CAZyme Information: MGYG000003202_00533

Basic Information

• Species: UBA3263 sp900759865
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae; UBA3263; UBA3263 sp900759865
• CAZyme ID: MGYG000003202_00533
• CAZy Family: GT2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
421		47572.43	4.6536

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003202	2219551	MAG	United States	North America

• Gene Location: Start: 19187; End: 20452 Strand: -

Full Sequence      

MIRLNDFSSLELKRAAAQAEGEYTLLVLTGDRVESVDVRRMEQVARDTDALAVYGNYAKD
GVTVPLIEMQPGSVRDDFDFGPVMLVKTSQLTEFEQEVPELDFAAFYAFWLSVHERIAYV
PEVVSRVISVSADEESGEAQFRYVDPRNREAQLEKEDVFTRFLMRQEAFVEQGLRVSHDG
DFPIEASVIIPVRNRVRTVGDAIRSALSQITDFPFNVIVVDNHSDDGTTQLVARLAADSR
VVHIIPEPGHGIGGCWNVALDSELCGRFAIQLDSDDVYSSERTLQLIVDRFRDTGAACVI
GSYTLTDFDLHTIAPGLIDHAEWTDSNGANNALRINGLGAPRAYFTPIARKLRFPDVSYG
EDYAMVLRITREYKLARIFESLYFCRRWGGNSDSNLSQEKINANNRYKDWIRTVEFEARR
K

Enzyme Prediction     

No EC number prediction in MGYG000003202_00533.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	187	315	1.3e-18	0.7470588235294118

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd00761	Glyco_tranf_GTA_type	1.19e-19	188	305	1	117	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.
pfam00535	Glycos_transf_2	5.51e-15	187	302	1	114	Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.
COG0463	WcaA	1.54e-14	187	293	6	109	Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis].
cd06433	GT_2_WfgS_like	7.38e-12	187	395	1	202	WfgS and WfeV are involved in O-antigen biosynthesis. Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.
cd06423	CESA_like	1.24e-11	188	301	1	114	CESA_like is the cellulose synthase superfamily. The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QUB84322.1	6.98e-140	8	421	62	488
QCD34713.1	2.58e-134	1	419	1	428
QUB47643.1	7.36e-134	7	419	40	463
QCD38257.1	1.45e-132	7	421	5	439
ALO47901.1	9.37e-131	2	419	35	463

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
D4GUA0	3.94e-06	184	307	17	143	Glycosyltransferase AglD OS=Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) OX=309800 GN=aglD PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000071	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003202_00533.