 153 | 289 | 389 | Membrane-bound lytic murein transglycosylase F OS=Desulfococcus oleovorans (strain DSM 6200 / JCM 39069 / Hxd3) OX=96561 GN=mltF PE=3 SV=2 |
P27380 | 1.02e-17 | 69 | 150 | 20 | 100 | Transglycosylase OS=Enterobacteria phage PRD1 OX=10658 GN=VII PE=1 SV=3 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
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1.000054 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |
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