CAZyme Information: MGYG000003192_02648

Basic Information

• Species: UBA5416 sp900539175
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; UBA5416; UBA5416 sp900539175
• CAZyme ID: MGYG000003192_02648
• CAZy Family: GH115
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1130	MGYG000003192_69|CGC1	130892.22	5.1693

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003192	4033193	MAG	United States	North America

• Gene Location: Start: 16309; End: 19701 Strand: -

Full Sequence      

MAGIAMETGTFVTIGVSQMESPAVRIAAQNLKQDLMSVLAAEVSLEENKGNETIIVGTIG
VSQGIEQYFDPGKLQDELGNFRKEAYIHAVSDGKLVIAGTDRRGTIYGIYDFCEWIGVSP
WYYWADVPIRKKERIQIPEDYEKIDFPSVEYRGIFINDEEELDHWARLHMNEDTIGVHTY
EKIFELLLRLKGNYIWPAMHVNSFNRKQENGALAERMGIVVGTSHCDMLMRSNNREWRPW
LEQKGYQDVRYDYSVTGKNREILHEYWRESVRQNKEFEVSYTLGMRGIHDSGFETSMLTG
NTEEELRQQKIRLLETVIENQNKILEEELDEVPLKLFIPYKEVLELYDEGLCVPEEFTII
WSNDNYGYIRRYPSEKERKRQGGHGIYYHNSYWSPPGRSYLFLCSTPLAHTKYELMKAYH
EGIQKLWILNVGALKPLEMETEFFLRLAWEAGKEEGRTRNVDDYVSQWLGRNFTGAEEKM
LGPLLNQFSQIANVRKLEMMEDDVFSQTAYGDEGAVRLHKLREIVRKADGIYRGLPEEEK
DAFFQMVLLRIHAVWLTMCQYYFSDRSTLCHSQGKMQAAALYVKETREYEDARRKLIFYY
NQVVSGGKWNGIVTPEDFPPPRTAMYPACTPPLQIGERKMLVHLWNEEERLSFRKPGIKW
LEISNGGEGWFDFHAEAPEWVELSESRGRIYSEKRIMVTVKEIREGAEGEIRLWNETDKV
LQCVPIEILPFGRSGGTEEDGAVVIPMQGVEAEGFRTIHRLGREEGDLLEGYTKGAEVSF
PVFFESDGKFLLEIHRFPSLNSTGRIRVGIQMDHGEVQIVESQAKDEWKSTWSRNTMDNV
DRLYLTLPWMERGHHCLSVKVIDRYFAFSRMVIYTKQRKENNLGIIQGNQELPQTGMVRE
WAERFYGISDLGPRKEIFADAKTRKDSLTPTDQFVESERYAETKKPEEILKAADSVFCEN
ENTVKIDAVTAYMQTQYAYTTNGNWQYCSSESYGRSGLAMYLRQRGRTWERAGEAPALNY
EIECGDGSYTLWILMRIDHADPSCMAVAVDGMFVEKDLLYHEGKTWRYEAEQVWRWIPFA
RLSLSGGRHLLTVAVMASGIRIDRLYLSDRNNRPPVDLYWNAAGSQGCAD

Enzyme Prediction     

EC	3.2.1.-

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH115	7	865	2e-187	0.9799139167862266

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam15979	Glyco_hydro_115	1.01e-132	147	499	3	334	Glycosyl hydrolase family 115. Glyco_hydro_115 is a family of glycoside hydrolases likely to have the activity of xylan a-1,2-glucuronidase, EC:3.2.1.131, or a-(4-O-methyl)-glucuronidase EC:3.2.1.-.
pfam17829	GH115_C	4.27e-14	738	884	4	169	Gylcosyl hydrolase family 115 C-terminal domain. This domain is found at the C-terminus of glycosyl hydrolase family 115 proteins. This domain has a beta-sandwich fold.
pfam03648	Glyco_hydro_67N	0.003	20	111	29	119	Glycosyl hydrolase family 67 N-terminus. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the N-terminal region of alpha-glucuronidase. The N-terminal domain forms a two-layer sandwich, each layer being formed by a beta sheet of five strands. A further two helices form part of the interface with the central, catalytic, module (pfam07488).

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QOV19968.1	0.0	12	1121	12	1121
AJE49570.1	0.0	12	1120	20	1207
QOH62055.1	0.0	12	1120	20	1207
ADO56562.1	0.0	12	1120	20	1207
CCC85271.1	0.0	12	1120	20	1207

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5BY3_A	2.34e-95	6	649	22	651	Anovel family GH115 4-O-Methyl-alpha-glucuronidase, BtGH115A, with specificity for decorated arabinogalactans [Bacteroides thetaiotaomicron VPI-5482]
4ZMH_A	1.71e-88	27	610	38	607	Crystalstructure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40],4ZMH_B Crystal structure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40]
7PUG_A	2.27e-86	6	614	20	626	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
4C90_A	1.96e-85	14	613	55	640	Evidencethat GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C90_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_A Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus]
7PXQ_A	3.47e-84	6	614	19	625	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000055	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003192_02648.