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CAZyme Information: MGYG000003087_01852
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Merdibacter sp900543035 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes; Bacilli; Erysipelotrichales; Erysipelotrichaceae; Merdibacter; Merdibacter sp900543035 | |||||||||||
| CAZyme ID | MGYG000003087_01852 | |||||||||||
| CAZy Family | CBM32 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 2373; End: 7214 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH84 | 333 | 653 | 1.5e-75 | 0.9864406779661017 |
| CBM32 | 51 | 171 | 6.5e-22 | 0.9112903225806451 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam07555 | NAGidase | 3.73e-99 | 333 | 653 | 1 | 292 | beta-N-acetylglucosaminidase. This family has previously been described as a hyaluronidase. However, more recently it has been shown that this family has beta-N-acetylglucosaminidase activity. |
| pfam00754 | F5_F8_type_C | 6.68e-18 | 46 | 170 | 1 | 127 | F5/8 type C domain. This domain is also known as the discoidin (DS) domain family. |
| pfam02838 | Glyco_hydro_20b | 5.52e-14 | 185 | 326 | 1 | 123 | Glycosyl hydrolase family 20, domain 2. This domain has a zincin-like fold. |
| pfam00754 | F5_F8_type_C | 4.34e-10 | 928 | 1050 | 4 | 112 | F5/8 type C domain. This domain is also known as the discoidin (DS) domain family. |
| pfam07554 | FIVAR | 6.31e-08 | 1162 | 1223 | 1 | 69 | FIVAR domain. This domain is found in a wide variety of contexts, but mostly occurring in cell wall associated proteins. A lack of conserved catalytic residues suggests that it is a binding domain. From context, possible substrates are hyaluronate or fibronectin (personal obs: C Yeats). This is further evidenced by. Possibly the exact substrate is N-acetyl glucosamine. Finding it in the same protein as pfam05089 further supports this proposal. It is found in the C-terminal part of Bacillus sp. Gellan lyase, which is removed during maturation. Some of the proteins it is found in are involved in methicillin resistance. The name FIVAR derives from Found In Various Architectures. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| BCI64753.1 | 3.43e-126 | 185 | 809 | 22 | 657 |
| AHF13697.1 | 4.89e-123 | 186 | 805 | 25 | 654 |
| QUT77745.1 | 2.05e-118 | 186 | 968 | 21 | 822 |
| AHF13792.1 | 2.85e-116 | 185 | 805 | 8 | 641 |
| QFQ11845.1 | 2.06e-88 | 185 | 797 | 23 | 648 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6PWI_A | 5.74e-73 | 179 | 771 | 26 | 601 | Structureof CpGH84D [Clostridium perfringens ATCC 13124],6PWI_B Structure of CpGH84D [Clostridium perfringens ATCC 13124] |
| 6PV4_A | 2.29e-67 | 186 | 703 | 32 | 551 | Structureof CpGH84A [Clostridium perfringens ATCC 13124],6PV4_B Structure of CpGH84A [Clostridium perfringens ATCC 13124],6PV4_C Structure of CpGH84A [Clostridium perfringens ATCC 13124],6PV4_D Structure of CpGH84A [Clostridium perfringens ATCC 13124] |
| 6PV5_A | 1.26e-49 | 183 | 633 | 37 | 468 | Structureof CpGH84B [Clostridium perfringens ATCC 13124] |
| 5MI4_A | 1.76e-49 | 289 | 650 | 100 | 431 | BtGH84mutant with covalent modification by MA3 [Bacteroides thetaiotaomicron VPI-5482],5MI5_A BtGH84 mutant with covalent modification by MA3 in complex with PUGNAc [Bacteroides thetaiotaomicron VPI-5482],5MI6_A BtGH84 mutant with covalent modification by MA3 in complex with Thiamet G [Bacteroides thetaiotaomicron VPI-5482],5MI7_A BtGH84 mutant with covalent modification by MA4 in complex with PUGNAc [Bacteroides thetaiotaomicron VPI-5482] |
| 2J4G_A | 2.03e-49 | 289 | 642 | 88 | 411 | Bacteroidesthetaiotaomicron GH84 O-GlcNAcase in complex with n-butyl- thiazoline inhibitor [Bacteroides thetaiotaomicron VPI-5482],2J4G_B Bacteroides thetaiotaomicron GH84 O-GlcNAcase in complex with n-butyl- thiazoline inhibitor [Bacteroides thetaiotaomicron VPI-5482] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P26831 | 1.38e-64 | 186 | 703 | 39 | 558 | Hyaluronoglucosaminidase OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagH PE=1 SV=2 |
| Q89ZI2 | 1.46e-48 | 289 | 642 | 110 | 433 | O-GlcNAcase BT_4395 OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_4395 PE=1 SV=1 |
| Q0TR53 | 8.08e-40 | 271 | 699 | 123 | 516 | O-GlcNAcase NagJ OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) OX=195103 GN=nagJ PE=1 SV=1 |
| Q8XL08 | 2.44e-39 | 271 | 699 | 123 | 516 | O-GlcNAcase NagJ OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagJ PE=1 SV=1 |
| Q8VIJ5 | 3.17e-16 | 334 | 622 | 63 | 331 | Protein O-GlcNAcase OS=Rattus norvegicus OX=10116 GN=Oga PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.007230 | 0.989529 | 0.002462 | 0.000281 | 0.000237 | 0.000255 |
