CAZyme Information: MGYG000003135_01726

Basic Information

• Species: Cutibacterium granulosum
• Lineage: Bacteria; Actinobacteriota; Actinomycetia; Propionibacteriales; Propionibacteriaceae; Cutibacterium; Cutibacterium granulosum
• CAZyme ID: MGYG000003135_01726
• CAZy Family: GH77
• CAZyme Description: 4-alpha-glucanotransferase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
716		79505.16	5.1707

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003135	2072889	MAG	United States	North America

• Gene Location: Start: 16543; End: 18693 Strand: +

Full Sequence      

MALSDPALGELADRFGISTQFYDWKGRHTQVGEQTVIAILAEFGVDASTPERARAAAQRV
RDDHWRRIVQPCVVLRAGQEGRVDVHVPAGAPVSLRIVGEDGNDHLPWQVDNWNPDRPID
GQMIGEATFGIPSNLPLGYHELIVTIGTHDAEGSAADGGIHTTATSTIIVTPNRVGLPRR
MGASRVWGYAAQLYSVRSHHSWGLGDLTDLADLCTWSASQGAGYLLTNPLHAAEVAGRME
PSPYLPSSRLFVNPIYIRPELIAEYHDLDQYDASLVESLRTTTLDDDPQALLDRDRTWQA
KSQALELIHRVDMSASRRMAFTAFRVARGRRLEDFATWCLLSELHGSDWHDWPAELHDPH
GAAVARVRREHADRIDFHMWLQWIADQQLSTAQSSGTDAGMPVGLICDLAVGVNGSGADA
WMLNGLFAREMNVGAPPDPFNQAGQDWGQPPMRPDVLEQMAYAPLREMVSSALRHAGGVR
IDHIMGLFRLWWVPKGLDPRHGAYVRYNHEAMVGVVALEAYRAGALVIGEDLGTVEPWVR
DHLASRGILGTSIMWFETGPDGRPKQPQQWREHAMSSVTSHDLPPTSSYLRGDHVELRDR
LGLLTESVDEERENARRERETWLASLRQQGVLEADEDDPEQVTLAMHTLLTRTPSKVINA
TLTDAVGDPRTQNLPGTEDEYPNWRVPLSGPDGEPVYLEDLYSSDRVARMSKVLRG

Enzyme Prediction     

EC	2.4.1.25

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH77	192	691	2.6e-143	0.9493927125506073

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
PRK14507	PRK14507	1.04e-159	1	716	1	719	malto-oligosyltrehalose synthase.
pfam02446	Glyco_hydro_77	4.99e-150	192	689	2	458	4-alpha-glucanotransferase. These enzymes EC:2.4.1.25 transfer a segment of a (1,4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1,4)-alpha-D-glucan.
COG1640	MalQ	3.03e-149	182	702	9	506	4-alpha-glucanotransferase [Carbohydrate transport and metabolism].
PRK11052	malQ	9.20e-135	7	712	5	683	4-alpha-glucanotransferase; Provisional
PRK14510	PRK14510	4.55e-110	185	691	723	1197	bifunctional glycogen debranching protein GlgX/4-alpha-glucanotransferase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
SNV38908.1	0.0	1	716	1	716
AFV90170.1	0.0	1	716	1	704
AMS04941.1	0.0	1	716	1	704
AOZ46425.1	0.0	1	716	1	704
AZP37531.1	0.0	1	716	1	704

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5B68_A	2.99e-171	8	712	7	704	Crystalstructure of apo amylomaltase from Corynebacterium glutamicum [Corynebacterium glutamicum],5JJH_A Crystal structure of amylomaltase from Corynebacterium glutamicum [Corynebacterium glutamicum]
4S3P_A	1.17e-82	101	714	71	683	AmylomaltaseMalQ from Escherichia coli, apo structure [Escherichia coli K-12],4S3P_B Amylomaltase MalQ from Escherichia coli, apo structure [Escherichia coli K-12],4S3Q_A Amylomaltase MalQ from Escherichia coli in complex with maltose [Escherichia coli K-12],4S3Q_B Amylomaltase MalQ from Escherichia coli in complex with maltose [Escherichia coli K-12],4S3Q_C Amylomaltase MalQ from Escherichia coli in complex with maltose [Escherichia coli K-12]
4S3R_A	1.21e-77	101	714	71	683	AmylomaltaseMalQ from Escherichia coli in complex with the pseudo-heptasaccharide acarviosine-glucose-acarbose [Escherichia coli K-12]
2X1I_A	7.46e-18	321	591	127	404	glycosidehydrolase family 77 4-alpha-glucanotransferase from thermus brockianus [Thermus brockianus]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P65337	4.98e-266	6	716	6	715	4-alpha-glucanotransferase OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) OX=233413 GN=malQ PE=3 SV=1
P9WK22	4.98e-266	6	716	6	715	4-alpha-glucanotransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=malQ PE=3 SV=1
P9WK23	4.98e-266	6	716	6	715	4-alpha-glucanotransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=malQ PE=1 SV=1
P15977	6.14e-82	101	714	71	683	4-alpha-glucanotransferase OS=Escherichia coli (strain K12) OX=83333 GN=malQ PE=1 SV=2
P45176	1.36e-77	135	691	110	676	4-alpha-glucanotransferase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=malQ PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000048	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003135_01726.