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CAZyme Information: MGYG000003177_00037
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Amulumruptor sp900539915 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae; Amulumruptor; Amulumruptor sp900539915 | |||||||||||
| CAZyme ID | MGYG000003177_00037 | |||||||||||
| CAZy Family | GT2 | |||||||||||
| CAZyme Description | Tyrocidine synthase 3 | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 36365; End: 43642 Strand: + | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| PRK12316 | PRK12316 | 0.0 | 3 | 2015 | 1558 | 3624 | peptide synthase; Provisional |
| PRK05691 | PRK05691 | 0.0 | 37 | 2033 | 711 | 2797 | peptide synthase; Validated |
| PRK12467 | PRK12467 | 0.0 | 20 | 2040 | 68 | 2193 | peptide synthase; Provisional |
| cd05930 | A_NRPS | 4.56e-160 | 452 | 914 | 2 | 444 | The adenylation domain of nonribosomal peptide synthetases (NRPS). The adenylation (A) domain of NRPS recognizes a specific amino acid or hydroxy acid and activates it as an (amino) acyl adenylate by hydrolysis of ATP. The activated acyl moiety then forms a thioester bond to the enzyme-bound cofactor phosphopantetheine of a peptidyl carrier protein domain. NRPSs are large multifunctional enzymes which synthesize many therapeutically useful peptides in bacteria and fungi via a template-directed, nucleic acid independent nonribosomal mechanism. These natural products include antibiotics, immunosuppressants, plant and animal toxins, and enzyme inhibitors. NRPS has a distinct modular structure in which each module is responsible for the recognition, activation, and in some cases, modification of a single amino acid residue of the final peptide product. The modules can be subdivided into domains that catalyze specific biochemical reactions. |
| PRK12467 | PRK12467 | 1.08e-150 | 1019 | 2029 | 51 | 1105 | peptide synthase; Provisional |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QND46664.1 | 5.97e-203 | 239 | 2014 | 805 | 2663 |
| ACX49739.1 | 9.66e-126 | 3 | 1714 | 11 | 1837 |
| BAY30132.1 | 9.57e-93 | 20 | 1000 | 2265 | 3297 |
| BAZ00088.1 | 1.25e-92 | 4 | 1000 | 2247 | 3295 |
| BAZ75991.1 | 1.25e-92 | 4 | 1000 | 2247 | 3295 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6MFZ_A | 1.06e-227 | 436 | 2001 | 204 | 1785 | Crystalstructure of dimodular LgrA in a condensation state [Brevibacillus parabrevis],6MFZ_B Crystal structure of dimodular LgrA in a condensation state [Brevibacillus parabrevis] |
| 6MFY_A | 2.26e-215 | 436 | 1934 | 204 | 1716 | Crystalstructure of a 5-domain construct of LgrA in the substrate donation state [Brevibacillus parabrevis],6MG0_A Crystal structure of a 5-domain construct of LgrA in the thiolation state [Brevibacillus parabrevis],6MG0_B Crystal structure of a 5-domain construct of LgrA in the thiolation state [Brevibacillus parabrevis] |
| 6MFW_A | 8.13e-134 | 436 | 1396 | 204 | 1168 | Crystalstructure of a 4-domain construct of LgrA in the substrate donation state [Brevibacillus parabrevis] |
| 6MFX_A | 2.00e-133 | 436 | 1396 | 204 | 1168 | Crystalstructure of a 4-domain construct of a mutant of LgrA in the substrate donation state [Brevibacillus parabrevis] |
| 5ES5_A | 3.52e-112 | 436 | 993 | 202 | 760 | Crystalstructure of the initiation module of LgrA in the 'open' and 'closed ' adenylation states [Brevibacillus parabrevis],5ES5_B Crystal structure of the initiation module of LgrA in the 'open' and 'closed ' adenylation states [Brevibacillus parabrevis],5ES8_A Crystal structure of the initiation module of LgrA in the thiolation state [Brevibacillus parabrevis],5ES8_B Crystal structure of the initiation module of LgrA in the thiolation state [Brevibacillus parabrevis],5ES9_A Crystal structure of the LgrA initiation module in the formylation state [Brevibacillus parabrevis],5ES9_B Crystal structure of the LgrA initiation module in the formylation state [Brevibacillus parabrevis] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| O68006 | 4.51e-250 | 3 | 2001 | 1673 | 3717 | Bacitracin synthase 1 OS=Bacillus licheniformis OX=1402 GN=bacA PE=3 SV=1 |
| P0C064 | 3.59e-236 | 3 | 2026 | 1063 | 3135 | Gramicidin S synthase 2 OS=Brevibacillus brevis OX=1393 GN=grsB PE=1 SV=2 |
| P0C063 | 9.19e-235 | 3 | 2026 | 1063 | 3136 | Gramicidin S synthase 2 OS=Aneurinibacillus migulanus OX=47500 GN=grsB PE=3 SV=2 |
| O68007 | 2.03e-232 | 3 | 2002 | 77 | 2118 | Bacitracin synthase 2 OS=Bacillus licheniformis OX=1402 GN=bacB PE=3 SV=1 |
| O30408 | 2.03e-228 | 3 | 2001 | 1064 | 3098 | Tyrocidine synthase 2 OS=Brevibacillus parabrevis OX=54914 GN=tycB PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000067 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |