CAZyme Information: MGYG000003135_01568

Basic Information

• Species: Cutibacterium granulosum
• Lineage: Bacteria; Actinobacteriota; Actinomycetia; Propionibacteriales; Propionibacteriaceae; Cutibacterium; Cutibacterium granulosum
• CAZyme ID: MGYG000003135_01568
• CAZy Family: CBM5
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
990		101481.05	4.466

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003135	2072889	MAG	United States	North America

• Gene Location: Start: 16485; End: 19457 Strand: -

Full Sequence      

MNTSGHVRRVLTGIAAVTTSALACAGLLVPSANAGPAPHPLINEVYGGGGNSGATLTHDF
VELVNPTSETISLDGYVVEYYGATGNRGNRCTLSGSVAPGGHFLVQQAKGAGGTQALPTP
DATCGANMSGTKGSVQLVGSDGTVVDLVGYGAATKAEGKPTKALSNTTSAQRRGLEDTDD
NSADFVIGTPSPMNSASTPAPSTPGTPDPTVSPTSSASAVASPTAPETPAGQTSIADIQG
TTDISPMVGRTVTTTGVITAAYPKGGFNGLYIQTPGSGGVAKTPTDASDGIFVHSAKAAS
AYTAGQCVVVSGEVSEFNGLTEINGTSVTETKGCADVKPVKLAALPRTDAQREAYESMLV
EPQGTYTISNNYQLNQFGTVGLAFGTEPLYQGTEVARPGEDAKKVEDENRARSINLDDGA
SWNYQTNDEAKNSPLPYLSQDTPMRTGSHVGFTKPVIMDYRFGWNLQPTGMVSGAQSPHS
PITTTNDRPAKAPSFDSDLKLASFNVLNYFTDLGKDEDGCKAYTDRTGTPVTANFCTVRG
AYTQEAFHDQQAKIVTAINGLDADVVALMEVENSASITYLPGQPRDKALAHLVDELNKAA
GSQVWGYVASPTVVPPHEDVIRTAFIYRLDSVRPEGPSLILMDDAYANARQPLAQKFVAK
DARGSFVAVANHFKSKGSGEDDGTGQGKSNPSRIAQAQALLDWSAKEFAGEPVFLLGDFN
AYGMEDPVMKIKDAGYTEVVEQLAPGASTFQYGGRLGSLDHIFANAAAVRMVHGAGVWDI
NADESIAMQYSRRNYNVTDFHTSGPWAASDHDPALVGITFPGASTPQPSGTPSVEPSASV
SSQPSGEPSVSPTASSVTPSVTPGGPSVTPAPSVSTPSASPSLPALPTPDPGDEPSVLPV
PTVTPESTVTLGPAMSSEPTVSPEPTRPATPGDESSATAGGTPGTPSATPAGASPSAHGT
GIDDVSGDAAQAAVVPGGSAELPALPATGI

Enzyme Prediction     

No EC number prediction in MGYG000003135_01568.

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
NF033681	ExeM_NucH_DNase	0.0	254	820	1	545	ExeM/NucH family extracellular endonuclease.
COG2374	COG2374	1.92e-156	13	824	4	792	Predicted extracellular nuclease [General function prediction only].
NF033680	exonuc_ExeM-GG	5.74e-61	13	837	3	861	extracellular exonuclease ExeM. ExeM, as described in Shewanella oneidensis, is a biofilm formation-associated exonuclease that cleaves extracellular DNA (eDNA), a biofilm component. Members of the ExeM family contain two or three pairs of Cys residues, presumed to form disulfide bonds, and a C-terminal GlyGly-CTERM membrane-anchoring segment. Strangely, engineered removal of the GlyGly-CTERM region did not result in net export from the cell and appearance of the enzyme in culture supernatants.
cd10283	MnuA_DNase1-like	9.73e-58	499	818	1	266	Mycoplasma pulmonis MnuA nuclease-like. This subfamily includes Mycoplasma pulmonis MnuA, a membrane-associated nuclease related to Deoxyribonuclease 1 (DNase1 or DNase I, EC 3.1.21.1). The in vivo role of MnuA is as yet undetermined. This subfamily belongs to the large EEP (exonuclease/endonuclease/phosphatase) superfamily that contains functionally diverse enzymes that share a common catalytic mechanism of cleaving phosphodiester bonds.
cd04486	YhcR_OBF_like	1.96e-16	253	330	1	73	YhcR_OBF_like: A subfamily of OB-fold domains similar to the OB folds of Bacillus subtilis YhcR. YhcR is a sugar-nonspecific nuclease, which is active in the presence of Ca2+ and Mn2+. It cleaves RNA endonucleolytically, producing 3'-monophosphate nucleosides. YhcR appears to be the major Ca2+ activated nuclease of B. subtilis. YhcR may be localized in the cell wall.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QAY59561.1	6.31e-195	41	822	35	930
ACZ32093.1	2.45e-186	8	819	6	829
QAY71724.1	8.68e-185	35	819	35	839
ANC31565.1	6.51e-184	17	818	24	837
QAY64865.1	8.82e-183	14	828	21	855

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.001233	0.575438	0.420430	0.002213	0.000425	0.000228

TMHMM  Annotations     

start	end
7	29